The influence of intracellular calcium concentration on degranulation of dialysed mast cells from rat peritoneum.

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

2012 • 8,865 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate

1983 • 2,596 citations

Discrete changes of cell membrane capacitance observed under conditions of enhanced secretion in bovine adrenal chromaffin cells.

1982 • 1,010 citations

Role of guanine nucleotide binding protein in the activation of polyphosphoinositide phosphodiesterase

1985 • 960 citations

Calcium messenger system: an integrated view.

1984 • 916 citations

Repetitive transient rises in cytoplasmic free calcium in hormone-stimulated hepatocytes

1986 • 790 citations

myo-Inositol 1,4,5-trisphosphate. A second messenger for the hormonal mobilization of intracellular Ca2+ in liver.

1984 • 567 citations

Simultaneous inhibitions of inositol phospholipid breakdown, arachidonic acid release, and histamine secretion in mast cells by islet-activating protein, pertussis toxin. A possible involvement of the toxin-specific substrate in the Ca2+-mobilizing receptor-mediated biosignaling system.

1985 • 509 citations

Capacitance measurements reveal stepwise fusion events in degranulating mast cells

1984 • 506 citations

Involvement of guanine nucleotide-binding protein in the gating of Ca2+ by receptors

1983 • 473 citations

Activation of Mast Cells for Mediator Release through IgE Receptors

2015 • 369 citations

The Ca signal from fura‐2 loaded mast cells depends strongly on the method of dye‐loading

1985 • 356 citations

The mechanism of the calcium signal and correlation with histamine release in 2H3 cells.

1984 • 351 citations

Two roles for guanine nucleotides in the stimulus-secretion sequence of neutrophils

1986 • 339 citations

Protein kinase C activation of physiological processes in human neutrophils at vanishingly small cytosolic Ca2+ levels

1984 • 334 citations

Receptor-Coupled Activation of Phosphoinositide-Specific Phospholipase C by an N Protein

1986 • 324 citations

Oscillations of intracellular Ca2+ in mammalian cardiac muscle

1983 • 266 citations

The relationship between histamine secretion and ⁴⁵calcium‐uptake by mast cells

1977 • 265 citations

Stimulation of phospholipid methylation, Ca2+ influx, and histamine release by bridging of IgE receptors on rat mast cells.

1980 • 256 citations

Calcium-Induced Extrusion of Secretory Granules (Exocytosis) in Mast Cells Exposed to 48/80 or the Ionophores A-23187 and X-537A

1974 • 253 citations

Guanine nucleotides decrease the free [Ca²⁺] required for secretion of serotonin from permeabilized blood platelets

1984 • 236 citations

Phorbol 12-myristate 13-acetate activates rabbit neutrophils without an apparent rise in the level of intracellular free calcium

1983 • 217 citations

The calcium signal and phosphatidylinositol breakdown in 2H3 cells.

1984 • 214 citations

EGTA purity and the buffering of calcium ions in physiological solutions

1984 • 208 citations

Thyrotropin-releasing hormone activates a Ca2+-dependent polyphosphoinositide phosphodiesterase in permeable GH3 cells. GTP gamma S potentiation by a cholera and pertussis toxin-insensitive mechanism.

1986 • 197 citations

Intracellularly injected tetanus toxin inhibits exocytosis in bovine adrenal chromaffin cells

1986 • 183 citations

IgE-mediated degranulation of mast cells does not require opening of ion channels

1986 • 179 citations

Activation of Phospholipid Metabolism During Mediator Release from Stimulated Rat Mast Cells

1979 • 165 citations

A patch-clamp study of histamine-secreting cells.

1986 • 147 citations

Exocytosis (Secretory Granule Extrusion) Induced by Injection of Calcium into Mast Cells

1973 • 128 citations

Rat mast cells permeabilised with streptolysin O secrete histamine in response to Ca2+ at concentrations buffered in the micromolar range

1987 • 126 citations

Rat mast cells permeabilized with ATP secrete histamine in response to calcium ions buffered in the micromolar range.

1981 • 119 citations

Direct demonstration of increased intracellular concentration of free calcium as measured by quin-2 in stimulated rat peritoneal mast cell.

1984 • 118 citations

The removal of myoplasmic free calcium following calcium release in frog skeletal muscle.

1986 • 115 citations

Fast calcium transients in rat peritoneal mast cells are not sufficient to trigger exocytosis.

1986 • 104 citations

The effect of inositol trisphosphate on Ca2+ fluxes in insulin-secreting tumor cells.

1984 • 104 citations

Regulation of cytosolic free Ca2+ concentration in acinar cells of rat pancreas

1983 • 81 citations

Intracellular calcium ions and calcium currents in perfused neurones of the snail, Lymnaea stagnalis.

1984 • 79 citations

Quantitative analysis of mast cell structure

1974 • 70 citations

Calcium buffering in axons and axoplasm of Loligo.

1987 • 45 citations

Loss of quin 2 accompanies degranulation of mast cells

1986 • 15 citations