Effects of chronic desipramine administration on the locus coeruleus neuronal activity in the learned helplessness paradigm

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1976 • 2,255 citations

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1967 • 1,860 citations

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1984 • 1,365 citations

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1967 • 1,162 citations

Catecholamine receptors on locus coeruleus neurons: Pharmacological characterization

1977 • 712 citations

Behavioral depression produced by an uncontrollable stressor: Relationship to norepinephrine, dopamine, and serotonin levels in various regions of rat brain

1981 • 659 citations

Evidence for norepinephrine-mediated collateral inhibition of locus coeruleus neurons

1977 • 490 citations

Activation of locus coeruleus neurons by peripheral stimuli: Modulation by a collateral inhibitory mechanism

1978 • 369 citations

Validation criteria for animal models of human mental disorders: Learned helplessness as a paradigm case

1986 • 333 citations

Learned helplessness: Theory and evidence.

1976 • 320 citations

Alterations in Brain Norepinephrine Metabolism Induced by Environmental Stimuli Previously Paired with Inescapable Shock

1980 • 263 citations

Catecholamine depletion in mice upon reexposure to stress: Mediation of the escape deficits produced by inescapable shock.

1979 • 238 citations

Deficits of escape performance following catecholamine depletion: Implications for behavioral deficits induced by uncontrollable stress

1979 • 196 citations

Long-term interference effect: An alternative to learned helplessness.

1976 • 178 citations

Animal Models in Human Psychobiology

1977 • 162 citations

A neuropharmacologically-relevant animal model of depression

1979 • 162 citations

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1983 • 160 citations

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1976 • 155 citations

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1979 • 153 citations

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1975 • 143 citations

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1981 • 120 citations

Altered activity of the locus coeruleus in an animal model of depression.

1988 • 117 citations

Desmethylimipramine (DMI) counteracts learned helplessness in rats

1979 • 98 citations

Chronic stress-induced changes in locus coeruleus neuronal activity

1990 • 95 citations

Escape deficits induced by uncontrollable stress: Antagonism by dopamine and norepinephrine agonists

1980 • 93 citations

Shuttle-box deficits induced by inescapable shocks in rats: Reversal by the beta-adrenoreceptor stimulants clenbuterol and salbutamol

1986 • 85 citations

Effects of long-term desipramine administration on noradrenergic neurotransmission: electrophysiological studies in the rat brain.

1991 • 76 citations

Effects of nortriptyline treatment on learned helplessness in the rat

1981 • 64 citations

Noradrenergic and opioid mediation of tricyclic-induced reversal of escape deficits caused by inescapable shock pretreatment in rats

1986 • 56 citations

Locus coeruleus norepinephrine-containing neurons: effects produced by acute and subchronic treatment with antipsychotic drugs and amphetamine

1986 • 55 citations

Antidepressants induce regeneration of catecholaminergic axon terminals in the rat cerebral cortex

1990 • 51 citations

Noradrenergic rather than GABAergic processes as the common mediation of the antidepressant profile of GABA agonists and imipramine-like drugs in animals

1987 • 43 citations

The reversal effect of antidepressants on the escape deficit induced by inescapable shock in rats

1983 • 36 citations

Uncontrollable shock, forebrain norepinephrine, and stimulus selection during choice-escape learning

1988 • 36 citations

Time course effects of uncontrollable stress in locus coeruleus neuronal activity

1991 • 32 citations

Delayed behavioral response to antidepressant drugs following selective damage to the hippocampal noradrenergic innervation in rats

1987 • 28 citations

Electrophysiological evidence for locus coeruleus norepinephrine autoreceptor subsensitivity following subchronic administration of d-amphetamine

1986 • 19 citations