The entire nucleotide sequence and classification of a hepatitis C virus isolate of a novel genotype from an Indonesian patient with chronic liver disease

Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

1989 • 6,910 citations

Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions.

1986 • 4,940 citations

Genetic organization and diversity of the hepatitis C virus.

1991 • 1,717 citations

Typing hepatitis C virus by polymerase chain reaction with type-specific primers: application to clinical surveys and tracing infectious sources

1992 • 1,288 citations

Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis.

1990 • 1,208 citations

Structure and organization of the hepatitis C virus genome isolated from human carriers

1991 • 970 citations

Molecular biology of the hepatitis C viruses: Implications for diagnosis, development and control of viral disease

1991 • 854 citations

Typing of hepatitis C virus isolates and characterization of new subtypes using a line probe assay

1993 • 703 citations

Detection of hepatitis C virus by polymerase chain reaction and response to interferon-α therapy: Relationship to genotypes of hepatitis C virus

1992 • 689 citations

Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis.

1991 • 636 citations

Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins

1991 • 611 citations

Nucleotide sequence and mutation rate of the H strain of hepatitis C virus.

1991 • 609 citations

Full-length sequence of a hepatitis C virus genome having poor homology to reported isolates: Comparative study of four distinct genotypes

1992 • 578 citations

Nucleotide sequence of the genomic RNA of hepatitis C virus isolated from a human carrier: comparison with reported isolates for conserved and divergent regions

1991 • 476 citations

Sequence variability in the 5' non-coding region of hepatitis C virus: identification of a new virus type and restrictions on sequence diversity

1993 • 437 citations

Analysis of a new hepatitis C virus type and its phylogenetic relationship to existing variants

1992 • 430 citations

Characterization of the terminal regions of hepatitis C viral RNA: identification of conserved sequences in the 5' untranslated region and poly(A) tails at the 3' end.

1991 • 426 citations

Sequence analysis of the 5' noncoding region of hepatitis C virus.

1992 • 410 citations

Characterization of the genomic sequence of type V (or 3a) hepatitis C virus isolates and PCR primers for specific detection

1993 • 396 citations

Genetic drift of hepatitis C virus during an 8.2-year infection in a chimpanzee: Variability and stability

1992 • 384 citations

Hypervariable regions in the putative glycoprotein of hepatitis C virus

1991 • 353 citations

There are two major types of hepatitis C virus in Japan

1990 • 335 citations

Detection of three types of hepatitis C virus in blood donors: investigation of type‐specific differences in serologic reactivity and rate of alanine aminotransferase abnormalities

1993 • 299 citations

The degree of variability in the amino terminal region of the E2/NS1 protein of hepatitis C virus correlates with responsiveness to interferon therapy in viremic patients

1992 • 295 citations

Genomic structure of the human prototype strain H of hepatitis C virus: comparison with American and Japanese isolates.

1991 • 281 citations

At least five related, but distinct, hepatitis C viral genotypes exist.

1992 • 267 citations

Genotypes and titers of hepatitis C virus for predicting response to interferon in patients with chronic hepatitis C

1994 • 234 citations

Clinical backgrounds of the patients having different types of hepatitis C virus genomes

1992 • 211 citations

The Taiwanese hepatitis C virus genome: Sequence determination and mapping the 5′ termini of viral genomic and antigenomic RNA

1992 • 189 citations

A new type of hepatitis C virus in patients in Thailand

1992 • 171 citations

Molecular cloning of hepatitis C virus genome from a single Japanese carrier: sequence variation within the same individual and among infected individuals

1992 • 148 citations

Characterization of hypervariable regions in the putative envelope protein of hepatitis C virus

1992 • 142 citations

Prevalence, genotypes, and an isolate (HC‐C2) of hepatitis C virus in Chinese patients with liver disease

1993 • 98 citations

Two French genotypes of hepatitis C virus: homology of the predominant genotype with the prototype American strain

1991 • 45 citations

Group specific sequences and conserved secondary structures at the 3′ end of HCV genome and its implication for viral replication

1992 • 37 citations

Sequence comparisons for a hepatitis C virus genome RNA isolated from a patient with liver cirrhosis

1992 • 31 citations