Identification of TRACs (T3 receptor-associating cofactors), a family of cofactors that associate with, and modulate the activity of, nuclear hormone receptors.

Experiments in molecular genetics

1972 • 28,260 citations

A novel genetic system to detect protein–protein interactions

1989 • 6,022 citations

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1993 • 5,680 citations

The RXR heterodimers and orphan receptors

1995 • 3,168 citations

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

1995 • 2,059 citations

Steroid hormone receptors: Many Actors in search of a plot

1995 • 1,854 citations

Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

1991 • 1,779 citations

The c-erb-A gene encodes a thyroid hormone receptor

1986 • 1,505 citations

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1991 • 1,371 citations

The c-erb-A protein is a high-affinity receptor for thyroid hormone

1986 • 1,340 citations

Transcription Factor Interactions: Selectors of Positive or Negative Regulation from a Single DNA Element

1990 • 1,326 citations

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

1992 • 944 citations

Steroid Receptor Family: Structure and Functions

1990 • 820 citations

Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor.

1995 • 756 citations

Estrogen Receptor-Associated Proteins: Possible Mediators of Hormone-Induced Transcription

1994 • 645 citations

Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist

1989 • 599 citations

Polarity-specific activities of retinoic acid receptors determined by a co-repressor

1995 • 569 citations

Isoform-specific amino-terminal domains dictate DNA-binding properties of ROR alpha, a novel family of orphan hormone nuclear receptors.

1994 • 485 citations

Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

1995 • 431 citations

Interaction of thyroid-hormone receptor with a conserved transcriptional mediator

1995 • 429 citations

Repression of transcription mediated at a thyroid hormone response element by the v-erb-A oncogene product

1989 • 387 citations

Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors.

1995 • 361 citations

From embryogenesis to metamorphosis: The regulation and function of drosophila nuclear receptor superfamily members

1995 • 347 citations

v-erbA oncogene activation entails the loss of hormone-dependent regulator activity of c-erbA

1990 • 236 citations

Nuclear thyroid hormone receptors.

1990 • 217 citations

Structure and expression of the gene responsible for the triplet repeat disorder, dentatorubral and pallidoluysian atrophy (DRPLA)

1994 • 202 citations

The viral erbA oncogene protein, a constitutive repressor in animal cells, is a hormone-regulated activator in yeast

1990 • 80 citations

Nuclear Hormone Receptors Involved in Neoplasia: Erb A Exhibits a Novel DNA Sequence Specificity Determined by Amino Acids Outside of the Zinc-Finger Domain

1993 • 57 citations

Identification of a domain required for oncogenic activity and transcriptional suppression by v-erbA and thyroid-hormone receptor alpha.

1993 • 54 citations

Role of the N terminus in DNA recognition by the v-erb A protein, an oncogenic derivative of a thyroid hormone receptor.

1995 • 17 citations