Recombinant human erythropoietin in the treatment of anemic patients with hematological malignancies

The Risk of Transfusion-Transmitted Viral Infections

1996 • 1,893 citations

Chemotherapy-Induced Anemia in Adults: Incidence and Treatment

1999 • 918 citations

Transfusion Medicine — Blood Transfusion

1999 • 894 citations

Diagnostic and pathogenetic considerations in transfusion‐related acute lung injury

1985 • 828 citations

Quality-of-life benefit in chemotherapy patients treated with epoetin alfa is independent of disease response or tumor type: results from a prospective community oncology study. Procrit Study Group.

1998 • 769 citations

Reports of 355 transfusion‐associated deaths: 1976 through 1985

1990 • 736 citations

Impact of therapy with epoetin alfa on clinical outcomes in patients with nonmyeloid malignancies during cancer chemotherapy in community oncology practice. Procrit Study Group.

1997 • 715 citations

Decreased Erythropoietin Response in Patients with the Anemia of Cancer

1990 • 680 citations

The Functional Assessment of Cancer Therapy-Anemia (FACT-An) Scale: a new tool for the assessment of outcomes in cancer anemia and fatigue.

1997 • 676 citations

Progress in understanding the pathogenesis of the anemia of chronic disease [see comments]

1992 • 612 citations

Effect of inflammatory cytokines on hypoxia-induced erythropoietin production

1992 • 518 citations

The suppressive influences of human tumor necrosis factors on bone marrow hematopoietic progenitor cells from normal donors and patients with leukemia: synergism of tumor necrosis factor and interferon-gamma.

1986 • 492 citations

Erythropoietin Treatment of Anemia Associated with Multiple Myeloma

1990 • 459 citations

Deleterious clinical effects of transfusion-associated immunomodulation: fact or fiction?

2001 • 422 citations

Anemia of Chronic Disorders

1984 • 419 citations

Estimated Risk of Transmission of the Human Immunodeficiency Virus by Screened Blood in the United States

1995 • 356 citations

Blood transfusion-modulated tumor recurrence: first results of a randomized study of autologous versus allogeneic blood transfusion in colorectal cancer surgery.

1994 • 347 citations

Treatment of Anemia in Myelodysplastic Syndromes With Granulocyte Colony-Stimulating Factor Plus Erythropoietin: Results From a Randomized Phase II Study and Long-Term Follow-Up of 71 Patients

1998 • 309 citations

Recombinant human erythropoietin in the anemia associated with multiple myeloma or non-Hodgkin's lymphoma: dose finding and identification of predictors of response

1995 • 226 citations

The differentiation of delayed serologic and delayed hemolytic transfusion reactions: incidence, long‐term serologic findings, and clinical significance

1990 • 225 citations

Myelofibrosis With Myeloid Metaplasia: Diagnostic Definition and Prognostic Classification for Clinical Studies and Treatment Guidelines

1999 • 219 citations

Recombinant human erythropoietin in transfusion-dependent anemic patients with multiple myeloma and non-Hodgkin's lymphoma--a randomized multicenter study. The European Study Group of Erythropoietin (Epoetin Beta) Treatment in Multiple Myeloma and Non-Hodgkin's Lymphoma

1996 • 210 citations

Monokines inhibiting erythropoietin production in human hepatoma cultures and in isolated perfused rat kidneys

1992 • 209 citations

Maintenance treatment of the anemia of myelodysplastic syndromes with recombinant human granulocyte colony-stimulating factor and erythropoietin: evidence for in vivo synergy

1996 • 209 citations

Recombinant Human Erythropoietin Therapy for Anemic Cancer Patients on Combination Chemotherapy

1993 • 207 citations

Recombinant human erythropoietin treatment in cisplatin-associated anemia: a randomized, double-blind trial with placebo.

1994 • 205 citations

Induction of hypoferremia and modulation of macrophage iron metabolism by tumor necrosis factor.

1989 • 195 citations

Prediction of response to erythropoietin treatment in chronic anemia of cancer [see comments]

1994 • 194 citations

Quality of life in chronic anemia of cancer during treatment with recombinant human erythropoietin

1994 • 171 citations

Recombinant human erythropoietin in the treatment of cancer and chemotherapy-induced anemia: results of double-blind and open-label follow-up studies.

