Receptor specific for certain nucleotides stimulates inositol phosphate metabolism and Ca²⁺ fluxes in A431 cells

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Lounging in a lysosome: the intracellular lifestyle of Coxiella burnetii

2007 • 11,720 citations

Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands

1982 • 2,148 citations

Extracellular ATP: effects, sources and fate

1986 • 1,666 citations

Early Signals in the Mitogenic Response

1986 • 1,498 citations

Activation of Calcium Entry by the Tumor Promoter Thapsigargin in Parotid Acinar Cells

1989 • 887 citations

Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model

1985 • 732 citations

Ion channels activated by inositol 1,4,5-trisphosphate in plasma membrane of human T-lymphocytes

1987 • 676 citations

Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells

1981 • 669 citations

Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones

1983 • 547 citations

Agonist-induced desensitization of the beta-adrenergic receptor-linked adenylate cyclase.

1983 • 441 citations

Enhancement of calcium uptake and phosphatidylinositol turnover by epidermal growth factor in A-431 cells

1981 • 426 citations

Epidermal growth factor stimulates tyrosine phosphorylation of phospholipase C-II independently of receptor internalization and extracellular calcium.

1989 • 402 citations

Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor.

1989 • 385 citations

Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism.

1985 • 332 citations

Purification of an 80,000-dalton protein that is a component of the isolated microvillus cytoskeleton, and its localization in nonmuscle cells.

1983 • 294 citations

Phorbol ester inhibits phosphoinositide hydrolysis and calcium mobilization in cultured astrocytoma cells.

1985 • 274 citations

Characterization of responses of isolated rat hepatocytes to ATP and ADP.

1985 • 269 citations

Phorbol ester and 1-oleoyl-2-acetylglycerol inhibit angiotensin activation of phospholipase C in cultured vascular smooth muscle cells.

1985 • 240 citations

The ATP4- receptor of rat mast cells

1980 • 227 citations

The calcium signal and phosphatidylinositol breakdown in 2H3 cells.

1984 • 214 citations

Involvement of inositol 1,4,5-trisphosphate and calcium in the action of adenine nucleotides on aortic endothelial cells.

1987 • 202 citations

Extracellular ATP4- promotes cation fluxes in the J774 mouse macrophage cell line.

1987 • 201 citations

Exogenous ATP raises cytoplasmic free calcium in fura‐2 loaded piglet aortic endothelial cells

1986 • 200 citations

Extracellular nucleotides mediate Ca2+ fluxes in J774 macrophages by two distinct mechanisms.

1988 • 189 citations

Characterization of inositol 1,4,5-trisphosphate receptors and calcium mobilization in a hepatic plasma membrane fraction.

1988 • 178 citations

The effects of bombesin on polyphosphoinositide and calcium metabolism in Swiss 3T3 cells.

1987 • 175 citations

The protein-tyrosine kinase substrate, p81, is homologous to a chicken microvillar core protein.

1986 • 173 citations

Increased free calcium in endothelial cells under stimulation with adenine nucleotides

1986 • 171 citations

Intracellular receptors for inositol 1,4,5-trisphosphate in angiotensin II target tissues.

1987 • 169 citations

Epidermal growth factor and angiotensin II stimulate formation of inositol 1,4,5- and inositol 1,3,4-trisphosphate in hepatocytes. Differential inhibition by pertussis toxin and phorbol 12-myristate 13-acetate.

1987 • 168 citations

Inositol(1,3,4,5)tetrakisphosphate-induced activation of sea urchin eggs requires the presence of inositol trisphosphate

1987 • 163 citations

Methods of Measuring Intracellular Calcium

1979 • 162 citations

Selectivity of cation chelation to tetracyclines: Evidence for special conformation of calcium chelate

1971 • 162 citations

Intracellular Ca2+ mobilization activated by extracellular ATP in Ehrlich ascites tumor cells.

1985 • 159 citations

Extracellular ATP is a mitogen for 3T3, 3T6, and A431 cells and acts synergistically with other growth factors.

1989 • 149 citations

Extracellular ATP perturbs transmembrane ion fluxes, elevates cytosolic [Ca2+], and inhibits phagocytosis in mouse macrophages.

1985 • 148 citations

Adenosine triphosphate stimulates inositol phospholipid metabolism and prostacyclin formation in adrenal medullary endothelial cells by means of P2-purinergic receptors.

