Growth of 293 Cells in Suspension Culture

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

Cellular tumorigenicity in nude mice: Correlation with cell growth in semi-solid medium

1974 • 814 citations

Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage independent growth in vitro.

1975 • 747 citations

Transcriptional activation of cloned human β-globin genes by viral immediate-early gene products

1983 • 373 citations

Host-range mutants of adenovirus type 5 defective for growth in HeLa cells

1977 • 330 citations

cis and trans activation of globin gene transcription in transient assays.

1983 • 257 citations

Activation of gene expression by adenovirus and herpesvirus regulatory genes acting in trans and by a cis-acting adenovirus enhancer element

1983 • 250 citations

Infection of eucaryotic cells by helper-independent recombinant adenoviruses: early region 1 is not obligatory for integration of viral DNA

1984 • 170 citations

Adenovirus early region 1A protein activates transcription of a nonviral gene introduced into mammalian cells by infection or transfection.

1984 • 167 citations

PROPAGATION AND IN VITRO STUDIES OF PREVIOUSLY NON-CULTIVABLE ENTERAL ADENOVIRUSES IN 293 CELLS

1981 • 143 citations

Simian virus 40 replication in adenovirus-transformed human cells antagonizes gene expression

1985 • 143 citations

Development of a helper-independent human adenovirus vector and its use in the transfer of the herpes simplex virus thymidine kinase gene

1986 • 113 citations

Diagnosis of fastidious enteric adenoviruses 40 and 41 in stool specimens

1984 • 80 citations

Intracellular localization of adenovirus type 5 tumor antigens in productively infected cells

1983 • 79 citations

Repression of simian virus 40 early transcription by viral DNA replication in human 293 cells

1985 • 65 citations

Expression of dihydrololate reductase, and of the adjacent Elb region, in an Ad5-dihydrofolate reductase recombinant virus

1984 • 53 citations

The Genetic System

1984 • 29 citations

The Kinetics of Synthesis of Early Viral Proteins in KB Cells Infected with Wild-type and Transformation-defective Host-range Mutants of Human Adenovirus Type 5

1984 • 26 citations