Binding of Antipsychotic Drugs to Cortical 5-HT_2A Receptors: A PET Study of Chlorpromazine, Clozapine, and Amisulpride in Schizophrenic Patients

Clozapine for the Treatment-Resistant Schizophrenic

1988 • 4,030 citations

Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics

1990 • 2,630 citations

Positron Emission Tomographic Analysis of Central D1 and D2 Dopamine Receptor Occupancy in Patients Treated With Classical Neuroleptics and Clozapine

1992 • 1,420 citations

Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values.

1989 • 1,313 citations

A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography

1984 • 959 citations

D1, D2, and 5-HT2 receptor occupancy in relation to clozapine serum concentration: a PET study of schizophrenic patients

1995 • 341 citations

The Risks and Benefits of Clozapine versus Chlorpromazine

1987 • 299 citations

Treatment of Negative Symptoms in Schizophrenia with Amisulpride

1995 • 219 citations

Loss of brain 5-HT₂receptors in Alzheimer's disease

1993 • 171 citations

Improvement of some schizophrenic deficit symptoms with low doses of amisulpride

1995 • 145 citations

Serotonin-2 binding sites in human frontal cortex and hippocampus. Selective loss of S-2A sites with age

1984 • 139 citations

A Method for the In Vivo Investigation of the Serotonergic 5‐HT₂ Receptors in the Human Cerebral Cortex Using Positron Emission Tomography and ¹⁸F‐Labeled Setoperone

1990 • 110 citations

Autoradiographic analysis of age-dependent changes in serotonin 5-HT2 receptors of the human brain postmortem

1990 • 92 citations

Effect of typical and atypical antipsychotic drugs on 5-HT2 receptor density in rat cerebral cortex

1989 • 91 citations

In vivo characteristics of dopamine D2 receptor occupancy by amisulpride in schizophrenia

1996 • 82 citations

Differential Effect of Subchronic Treatment with Various Neuroleptic Agents on Serotonin₂ Receptors in Rat Cerebral Cortex

1986 • 80 citations

Drug‐receptor dissociation time, new tool for drug research: Receptor binding affinity and drug‐receptor dissociation profiles of serotonin‐S₂, Dopamine‐D₂, histamine‐H₁ antagonists, and opiates

1986 • 79 citations

Comparison of the In-vitro Receptor Selectivity of Substituted Benzamide Drugs for Brain Neurotransmitter Receptors

1988 • 58 citations

Blood–Cerebrospinal Fluid and Blood‐Brain Barriers Imaged by ¹⁸F‐Labeled Metabolites of ¹⁸F‐Setoperone Studied in Humans Using Positron Emission Tomography

1992 • 19 citations