Smad3 Deficiency Ameliorates Experimental Obliterative Bronchiolitis in a Heterotopic Tracheal Transplantation Model

Role of Transforming Growth Factor β in Human Disease

2000 • 2,405 citations

NEW EMBO MEMBERS REVIEW: Transcriptional control by the TGF-beta/Smad signaling system

2000 • 1,935 citations

Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

1999 • 890 citations

TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway

1999 • 667 citations

Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex.

1990 • 647 citations

Identification of Novel TGF-β/Smad Gene Targets in Dermal Fibroblasts using a Combined cDNA Microarray/Promoter Transactivation Approach

2001 • 628 citations

Inhibition of Transforming Growth Factor (TGF)-β1–Induced Extracellular Matrix with a Novel Inhibitor of the TGF-β Type I Receptor Kinase Activity: SB-431542

2002 • 609 citations

The Connective Tissue Growth Factor/Cysteine- Rich 61/Nephroblastoma Overexpressed (CCN) Family*

1999 • 567 citations

Targeted Disruption of Smad3 Reveals an Essential Role in Transforming Growth Factor β-Mediated Signal Transduction

1999 • 475 citations

CTGF and SMADs, Maintenance of Scleroderma Phenotype Is Independent of SMAD Signaling

2001 • 419 citations

Transient gene transfer and expression of Smad7 prevents bleomycin-induced lung fibrosis in mice

1999 • 400 citations

Functional Characterization of Transforming Growth Factor β Signaling in Smad2- and Smad3-deficient Fibroblasts

2001 • 397 citations

The Registry of the International Society for Heart and Lung Transplantation: twenty-first official adult lung and heart-lung transplant report—2004

2004 • 396 citations

Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice

2002 • 391 citations

Stimulation of Type I Collagen Transcription in Human Skin Fibroblasts by TGF-β: Involvement of Smad 3

1999 • 388 citations

Bronchiolitis Obliterans after Human Lung Transplantation

2002 • 383 citations

The Connective Tissue Growth Factor/Cysteine- Rich 61/Nephroblastoma Overexpressed (CCN) Family

1999 • 368 citations

Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy?

2002 • 337 citations

Collagen deposition in HIV-1 infected lymphatic tissues and T cell homeostasis

2002 • 262 citations

Transforming Growth Factor-β Repression of Matrix Metalloproteinase-1 in Dermal Fibroblasts Involves Smad3

2001 • 247 citations

Connective tissue growth factor mRNA expression is upregulated in bleomycin-induced lung fibrosis

1998 • 242 citations

Reproduction of the obliterative bronchiolitis lesion after heterotopic transplantation of mouse airways.

1993 • 232 citations

Prevalence and outcome of bronchiolitis obliterans syndrome after lung transplantation

1995 • 194 citations

Transforming growth factor beta (TGF-β) and obliterative bronchiolitis following pulmonary transplantation

1999 • 175 citations

Smad pathway is activated in the diabetic mouse kidney and Smad3 mediates TGF-β-induced fibronectin in mesangial cells

2002 • 167 citations

Transforming growth factor-beta and matrix protein expression in acute and chronic rejection of human renal allografts.

1995 • 148 citations

LYMPHOCYTIC AIRWAY INFILTRATION AS A PRECURSOR TO FIBROUS OBLITERATION IN A RAT MODEL OF BRONCHIOLITIS OBLITERANS1,2

1997 • 119 citations

Collagen deposition in HIV-1 infected lymphatic tissues and T cell homeostasis

2002 • 102 citations

Autoinduction of Transforming Growth Factor β1 Is Mediated by the AP-1 Complex

1990 • 99 citations

Oral Tolerance Induction by Type V Collagen Downregulates Lung Allograft Rejection

2001 • 98 citations

Induction of Platelet-derived Growth Factor B-chain Expression by Transforming Growth Factor-β Involves Transactivation by Smads

2000 • 94 citations

Gene Transfer for Transplantation Prolongation of Allograft Survival with Transforming Growth Factor-β1

1994 • 66 citations

Transforming growth factor β in relation to cardiac allograft vasculopathy after heart transplantation

2000 • 63 citations

PEAKS OF TRANSFORMING GROWTH FACTOR-?? mRNA IN ALVEOLAR CELLS OF LUNG TRANSPLANT RECIPIENTS AS AN EARLY MARKER OF CHRONIC REJECTION

1998 • 58 citations

Role of Platelet-derived Growth Factor in Obliterative Bronchiolitis (Chronic Rejection) in the Rat

1999 • 52 citations

Soluble Transforming Growth Factor- β Type III Receptor Gene Transfection Inhibits Fibrous Airway Obliteration in a Rat Model of Bronchiolitis Obliterans

2002 • 52 citations

FIBROSIS IN CHRONIC REJECTION OF HUMAN LIVER ALLOGRAFTS

1996 • 48 citations

Extracellular matrix analogs as carriers for growth factors: In vitro fibroblast behavior

1993 • 44 citations

Transforming growth factor–β1 gene transfer ameliorates acute lung allograft rejection

2000 • 19 citations

Differential effects of soluble and immobilized fibronectins on aortic endothelial cell proliferation and attachment

1987 • 7 citations