Early metabolic abnormalities in adolescent girls with polycystic ovarian syndrome

The Triumvirate: β-Cell, Muscle, Liver: A Collusion Responsible for NIDDM

1988 • 2,463 citations

Insulin Resistance and the Polycystic Ovary Syndrome: Mechanism and Implications for Pathogenesis*

1997 • 2,442 citations

Profound Peripheral Insulin Resistance, Independent of Obesity, in Polycystic Ovary Syndrome

1989 • 1,858 citations

Prevalence and Predictors of Risk for Type 2 Diabetes Mellitus and Impaired Glucose Tolerance in Polycystic Ovary Syndrome: A Prospective, Controlled Study in 254 Affected Women¹

1999 • 1,571 citations

Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome.

1999 • 1,269 citations

Insulin Resistance and the Polycystic Ovary Syndrome: Mechanism and Implications for Pathogenesis

1997 • 1,134 citations

Prevalence and Predictors of Risk for Type 2 Diabetes Mellitus and Impaired Glucose Tolerance in Polycystic Ovary Syndrome: A Prospective, Controlled Study in 254 Affected Women

1999 • 1,022 citations

Type 2 diabetes in children and adolescents. American Diabetes Association.

2000 • 925 citations

Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome

1992 • 908 citations

Decreases in Ovarian Cytochrome P450c17α Activity and Serum Free Testosterone after Reduction of Insulin Secretion in Polycystic Ovary Syndrome

1996 • 745 citations

A Fasting Glucose to Insulin Ratio Is a Useful Measure of Insulin Sensitivity in Women with Polycystic Ovary Syndrome¹

1998 • 688 citations

Insulin Stimulates Androgen Accumulation in Incubations of Ovarian Stroma Obtained from Women with Hyperandrogenism*

1986 • 629 citations

Insulin Stimulates Testosterone Biosynthesis by Human Thecal Cells from Women with Polycystic Ovary Syndrome by Activating Its Own Receptor and Using Inositolglycan Mediators as the Signal Transduction System¹

1998 • 571 citations

The insulin-sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome.

1996 • 538 citations

Troglitazone Improves Defects in Insulin Action, Insulin Secretion, Ovarian Steroidogenesis, and Fibrinolysis in Women with Polycystic Ovary Syndrome¹

1997 • 463 citations

Insulin secretory defects in polycystic ovary syndrome. Relationship to insulin sensitivity and family history of non-insulin-dependent diabetes mellitus.

1995 • 435 citations

Beta-cell dysfunction independent of obesity and glucose intolerance in the polycystic ovary syndrome.

1996 • 423 citations

Insulin Stimulates Testosterone Biosynthesis by Human Thecal Cells from Women with Polycystic Ovary Syndrome by Activating Its Own Receptor and Using Inositolglycan Mediators as the Signal Transduction System

1998 • 392 citations

A Fasting Glucose to Insulin Ratio Is a Useful Measure of Insulin Sensitivity in Women with Polycystic Ovary Syndrome

1998 • 354 citations

Suppression of Serum Insulin by Diazoxide Reduces Serum Testosterone Levels in Obese Women with Polycystic Ovary Syndrome*

1989 • 345 citations

TYPE 2 DIABETES MELLITUS IN MINORITY CHILDREN AND ADOLESCENTS

1999 • 280 citations

The insulin-sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome

1996 • 228 citations

Defects in beta-cell function in functional ovarian hyperandrogenism.

1993 • 225 citations

Troglitazone Improves Defects in Insulin Action, Insulin Secretion, Ovarian Steroidogenesis, and Fibrinolysis in Women with Polycystic Ovary Syndrome

1997 • 206 citations

Differences in the in vivo insulin secretion and sensitivity of healthy black versus white adolescents

1996 • 189 citations

Accelerated 24-hour luteinizing hormone pulsatile activity in adolescent girls with ovarian hyperandrogenism: relevance to the developmental phase of polycystic ovarian syndrome.

1994 • 164 citations

Metabolic features of polycystic ovary syndrome are found in adolescent girls with hyperandrogenism.

1995 • 155 citations

Beta-cell dysfunction independent of obesity and glucose intolerance in the polycystic ovary syndrome

1996 • 148 citations

Correlations Between Fatty Acid and Glucose Metabolism: Potential Explanation of Insulin Resistance of Puberty

1994 • 142 citations

Hyperinsulinemia in postpubertal girls with a history of premature pubarche and functional ovarian hyperandrogenism.

1996 • 126 citations

Testosterone Treatment in Adolescents with Delayed Puberty: Changes in Body Composition, Protein, Fat, and Glucose Metabolism¹

1997 • 122 citations

Insulin sensitivity in African-American children with and without family history of type 2 diabetes.

1999 • 119 citations

Puberty and polycystic ovarian syndrome: the insulin/insulin-like growth factor I hypothesis

1992 • 110 citations

Plasma leptin in children: Relationship to puberty, gender, body composition, insulin sensitivity, and energy expenditure

1998 • 100 citations

Testosterone Treatment in Adolescents with Delayed Puberty: Changes in Body Composition, Protein, Fat, and Glucose Metabolism

1997 • 86 citations

Defects in beta-cell function in functional ovarian hyperandrogenism

1993 • 83 citations

Type II Diabetes Mellitus: No Longer Just Adults

1999 • 73 citations

Accelerated 24-hour luteinizing hormone pulsatile activity in adolescent girls with ovarian hyperandrogenism: relevance to the developmental phase of polycystic ovarian syndrome

1994 • 66 citations

Hyperinsulinemia in postpubertal girls with a history of premature pubarche and functional ovarian hyperandrogenism

1996 • 62 citations

Metabolic features of polycystic ovary syndrome are found in adolescent girls with hyperandrogenism

1995 • 57 citations

Endocrine and Metabolic Abnormalities in Adolescents with a PCOS-like Condition: Consequences for Adult Reproduction

1998 • 55 citations

Insulin Resistance, Premature Adrenarche, and a Risk of the Polycystic Ovary Syndrome (PCOS)

1998 • 40 citations

Glucose-fatty acid interactions in prepubertal and pubertal children: effects of lipid infusion

1997 • 27 citations

Ovarian Hyperandrogenism Is Associated with Insulin Resistance to Both Peripheral Carbohydrate and Whole-Body Protein Metabolism in Postpubertal Young Females: A Metabolic Study¹

1998 • 21 citations

Ovarian Hyperandrogenism Is Associated with Insulin Resistance to Both Peripheral Carbohydrate and Whole-Body Protein Metabolism in Postpubertal Young Females: A Metabolic Study

1998 • 18 citations

Ovarian responses to hCG stimulation: insulin resistance/hyperinsulinaemia vs. insulin deficiency

1999 • 11 citations

Polycystic ovarian syndrome and associated hirsutism in the adolescent

1992 • 7 citations