Aggregation of the high-affinity IgE receptor and enhanced activity of p53/56lyn protein-tyrosine kinase.

Complete structure and expression in transfected cells of high affinity IgE receptor

1989 • 515 citations

Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases

1992 • 503 citations

Dimeric immunoglobulin E serves as a unit signal for mast cell degranulation.

1977 • 366 citations

Phosphorylation and dephosphorylation of the high-affinity receptor for immunoglobulin E immediately after receptor engagement and disengagement

1991 • 272 citations

Tyrosine phosphorylation coupled to IgE receptor-mediated signal transduction and histamine release.

1990 • 234 citations

Protein-tyrosine kinase p72syk in high affinity IgE receptor signaling. Identification as a component of pp72 and association with the receptor gamma chain after receptor aggregation.

1993 • 232 citations

Fc epsilon RI-mediated tyrosine phosphorylation and activation of the 72-kDa protein-tyrosine kinase, PTK72, in RBL-2H3 rat tumor mast cells.

1992 • 231 citations

Multichain immune recognition receptors: similarities in structure and signaling pathways

1992 • 210 citations

Transphosphorylation as the mechanism by which the high-affinity receptor for IgE is phosphorylated upon aggregation.

1994 • 194 citations

Larger oligomers of IgE are more effective than dimers in stimulating rat basophilic leukemia cells.

1980 • 151 citations

Protein-tyrosine phosphorylation: an essential component of FcεRI signaling

1992 • 141 citations

Analysis of Ig-alpha-tyrosine kinase interaction reveals two levels of binding specificity and tyrosine phosphorylated Ig-alpha stimulation of Fyn activity.

1994 • 135 citations

Distinct p53/56lyn and p59fyn domains associate with nonphosphorylated and phosphorylated Ig-alpha.

1994 • 127 citations

Further characterization of the β-component of the receptor for immunoglobulin E

1982 • 106 citations

Qualitative characteristics of histamine release from human basophils by covalently cross-linked IgE.

1981 • 51 citations

Dynamics of signal transduction after aggregation of cell-surface receptors: studies on the type I receptor for IgE.

1994 • 47 citations

Transmembrane signaling by the high-affinity IgE receptor on membrane preparations.

1992 • 35 citations