1994 • 165 citations

Large-scale UK audit of blood transfusion requirements and anaemia in patients receiving cytotoxic chemotherapy

2000 • 163 citations

Erythropoietin for the treatment of anemia of malignancy associated with neoplastic bone marrow infiltration.

1990 • 162 citations

Inhibition of human erythroid colony-forming units by gamma interferon can be corrected by recombinant human erythropoietin [see comments]

1991 • 158 citations

Tumor necrosis factor-alpha and hematopoietic progenitors: effects of tumor necrosis factor on the growth of erythroid progenitors CFU-E and BFU-E and the hematopoietic cell lines K562, HL60, and HEL cells.

1987 • 155 citations

Regulation of transferrin receptor expression and ferritin content in human mononuclear phagocytes. Coordinate upregulation by iron transferrin and downregulation by interferon gamma.

1993 • 150 citations

Inhibition of human erythroid colony‐forming units by interleukin‐1 is mediated by gamma interferon

1992 • 147 citations

Inhibition of human erythroid colony-forming units by tumor necrosis factor requires beta interferon.

1993 • 145 citations

The anemia of chronic disease: Spectrum of associated diseases in a series of unselected hospitalized patients

1989 • 144 citations

In vivo hematopoietic effects of recombinant interleukin-1 alpha in mice: stimulation of granulocytic, monocytic, megakaryocytic, and early erythroid progenitors, suppression of late-stage erythropoiesis, and reversal of erythroid suppression with erythropoietin

1989 • 141 citations

Inhibition by interleukin-1 of the action of erythropoietin on erythroid precursors and its possible role in the pathogenesis of hypoplastic anaemias

1987 • 140 citations

The treatment of anaemia in the myelodysplastic syndromes with recombinant human erythropoietin

1991 • 131 citations

Randomized phase III trial evaluating the role of erythropoietin in the prevention of chemotherapy-induced anemia.

1997 • 129 citations

Epoetin alpha prevents anaemia and reduces transfusion requirements in patients undergoing primarily platinum-based chemotherapy for small cell lung cancer

1999 • 129 citations

Subcutaneous erythropoietin for treatment of refractory anemia in hematologic disorders. Results of a phase I/II clinical trial [see comments]

1992 • 127 citations

Treatment of chemotherapy-induced anemia with recombinant human erythropoietin in cancer patients.

1991 • 119 citations

In vivo suppression of erythropoiesis by tumor necrosis factor-alpha (TNF-alpha): reversal with exogenous erythropoietin (EPO).

1990 • 111 citations

Recombinant human erythropoietin in the treatment of chemotherapy-induced anemia and prevention of transfusion requirement associated with solid tumors: A randomized, controlled study

1998 • 110 citations

The Frequency of Red Cell Transfusion for Anemia in Patients Receiving Chemotherapy A Retrospective Cohort Study

1993 • 106 citations

Treatment of anaemia in myelodysplastic syndromes with prolonged administration of recombinant human granulocyte colony‐stimulating factor and erythropoietin

2000 • 105 citations

Association between immune activation, changes of iron metabolism and anaemia in patients with HIV infection

1993 • 102 citations

Erythropoietin treatment for chronic anemia of selected hematological malignancies and solid tumors

1993 • 98 citations

Effects of Recombinant Human Erythropoietin on the Antitumor Effect of Cisplatin in SCID Mice Bearing Human Ovarian Cancer: A Possible Oxygen Effect

1999 • 98 citations

Inadequate erythropoietin response to anemia: definition and clinical relevance

1994 • 86 citations

Cost-effectiveness of recombinant human erythropoietin in the prevention of chemotherapy-induced anaemia

1998 • 85 citations

A controlled trial of recombinant human erythropoietin after bone marrow transplantation

1994 • 82 citations

Correlation between neopterin, interferon‐gamma and haemoglobin in patients with haematological disorders

1990 • 77 citations

Cost Effectiveness, Quality-Adjusted Life-Years and Supportive Care

1999 • 71 citations

Risk Model for Severe Anemia Requiring Red Blood Cell Transfusion After Cytotoxic Conventional Chemotherapy Regimens

1999 • 71 citations

Erythropoietin plus granulocyte colony-stimulating factor in the treatment of myelodysplastic syndromes. Identification of a subgroup of responders. The Spanish Erythropathology Group.

