RAGE is the Major Receptor for the Proinflammatory Activity of HMGB1 in Rodent Macrophages
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Abstract
References (35)
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
2002 • 4,011 citations
HMG-1 as a Late Mediator of Endotoxin Lethality in Mice
1999 • 3,314 citations
Involvement of Toll-like Receptors 2 and 4 in Cellular Activation by High Mobility Group Box 1 Protein
2004 • 1,533 citations
High Mobility Group 1 Protein (Hmg-1) Stimulates Proinflammatory Cytokine Synthesis in Human Monocytes
2000 • 1,385 citations
Blockade of RAGE–amphoterin signalling suppresses tumour growth and metastases
2000 • 1,200 citations
The Receptor for Advanced Glycation End Products (RAGE) Is a Cellular Binding Site for Amphoterin
1995 • 1,116 citations
The nuclear protein HMGB1 is secreted by monocytes via a non‐classical, vesicle‐mediated secretory pathway
2002 • 890 citations
Regulation of DNA-Dependent Activities by the Functional Motifs of the High-Mobility-Group Chromosomal Proteins
1999 • 837 citations
High-Mobility-Group Chromosomal Proteins: Architectural Components That Facilitate Chromatin Function
1996 • 752 citations
Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells
2003 • 721 citations
Cutting Edge: HMG-1 as a Mediator of Acute Lung Inflammation
2000 • 687 citations
Receptor for Advanced Glycation End Products (RAGE)-mediated Neurite Outgrowth and Activation of NF-κB Require the Cytoplasmic Domain of the Receptor but Different Downstream Signaling Pathways
1999 • 621 citations
HMGB1 as a Late Mediator of Lethal Systemic Inflammation
2001 • 481 citations
Structural features of the HMG chromosomal proteins and their genes
1990 • 474 citations
The High Mobility Group (Hmg) Boxes of the Nuclear Protein Hmg1 Induce Chemotaxis and Cytoskeleton Reorganization in Rat Smooth Muscle Cells
2001 • 454 citations
NEW EMBO MEMBERS' REVIEW: The double life of HMGB1 chromatin protein: architectural factor and extracellular signal
2001 • 429 citations
Revised nomenclature for high mobility group (HMG) chromosomal proteins
2001 • 369 citations
Structural Basis for the Proinflammatory Cytokine Activity of High Mobility Group Box 1
2003 • 343 citations
High mobility group 1 B‐box mediates activation of human endothelium
2003 • 321 citations
Proinflammatory cytokines (tumor necrosis factor and interleukin 1) stimulate release of high mobility group protein-1 by pituicytes
1999 • 294 citations
High mobility group box chromosomal protein 1: A novel proinflammatory mediator in synovitis
2002 • 287 citations
Inducible nitric oxide synthase is critical for immune-mediated liver injury in mice
2001 • 194 citations
Upwardly mobile proteins
2000 • 152 citations
HMG-1 REDISCOVERED AS A CYTOKINE
2001 • 148 citations
Tissue specificity of nucleo‐cytoplasmic distribution of HMG1 and HMG2 proteins and their probable functions
1989 • 128 citations
Dual roles for HMGB1: DNA binding and cytokine
2001 • 121 citations
Hmg4,a New Member of theHmg1/2Gene Family
1998 • 93 citations
Interactions between an HMG-1 protein and members of the Rel family
1999 • 77 citations
High Mobility Group Box Chromosomal Protein 1 (HMGB1) Is an Antibacterial Factor Produced by the Human Adenoid
2002 • 64 citations
Targeting high mobility group box 1 as a late-acting mediator of inflammation
2003 • 56 citations
The Modulation of Hepatic Injury and Heat Shock Expression by Inhibition of Inducible Nitric Oxide Synthase After Hemorrhagic Shock
2002 • 47 citations
Proinflammatory cytokines (tumor necrosis factor and interleukin 1) stimulate release of high mobility group protein-1 by pituicytes
1999 • 30 citations
High Mobility Group Box Chromosomal Protein 1 (HMGB1) Is an Antibacterial Factor Produced by the Human Adenoid
2002 • 11 citations
Coagulation and inflammation
2001 • 2 citations
Deleted Work
1955 • 0 citations