Cell generation within human thymic subsets defined by selective expression of CD45 (T200) isoforms

Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.

1988 • 930 citations

Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production.

1988 • 917 citations

Human naive and memory T cells

1988 • 793 citations

Leukocyte Typing II

1986 • 688 citations

Thymus cell migration: Quantitative aspects of cellular traffic from the thymus to the periphery in mice

1980 • 551 citations

Functional subsets of human helper-inducer cells defined by a new monoclonal antibody, UCHL1.

1986 • 515 citations

The leukocyte common antigen (CD45): a putative receptor-linked protein tyrosine phosphatase.

1988 • 435 citations

Demonstration that the leukocyte common antigen (CD45) is a protein tyrosine phosphatase

1988 • 425 citations

The Developmental Biology of T Lymphocytes

1988 • 300 citations

A rapid single step staining technique for DNA analysis by flow microfluorimetry.

1980 • 294 citations

Location of T cell and major histocompatibility complex antigens in the human thymus.

1980 • 286 citations

Deletion of self-reactive thymocytes occurs at a CD4+8+ precursor stage

1988 • 265 citations

Expression and function of the CD3-antigen receptor on murine CD4+8+ thymocytes

1987 • 248 citations

Structural variants of human T200 glycoprotein (leukocyte-common antigen).

1987 • 239 citations

Loss of CD45R (Lp220) represents a post-thymic T cell differentiation event.

1988 • 218 citations

The functionally distinct subpopulations of human CD4+ helper/inducer T lymphocytes defined by anti-CD45R antibodies derive sequentially from a differentiation pathway that is regulated by activation-dependent post-thymic differentiation.

1988 • 213 citations

Developmental Status and Reconstitution Potential of Subpopulations of Murine Thymocytes

1988 • 211 citations

Intrathymic deletion of self-reactive cells prevented by neonatal anti-CD4 antibody treatment

1988 • 197 citations

Differentiation potential of subsets of CD4−8− thymocytes

1987 • 169 citations

A cd3⁻ subset of cd4⁻8⁺ thymocytes: a rapidly cycling intermediate in the generation of cd4⁺8⁺ cells

1988 • 152 citations

Identification with a monoclonal antibody of a predominantly B lymphocyte-specific determinant of the human leukocyte common antigen. Evidence for structural and possible functional diversity of the human leukocyte common molecule.

1981 • 148 citations

Differential expression of the leucocyte-common antigen family

1988 • 147 citations

Simultaneous cell cycle analysis and two-color surface immunofluorescence using 7-amino-actinomycin D and single laser excitation: applications to study of cell activation and the cell cycle of murine Ly-1 B cells.

1986 • 147 citations

The monoclonal antibody, UCHL1, recognizes a 180,000 MW component of the human leucocyte-common antigen, CD45.

1988 • 130 citations

In vivo thymocyte maturation. BUdR labeling of cycling thymocytes and phenotypic analysis of their progeny support the single lineage model.

1986 • 124 citations

Autoradiographic analysis of lymphocyte proliferation in the thymus and in thymic lymphoma tissue.

1966 • 109 citations

Definition of the thymic generative lineage by selective expression of high molecular weight isoforms of CD45 (T200)

1989 • 108 citations

Sequential events in thymocyte differentiation and thymus regeneration revealed by a combination of bromodeoxyuridine DNA labeling and antimitotic drug treatment.

1988 • 107 citations

The Developmental Biology Of T Lymphocytes

1988 • 98 citations

Immature CD4− CD8+ murine thymocytes

1988 • 93 citations

Human T cell subsets

1987 • 85 citations

Transition in CD45 isoform expression during differentiation of normal and abnormal B cells

1989 • 80 citations

Recognition and Regulation in Cell-Mediated Immunity

1985 • 79 citations

CD4+ murine T cells develop from CD8+ precursors in vivo

1987 • 71 citations

Transitions from high to low molecular weight isoforms of CD45 (T200) involve rapid activation of alternate mRNA splicing and slow turnover of surface CD45R.

1989 • 70 citations

Selective expression of CD45 isoforms and of maturation antigens during human thymocyte differentiation: observations and hypothesis

1989 • 46 citations

Developmental sequence of T200 antigen modifications in murine T cells.

1987 • 44 citations

Identification and isolation of OKT4+ suppressor cells with the monoclonal antibody WR16.

1986 • 43 citations

In situ localization of CD45 isoforms in the human thymus indicates a medullary location for the thymic generative lineage.

1990 • 42 citations

Nucleoside transport and proliferative rate in human thymocytes and lymphocytes

1989 • 37 citations

Subpopulations of CD4-CD8-murine thymocytes: differences in proliferation rate in vivo and proliferative responses in vitro

1988 • 32 citations