Deficiency of TIMP-1 exacerbates LV remodeling after myocardial infarction in mice

Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction

2000 • 797 citations

Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure

1999 • 790 citations

Growth‐promoting activity of tissue inhibitor of metalloproteinases‐1 (TIMP‐1) for a wide range of cells A possible new growth factor in serum

1992 • 705 citations

Matrix Metalloproteinase Inhibition After Myocardial Infarction

2001 • 596 citations

The collagen network of the heart.

1979 • 477 citations

Regulation of collagen degradation in the rat myocardium after infarction

1995 • 469 citations

Increased Matrix Metalloproteinase Activity and Selective Upregulation in LV Myocardium From Patients With End-Stage Dilated Cardiomyopathy

1998 • 448 citations

Matrix Metalloproteinase Inhibition Attenuates Early Left Ventricular Enlargement After Experimental Myocardial Infarction in Mice

1999 • 440 citations

Integrins and the Myocardium

2001 • 439 citations

Interplay of matrix metalloproteinases, tissue inhibitors of metalloproteinases and their regulators in cardiac matrix remodeling

2000 • 426 citations

Differential Expression of Tissue Inhibitors of Metalloproteinases in the Failing Human Heart

1998 • 376 citations

Left Ventricular Remodeling in Transgenic Mice With Cardiac Restricted Overexpression of Tumor Necrosis Factor

2001 • 375 citations

Time-Dependent Changes in Matrix Metalloproteinase Activity and Expression During the Progression of Congestive Heart Failure

1998 • 372 citations

Side-to-side slippage of myocytes participates in ventricular wall remodeling acutely after myocardial infarction in rats.

1990 • 346 citations

Markers of mouse macrophage development detected by monoclonal antibodies

1994 • 345 citations

Matrix Metalloproteinase Inhibition During the Development of Congestive Heart Failure

1999 • 326 citations

Endothelial Nitric Oxide Synthase Limits Left Ventricular Remodeling After Myocardial Infarction in Mice

2001 • 313 citations

Fluvastatin, a 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitor, Attenuates Left Ventricular Remodeling and Failure After Experimental Myocardial Infarction

2002 • 309 citations

Evolution of matrix metalloprotease and tissue inhibitor expression during heart failure progression in the infarcted rat

2000 • 293 citations

Disruption of the myocardial extracellular matrix leads to cardiac dysfunction

2000 • 277 citations

In vivo murine left ventricular pressure-volume relations by miniaturized conductance micromanometry

1998 • 259 citations

Skeletal framework of mammalian heart muscle. Arrangement of inter- and pericellular connective tissue structures.

1983 • 240 citations

Echocardiographic Assessment of Left Ventricular Mass and Systolic Function in Mice

1995 • 217 citations

Selective Matrix Metalloproteinase Inhibition Reduces Left Ventricular Remodeling but Does Not Inhibit Angiogenesis After Myocardial Infarction

2002 • 187 citations

Chronic myocardial infarction in the mouse: cardiac structural and functional change

1999 • 183 citations

Role of collagen in acute myocardial infarct expansion.

1991 • 173 citations

Disruption of the Plasminogen Gene in Mice Abolishes Wound Healing after Myocardial Infarction

2000 • 149 citations

Differential effects of pressure or volume overload on myocardial MMP levels and inhibitory control

2000 • 128 citations

Effects of Gene Deletion of the Tissue Inhibitor of the Matrix Metalloproteinase-type 1 (TIMP-1) on Left Ventricular Geometry and Function in Mice

2000 • 125 citations

Age-related left ventricular function in the mouse: analysis based on in vivo pressure-volume relationships

1999 • 119 citations

Increased Amounts of Collagenase and Gelatinase in Porcine Myocardium Following Ischemia and Reperfusion

1998 • 102 citations

Estimation of parallel conductance by dual-frequency conductance catheter in mice

2000 • 83 citations

New Approaches to Phenotypic Analysis in Adult Mice

2001 • 82 citations

Development of a multifrequency conductance catheter-based system to determine LV function in mice

2000 • 57 citations

Pattern of Messenger Ribonucleic Acid Expression of Tissue Inhibitors of Metalloproteinases (TIMPs) during Testicular Maturation in Male Mice Lacking a Functional TIMP-1 Gene1

1998 • 35 citations

Decreased Expression of Tissue Inhibitor of Metalloproteinase 1 in Stunned Myocardium

1998 • 33 citations