The three size classes of mouse NCAM proteins arise from a single gene by a combination of alternative splicing and use of different polyadenylation sites
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References (30)
Neural Cell Adhesion Molecule: Structure, Immunoglobulin-Like Domains, Cell Surface Modulation, and Alternative RNA Splicing
1987 • 1,134 citations
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1983 • 1,017 citations
Kinetics of homophilic binding by embryonic and adult forms of the neural cell adhesion molecule.
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1986 • 630 citations
The 180-kD component of the neural cell adhesion molecule N-CAM is involved in cell-cell contacts and cytoskeleton-membrane interactions
1987 • 303 citations
Differentiation state-dependent surface mobilities of two forms of the neural cell adhesion molecule
1986 • 262 citations
Phosphatidylinositol is involved in the membrane attachment of NCAM-120, the smallest component of the neural cell adhesion molecule.
1986 • 232 citations
Isolation and nucleotide sequence of mouse NCAM cDNA that codes for a Mr 79,000 polypeptide without a membrane-spanning region.
1987 • 231 citations
Human muscle neural cell adhesion molecule (N-CAM): Identification of a muscle-specific sequence in the extracellular domain
1987 • 221 citations
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1983 • 217 citations
Selective expression of the 180-kD component of the neural cell adhesion molecule N-CAM during development.
1985 • 196 citations
Molecular forms of N-CAM and its RNA in developing and denervated skeletal muscle.
1986 • 190 citations
cDNA clones of the neural cell adhesion molecule (N-CAM) lacking a membrane-spanning region consistent with evidence for membrane attachment via a phosphatidylinositol intermediate.
1986 • 158 citations
Biosynthesis, membrane association, and release of N-CAM-120, a phosphatidylinositol-linked form of the neural cell adhesion molecule.
1987 • 154 citations
Differential splicing and alternative polyadenylation generates distinct NCAM transcripts and proteins in the mouse.
1988 • 146 citations
Complete nucleotide sequence of the fast skeletal troponin T gene
1986 • 146 citations
Localization of the human NCAM gene to band q23 of chromosome 11: the third gene coding for a cell interaction molecule mapped to the distal portion of the long arm of chromosome 11.
1986 • 131 citations
Changes in neural cell adhesion molecule (NCAM) structure during vertebrate neural development.
1987 • 129 citations
Skeletal muscle neural cell adhesion molecule (N-CAM): changes in protein and mRNA species during myogenesis of muscle cell lines.
1987 • 124 citations
Alternatively spliced mRNAs code for different polypeptide chains of the chicken neural cell adhesion molecule (N-CAM).
1986 • 122 citations
Identification of a cDNA clone that contains the complete coding sequence for a 140-kD rat NCAM polypeptide.
1987 • 110 citations
Differential expression of mouse neural cell-adhesion molecule (N-CAM) mRNA species during brain development and in neural cell lines
1986 • 102 citations
NCAM: the molecule and its genetics
1986 • 92 citations
Topography of N-CAM structural and functional determinants. II. Placement of monoclonal antibody epitopes.
1986 • 90 citations
Nerve growth factor-induced changes in neural cell adhesion molecule (N-CAM) in PC12 cells.
1987 • 89 citations
Topographic localization of the heparin-binding domain of the neural cell adhesion molecule N-CAM.
1986 • 72 citations
Release of the 120 kDa component of the mouse neural cell adhesion molecule N-CAM from cell surfaces by phosphatidylinositol-specific phospholipase C
1986 • 70 citations
Analysis of cDNA clones that code for the transmembrane forms of the mouse neural cell adhesion molecule (NCAM) and are generated by alternative RNA splicing
1987 • 56 citations
Individual neural cell types express immunologically distinct N-CAM forms.
1985 • 49 citations
cDNA clones of the neural cell adhesion molecule (N-CAM) lacking a membrane-spanning region consistent with evidence for membrane attachment via a phosphatidylinositol intermediate
1987 • 21 citations