1987 • 141 citations

Involvement of membrane calcium in the response of rabbit neutrophils to chemotactic factors as evidenced by the fluorescence of chlorotetracycline.

1979 • 128 citations

The migration of divalent cations in mitochondria visualized by a fluorescent chelate probe

1972 • 126 citations

Extracellular ATP activates polyphosphoinositide breakdown and Ca2+ mobilization in Ehrlich ascites tumor cells

1986 • 125 citations

Sensitivity of the response of cytosolic calcium in Quin-2-loaded rat hepatocytes to glucagon, adenine nucleosides, and adenine nucleotides.

1985 • 119 citations

Protein kinase C-mediated negative-feedback inhibition of unstimulated and bombesin-stimulated polyphosphoinositide hydrolysis in Swiss-mouse 3T3 cells

1987 • 114 citations

Specificity of P2-purinoceptor that mediates endothelium-dependent relaxation of the pig aorta

1985 • 112 citations

Intracellular divalent cation release in pancreatic acinar cells during stimulus-secretion coupling. I. Use of chlorotetracycline as fluorescent probe.

1978 • 108 citations

The effects of substance P and carbachol on inositol tris- and tetrakisphosphate formation and cytosolic free calcium in rat parotid acinar cells. A correlation between inositol phosphate levels and calcium entry.

1987 • 105 citations

Pertussis toxin or phorbol 12-myristate 13-acetate can distinguish between epidermal growth factor- and angiotensin-stimulated signals in hepatocytes.

1986 • 101 citations

Permeabilization of transformed cells in culture by external ATP

1985 • 92 citations

EGF raises cytosolic Ca2+ in A431 and Swiss 3T3 cells by a dual mechanism

1987 • 89 citations

Intracellular divalent cation release in pancreatic acinar cells during stimulus-secretion coupling. II. Subcellular localization of the fluorescent probe chlorotetracycline.

1978 • 83 citations

Studies on the increase in cytosolic free calcium induced by epidermal growth factor, serum, and nucleotides in individual A431 cells

1988 • 68 citations

Efflux of ⁴⁵CA²⁺ from human fibroblasts in response to serum or growth factors

1983 • 67 citations

Epidermal-growth-factor-induced formation of inositol phosphates in human A431 cells. Differences from the effect of bradykinin

1988 • 57 citations

Na+/H+ exchange in Ehrlich ascites tumor cells. Regulation by extracellular ATP and 12-O-tetradecanoylphorbol 13-acetate.

1986 • 53 citations

Extracellular ATP induces the release of calcium from intracellular stores without the activation of protein kinase C in Swiss 3T6 mouse fibroblasts.

1989 • 50 citations

Permeabilization of transformed mouse fibroblasts by 3′‐O‐(4‐benzoyl)benzoyl adenosine 5′‐triphosphate and the desensitization of the process

1989 • 46 citations

CALCIUM TRANSIENTS: MOBILIZATION OF INTRACELLULAR Ca2+

1986 • 46 citations

ATP‐induced calcium mobilization and inositol 1,4,5‐trisphosphate formation in H‐35 hepatoma cells

1986 • 45 citations

Phorbol esters and diacylglycerol inhibit vasopressin-induced increases in cytoplasmic-free Ca2+ and 45Ca2+ efflux in Swiss 3T3 cells

1986 • 39 citations

ATP-induced calcium mobilization in human neutrophils

1989 • 38 citations

GTP- and inositol 1,4,5-trisphosphate-induced release of 45Ca2+ from a membrane store co-localized with pancreatic-islet-cell plasma membrane

1988 • 37 citations

Concanavalin A induces the release of intracellular Ca2+ in intact rabbit thymocytes.

1980 • 32 citations

Exogenous ATP and other nucleoside phosphates modulate epidermal growth factor receptors of A-431 epidermoid carcinoma cells.

1989 • 30 citations

Effects of platelet-derived growth factor on Ca2+ in 3T3 cells

1985 • 27 citations

The rapid desensitization of receptors for platelet derived growth factor, bradykinin and ATP: Studies on individual cells using quantitative digital video fluorescence microscopy

1988 • 24 citations

On the role of protein phosphorylation in the ATP‐dependent permeabilization of transformed cells

1984 • 19 citations