Successful selection for increased longevity in Drosophila: Analysis of the survival data and presentation of a hypothesis on the genetic regulation of longevity

Biostatistical Analysis.

1975 • 10,200 citations

Genetic variations of Drosophila melanogaster

1967 • 2,612 citations

LABORATORY EVOLUTION OF POSTPONED SENESCENCE INDROSOPHILA MELANOGASTER

1984 • 774 citations

Laboratory Evolution of Postponed Senescence in Drosophila melanogaster

1984 • 641 citations

SELECTION FOR DELAYED SENESCENCE IN DROSOPHILA MELANOGASTER

1984 • 562 citations

GENETICS OF LIFE HISTORY IN DROSOPHILA MELANOGASTER. II. EXPLORATORY SELECTION EXPERIMENTS

1981 • 414 citations

The uniqueness of the individual

1957 • 315 citations

The genetic control of wing development inDrosophila

1940 • 279 citations

The uniqueness of the individual

1957 • 248 citations

Selection for life span in Drosophila melanogaster

1985 • 247 citations

Selection for Delayed Senescence in Drosophila melanogaster

1984 • 239 citations

A GENETIC ANALYSIS OF TARGETED GROWTH IN MICE

1984 • 170 citations

The effects of gene-environment interaction on the expression of longevity

1985 • 148 citations

Testing the Theories of Aging

1983 • 132 citations

Genetic regulation of tissue-specific expression of amylase structural genes in Drosophila melanogaster.

1978 • 123 citations

The roles of juvenile hormone and 20-hydroxy-ecdysone during vitellogenesis in isolated abdomens of Drosophila melanogaster

1979 • 114 citations

The Effects of Larval Crowding and Body Size on the Longevity of Adult Drosophila Melanogaster

1958 • 113 citations

Quantitative variation and gene number

1975 • 101 citations

Influence of preimaginal environment on fecundity and ageing in Drosophila melanogaster hybrids—III. Developmental speed and life-span

1971 • 82 citations

Evolution of longevity in primates

1976 • 80 citations

Molecular Biology of Aging

1985 • 73 citations

Experimental Studies on the Duration of Life. VIII. The Influence Upon Duration of Life of Certain Mutant Genes of Drosophila melanogaster

1923 • 73 citations

The Lansing effect revisited—I. Life-span

1974 • 72 citations

Genetic determination of the α-galactosidase developmental program in mice

1975 • 63 citations

Evolutionary Theory in Gerontology

1982 • 60 citations

An Attempt to Select for Increased Longevity in <i>Drosophila melanogaster</i>

1979 • 59 citations

Genetic regulation of the catalase developmental program in maize scutellum: Identification of a temporal regulatory gene

1980 • 58 citations

Experimental Studies on the Duration of Life. II. Hereditary Differences in Duration of Life in Line-Bred Strains of Drosophila

1922 • 44 citations

THE LANSING EFFECT REVISITED. II.-CUMULATIVE AND SPONTANEOUSLY REVERSIBLE PARENTAL AGE EFFECTS ON FECUNDITY INDROSOPHILA MELANOGASTER

1977 • 41 citations

Specific disappearance of translatable messenger RNA for elongation factor one in aging Drosophila melanogaster

1984 • 35 citations

A mutation in Drosophila that appears to accelerate aging

1983 • 32 citations

On Statistical Tests of Significance in Studies of Survivorship in Laboratory Animals

1984 • 29 citations

The effect of some genotypes on the longevity of adult Drosophila

1978 • 27 citations

GENETIC DETERMINATION OF THE DEVELOPMENTAL PROGRAM FOR MOUSE LIVER β-GALACTOSIDASE: INVOLVEMENT OF SITES PROXIMATE TO AND DISTANT FROM THE STRUCTURAL GENE

1979 • 26 citations

Genetic determination of the developmental program for maize scutellar alcohol dehydrogenase: Involvement of a recessive, trans-acting, temporal-regulatory gene

1979 • 25 citations

The Lansing Effect Revisited. II.-Cumulative and Spontaneously Reversible Parental Age Effects on Fecundity in Drosophila melanogaster

1977 • 24 citations

Growth rate and life span in Drosophila. III. Effect of body size and development temperature on the biphasic relationship between growth rate and life span

1984 • 24 citations

Molecular Genetics of Aging

1978 • 21 citations

Linkage of conidial longevity determinant genes in Neurospora crassa

1984 • 18 citations

Experimental Studies on the Duration of Life. V. On the Influence of Certain Environmental Factors on Duration of Life in Drosophila

1922 • 16 citations

Developmental time and adult longevity in two strains of Drosophila melanogaster in a constant low-stress environment

1984 • 14 citations

Genetics of Aging: Effective Selection for Increased Longevity in Drosophila

1986 • 13 citations

Genetic control of adult lifespan in Drosophila melanogaster

1985 • 12 citations

Genetics

1981 • 11 citations