1999 • 65 citations

What are cancer patients willing to pay for prophylactic epoetin alfa?

1998 • 65 citations

Reduced blood transfusions requirements after allogeneic bone marrow transplantation: results of a randomised, double-blind study with high-dose erythropoietin.

1994 • 65 citations

Prediction of response to optimize outcome of treatment with erythropoietin.

1998 • 58 citations

Recombinant Human Erythropoietin in the Treatment of Multiple Myeloma-Associated Anemia

1997 • 57 citations

Prediction of response to recombinant human erythropoietin (r- HuEPO/epoetin-alpha) therapy in cancer patients [letter; comment]

1995 • 57 citations

Clinical results of recombinant erythropoietin in transfusion‐dependent patients with refractory multiple myeloma: role of cytokines and monitoring of erythropoiesis

1997 • 54 citations

Erythropoietin Treatment under Polychemotherapy in Patients with Gynecologic Malignancies: A Prospective, Randomized, Double-Blind Placebo-Controlled Multicenter Study

1997 • 54 citations

Recombinant human erythropoietin for the treatment of anemia in the myelodysplastic syndromes: A clinical and erythrokinetic assessment

1992 • 52 citations

Recombinant human erythropoietin and the anemia of multiple myeloma

1993 • 52 citations

Long-term therapy with recombinant human erythropoietin (rHu-EPO) in progressing multiple myeloma

1995 • 51 citations

The effectiveness and tolerability of epoetin alfa in patients with multiple myeloma refractory to chemotherapy

1998 • 51 citations

232 Clinical and health status assessments in anaemic chronic lymphocytic leukemia (CLL) patients treated with epoetin alfa

1995 • 46 citations

Erythropoietin treatment in allogeneic BMT accelerates erythroid reconstitution: results of a prospective controlled randomized trial.

1992 • 45 citations

Macrophage control of normal and leukemic erythropoiesis: identification of the macrophage-derived erythroid suppressing activity as interleukin-1 and the mediator of its in vivo action as tumor necrosis factor

1990 • 43 citations

A randomized study of erythropoietin and granulocyte colony-stimulating factor (G-CSF) versus placebo and G-CSF for patients with Hodgkin's and non-Hodgkin's lymphoma undergoing autologous bone marrow transplantation

1994 • 41 citations

Erythropoietin reduces anemia and transfusions after chemotherapy with paclitaxel and carboplatin

1997 • 41 citations

Recombinant human erythropoietin in the treatment of cancer‐related anaemia

1997 • 40 citations

Effective treatment of disease‐related anaemia in B‐chronic lymphocytic leukaemia patients with recombinant human erythropoietin

1995 • 39 citations

Inhibition of erythropoietin production in vitro by human interferon gamma

1994 • 38 citations

Failure of combination therapy with recombinant granulocyte colony-stimulating factor and erythropoietin in myelodyspplastic syndromes

1994 • 35 citations

The risk of an overt hemolytic transfusion reaction following the use of an immediate spin crossmatch.

1990 • 31 citations

Treatment of anemia in low risk myelodysplastic syndromes with granulocyte–macrophage colony-stimulating factor plus recombinant human erythropoietin

1999 • 28 citations

Decreased affinity and number of transferrin receptors on erythroblasts in the anemia of rheumatoid arthritis

1993 • 26 citations

Subcutaneous Recombinant Human Erythropoietin for the Treatment of Anemia in Myelodysplastic Syndromes

1993 • 24 citations

Recombinant Human Erythropoietin in Patients with Myelodysplastic Syndrome and Myelofibrosis

1993 • 24 citations

Therapy with recombinant human erythropoietin in patients with myelodysplastic syndromes

1994 • 23 citations

Recombinant erythropoietin and blood transfusions in cancer chemotherapy-induced anemia

1998 • 15 citations

Recombinant Human Erythropoietin in the Treatment of Cancer-Related Anaemia

1994 • 15 citations

Combination of granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) and erythropoietin (EPO) for the treatment of advanced non‐responsive chronic lymphocytic leukemia

1999 • 9 citations

Treatment of Myelodysplastic Syndromes

2023 • 9 citations