The cyclooxygenase and lipoxygenase inhibitor BW755C protects rats against kainic acid-induced seizures and neurotoxicity

Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

1984 • 2,884 citations

Radiochemical micro assays for the determination of choline acetyltransferase and acetylcholinesterase activities

1969 • 1,043 citations

Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death

1984 • 893 citations

Electrographic, clinical and pathological alterations following systemic administration of kainic acid, bicuculline or pentetrazole: Metabolic mapping using the deoxyglucose method with special reference to the pathology of epilepsy

1981 • 654 citations

Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, and Other Derivatives of Carbon‐20 Unsaturated Fatty Acids

1982 • 580 citations

Kainic acid induced seizures: Neurochemical and histopathological changes

1983 • 526 citations

Some properties of L-glutamic decarboxylase in mouse brain

1963 • 335 citations

Mechanism of Kainate Toxicity to Cerebellar Neurons In Vitro Is Analogous to Reperfusion Tissue Injury

1987 • 334 citations

Kainic acid stimulates excitatory amino acid neurotransmitter release at presynaptic receptors

1982 • 285 citations

Effects of In Vivo Administration of Kainic Acid on the Extracellular Amino Acid Pool in the Rabbit Hippocampus

1983 • 213 citations

Excitatory Amino Acid Release from Rat Hippocampal Slices as a Consequence of Free‐Radical Formation

1988 • 210 citations

Free Arachidonic Acid and Other Lipids in the Nervous System During Early Ischemia and After Electroshock

1976 • 204 citations

Induction of brain edema following intracerebral injection of arachidonic acid

1983 • 197 citations

Microinjection of kainic acid into the rat hippocampus

1978 • 171 citations

Leukotrienes increase blood‐brain barrier permeability following intraparenchymal injections in rats

1985 • 155 citations

Excitotoxins: An Overview

1983 • 142 citations

The role of brain edema in epileptic brain damage induced by systemic kainic acid injection

1984 • 134 citations

The effects of BW755C and other anti-inflammatory drugs on eicosanoid concentrations and leukocyte accumulation in experimentally-induced acute inflammation

1983 • 132 citations

Membrane lipids in the pathogenesis of brain edema: phospholipids and arachidonic acid, the earliest membrane components changed at the onset of ischemia.

1980 • 118 citations

The accumulation of free arachidonic acid, diacylglycerols, prostaglandins, and lipoxygenase reaction products in the brain during experimental epilepsy.

1986 • 107 citations

The biochemical mechanisms of the excitotoxicity of Kainic acid

1992 • 95 citations

Effect of BW755C in an occlusion-reperfusion model of ischemic myocardial injury

1983 • 92 citations

Effect of Bicuculline‐Induced Status Epilepticus on Prostaglandins and Hydroxyeicosatetraenoic Acids in Rat Brain Subcellular Fractions

1987 • 80 citations

Idebenone attenuates neuronal degeneration induced by intrastriatal injection of excitotoxins

1990 • 80 citations

Mechanism of oxygen transfer by prostaglandin hydroperoxidase.

1980 • 73 citations

Increased prostaglandin formation in rat brain following systemic application of kainic acid

1987 • 66 citations

Effect of mannitol treatment on brain neurotransmitter markers in kainic acid-induced epilepsy

1987 • 59 citations

Inhibition of tissue damage by the arachidonate lipoxygenase inhibitor BW755C.

1984 • 42 citations

Pharmacology of free radicals; Recent views on their relation to inflammatory mechanisms

1984 • 40 citations

Inhibition of methyl chloride toxicity in male F-344 rats by the anti-inflammatory agent BW755C

1986 • 39 citations

Effects of BW755C, a mixed cyclo-oxygenase-lipoxygenase inhibitor, following traumatic spinal cord injury in rats

1988 • 35 citations

Increase in brain prostaglandins during convulsions is due to increased neuronal activity and not to hypoxia.

1983 • 29 citations

Lipid peroxidation modified the effect of phenolic anti-inflammatory drugs on prostaglandin biosynthesis

1985 • 13 citations

Oxygen free radical-induced injury in isolated rat hearts: effects of ibuprofen and BW 755c

1991 • 8 citations

Oxygen free radical-induced injury in isolated rat hearts: effects of ibuprofen and BW 755c

1991 • 6 citations

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