Mechanical compression drives cancer cells toward invasive phenotype

Cell Migration: Integrating Signals from Front to Back

2003 • 4,755 citations

Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis

2004 • 3,727 citations

Tensional homeostasis and the malignant phenotype

2005 • 3,655 citations

Collective cell migration in morphogenesis, regeneration and cancer

2009 • 2,503 citations

A tense situation: forcing tumour progression

2009 • 1,787 citations

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

2009 • 1,616 citations

Patterning proteins and cells using soft lithography

1999 • 1,463 citations

Reversion of the Malignant Phenotype of Human Breast Cells in Three-Dimensional Culture and In Vivo by Integrin Blocking Antibodies

1997 • 1,444 citations

Focal Contacts as Mechanosensors

2001 • 1,390 citations

TGFβ: the molecular Jekyll and Hyde of cancer

2006 • 1,228 citations

Biomechanics and biophysics of cancer cells☆

2007 • 1,187 citations

Mechanism of Blebbistatin Inhibition of Myosin II

2004 • 973 citations

Adhesion-Dependent Cell Mechanosensitivity

2003 • 847 citations

Emergent patterns of growth controlled by multicellular form and mechanics

2005 • 822 citations

Solid stress inhibits the growth of multicellular tumor spheroids

1997 • 801 citations

Cancer cells compress intratumour vessels

2004 • 781 citations

Cartilage Tissue Remodeling in Response to Mechanical Forces

2000 • 630 citations

Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage

2009 • 612 citations

Tissue Geometry Determines Sites of Mammary Branching Morphogenesis in Organotypic Cultures

2006 • 592 citations

Mechanotransduction in Response to Shear Stress

1999 • 560 citations

Cell shape provides global control of focal adhesion assembly

2003 • 535 citations

Microcontact printing: A tool to pattern

2006 • 506 citations

Microvascular pressure is the principal driving force for interstitial hypertension in solid tumors: implications for vascular collapse.

1992 • 501 citations

Mechanical Induction of Twist in the Drosophila Foregut/Stomodeal Primordium

2003 • 498 citations

Fluid forces control endothelial sprouting

2011 • 458 citations

Effects of biomechanical stress on bones in animals

2002 • 437 citations

Tumor Microvasculature and Microenvironment: Novel Insights Through Intravital Imaging in Pre-Clinical Models

2010 • 432 citations

Micro-Environmental Mechanical Stress Controls Tumor Spheroid Size and Morphology by Suppressing Proliferation and Inducing Apoptosis in Cancer Cells

2009 • 427 citations

Tensegrity-based mechanosensing from macro to micro

2008 • 418 citations

Beyond polymer polarity: how the cytoskeleton builds a polarized cell

2008 • 363 citations

Interstitial fluid flow induces myofibroblast differentiation and collagen alignment in vitro

2005 • 349 citations

Mechanisms of collective cell migration at a glance

2009 • 348 citations

Seed and Soil

1905 • 305 citations

The “seed and soil” hypothesis revisited

2008 • 277 citations

Rho-dependent formation of epithelial “leader” cells during wound healing

2003 • 217 citations

Human breast carcinoma desmoplasia is PDGF initiated

2000 • 214 citations

Glycocalyx modulates the motility and proliferative response of vascular endothelium to fluid shear stress

2007 • 199 citations

Modeling Interstitial Flow in an Artery Wall Allows Estimation of Wall Shear Stress on Smooth Muscle Cells

1995 • 194 citations

Fibroblast alignment under interstitial fluid flow using a novel 3-D tissue culture model

2003 • 171 citations

Epithelial–mesenchymal transition (EMT) is not sufficient for spontaneous murine breast cancer metastasis

2008 • 128 citations

Mitochondrial bioenergetic adaptations of breast cancer cells to aglycemia and hypoxia

2010 • 108 citations

Lowering of Tumor Interstitial Fluid Pressure Reduces Tumor Cell Proliferation in a Xenograft Tumor Model

2006 • 102 citations

Solid stress facilitates spheroid formation: potential involvement of hyaluronan

2002 • 79 citations

Shear Stress Modulation of Smooth Muscle Cell Marker Genes in 2-D and 3-D Depends on Mechanotransduction by Heparan Sulfate Proteoglycans and ERK1/2

2010 • 71 citations

Morphogenetic adaptation of the looping embryonic heart to altered mechanical loads

2006 • 49 citations

Transforming Growth Factor β Controls the Directional Migration of Hepatocyte Cohorts by Modulating Their Adhesion to Fibronectin

2007 • 31 citations

Stretch and Shear Interactions Affect Intercellular Junction Protein Expression and Turnover in Endothelial Cells

2009 • 29 citations

Epithelial membrane polarity: a stable, differentiated feature of an established human breast carcinoma cell line MCF-7.

1987 • 25 citations

Tumor–lymphatic interactions in an activated stromal microenvironment

2006 • 14 citations