S-Nitrosoglutathione Is Cleaved by the Thioredoxin System with Liberation of Glutathione and Redox Regulating Nitric Oxide

Tissue sulfhydryl groups

1959 • 25,130 citations

Superoxide Dismutase

1969 • 12,578 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Nitric oxide synthases: Roles, tolls, and controls

1994 • 2,945 citations

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

1993 • 2,423 citations

THIOREDOXIN

1985 • 1,885 citations

Thioredoxin and Glutaredoxin Systems

1989 • 1,778 citations

Redox signaling: Nitrosylation and related target interactions of nitric oxide

1994 • 1,732 citations

NO at work

1994 • 1,493 citations

S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds.

1992 • 1,454 citations

Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide.

1985 • 1,146 citations

[21] Thioredoxin and thioredoxin reductase

1995 • 932 citations

Soluble Guanylate Cyclase from Bovine Lung: Activation with Nitric Oxide and Carbon Monoxide and Spectral Characterization of the Ferrous and Ferric States

1994 • 641 citations

Endogenous nitrogen oxides and bronchodilator S-nitrosothiols in human airways.

1993 • 616 citations

NO+, NO , and NO− Donation by S-Nitrosothiols: Implications for Regulation of Physiological Functions by S-Nitrosylation and Acceleration of Disulfide Formation

1995 • 601 citations

Thioredoxin structure and mechanism: conformational changes on oxidation of the active-site sulfhydryls to a disulfide

1995 • 430 citations

Some observations concerning the S-nitroso and S-phenylsulphonyl derivatives of L-cysteine and glutathione

1985 • 389 citations

Reaction Kinetics for Nitrosation of Cysteine and Glutathione in Aerobic Nitric Oxide Solutions at Neutral pH. Insights into the Fate and Physiological Effects of Intermediates Generated in the NO/O2 Reaction

1994 • 384 citations

Nitric Oxide-stimulated Guanine Nucleotide Exchange on p21ras

1995 • 367 citations

S‐nitroso‐glutathione inhibits platelet activation in vitro and in vivo

1992 • 330 citations

Nitric oxide reacts with intracellular glutathione and activates the hexose monophosphate shunt in human neutrophils: evidence for S-nitrosoglutathione as a bioactive intermediary.

1994 • 316 citations

High-resolution solution structures of oxidized and reduced Escherichia coli thioredoxin

1994 • 261 citations

Kinetics of nitric oxide autoxidation in aqueous solution.

1994 • 225 citations

Selenodiglutathione is a highly efficient oxidant of reduced thioredoxin and a substrate for mammalian thioredoxin reductase.

1992 • 206 citations

Tryptophan Fluorescence Study of Conformational Transitions of the Oxidized and Reduced Form of Thioredoxin

1972 • 164 citations

Mutagenesis of structural half-cystine residues in human thioredoxin and effects on the regulation of activity by selenodiglutathione

1993 • 162 citations

Immunohistochemical localization of thioredoxin and thioredoxin reductase in adult rats.

1985 • 158 citations

Oxidation of critical cysteine residues of type I adenylyl cyclase by o-iodosobenzoate or nitric oxide reversibly inhibits stimulation by calcium and calmodulin.

1994 • 84 citations

Reduction of Phenoxyl Radicals by Thioredoxin Results in Selective Oxidation of Its SH-Groups to Disulfides. An Antioxidant Function of Thioredoxin

1995 • 46 citations

Novel synthesis of S-nitrosoglutathione and degradation by human neutrophils

1992 • 42 citations