Effects of phencyclidine on immediate early gene expression in the brain

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

Recent advances in the phencyclidine model of schizophrenia

1991 • 2,886 citations

The regulation and function of c-fos and other immediate early genes in the nervous system

1990 • 2,392 citations

Expression of c- fos Protein in Brain: Metabolic Mapping at the Cellular Level

1988 • 1,916 citations

Pathological Changes Induced in Cerebrocortical Neurons by Phencyclidine and Related Drugs

1989 • 1,235 citations

A Nerve Growth Factor-Induced Gene Encodes a Possible Transcriptional Regulatory Factor

1987 • 1,217 citations

Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.

1989 • 1,046 citations

NMDA Antagonist Neurotoxicity: Mechanism and Prevention

1991 • 837 citations

Continuous c-fos expression precedes programmed cell death in vivo

1993 • 784 citations

Induction of immediate-early genes and the control of neurotransmitter-regulated gene expression within the nervous system.

1995 • 685 citations

Isolation and characterization of the c-fos(rat) cDNA and analysis of post-translational modification in vitro.

1987 • 630 citations

Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts

1988 • 578 citations

A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor superfamily.

1988 • 532 citations

A gene encoding a protein with zinc fingers is activated during G0/G1 transition in cultured cells.

1988 • 428 citations

Convulsant-induced increase in transcription factor messenger RNAs in rat brain.

1988 • 377 citations

Identification of a new brain-specific transcription factor, NURR1.

1992 • 373 citations

Noncompetitive excitatory amino acid receptor antagonists

1990 • 361 citations

Lesion-induced increase in nerve growth factor mRNA is mediated by c-fos.

1990 • 314 citations

The N-methyl-d-aspartate antagonists phencyclidine, ketamine and dizocilpine as both behavioral and anatomical models of the dementias

1995 • 306 citations

Constitutive expression of zif268 in neocortex is regulated by synaptic activity.

1991 • 300 citations

Hippocampal damage and kainic acid injection induce a rapid increase in mRNA for BDNF and NGF in the rat brain

1991 • 295 citations

PCP (Phencyclidine): Historical and Current Perspectives

1982 • 260 citations

Neuronal Vacuolization and Necrosis Induced by the Noncompetitive N-methyl-d-aspartate (NMDA) Antagonist MK(+)801 (Dizocilpine Maleate): A Light and Electron Microscopic Evaluation of the Rat Retrosplenial Cortex

1993 • 257 citations

Long-term increase in the levels of c-jun mRNA and jun protein-like immunoreactivity in motor and sensory neurons following axon damage

1991 • 249 citations

Selective expression of Jun proteins following axotomy and axonal transport block in peripheral nerves in the rat: evidence for a role in the regeneration process

1991 • 235 citations

MK‐801 and ketamine induce heat shock protein HSP72 in injured neurons in posterior cingulate and retrosplenial cortex

1991 • 233 citations

EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factors.

1991 • 218 citations

Is c-Jun involved in nerve cell death following status epilepticus and hypoxic-ischaemic brain injury?

1993 • 215 citations

The early response gene NGFI-C encodes a zinc finger transcriptional activator and is a member of the GCGGGGGCG (GSG) element-binding protein family.

1991 • 201 citations

Morphine induces c-fos and junB in striatum and nucleus accumbens via D1 and N-methyl-D-aspartate receptors.

1994 • 186 citations

Seizures associated with recreational drug abuse

1989 • 184 citations

Biochemical and behavioral effects of sigma and PCP ligands

1988 • 176 citations

Regulation of nerve growth factor biosynthesis by beta-adrenergic receptor activation in astrocytoma cells: a potential role of c-Fos protein.

1989 • 149 citations

Induction and suppression of immediate early genes in specific rat brain regions by the non-competitive N-methyl-d-aspartate receptor antagonist MK-801

1993 • 137 citations

Detection of fos protein during osteogenesis by monoclonal antibodies.

1988 • 123 citations

c-fos expression and (14C) 2-deoxyglucose uptake in the caudal cerebellum of the rat during motor/sensory cortex stimulation

1989 • 121 citations

Differential expression of immediate early genes after transection of the facial nerve

1993 • 117 citations

Haloperidol prevents induction of the hsp70 heat shock gene in neurons injured by phencyclidine (PCP), MK801, and ketamine

1992 • 106 citations

Temporal and Spatial Patterns of Expression of c-fos, zif/268, c-jun and jun-B mRNAs in Rat Brain Following Seizures Evoked Focally from the Deep Prepiriform Cortex

1993 • 77 citations

Cerebellar toxicity of phencyclidine

1995 • 67 citations

Delayed regional metabolic actions of phencyclidine

1993 • 67 citations

MK801 induces immediate-early gene proteins and BDNF mRNA in rat cerebrocortical neurones

1993 • 65 citations

Focal brain injury induces multiple immediate early genes encoding zinc finger transcription factors

1995 • 62 citations

Drugs Acting on σ and Phencyclidine Receptors

1989 • 61 citations

Transient c-fos expression accompanies naturally occurring cell death in the developing interhemispheric cortex of the rat

1992 • 60 citations

Early response genes as markers of neuronal activity and growth factor action.

1993 • 48 citations

Axotomy-induced regulation of c-Jun expression in regenerating rat retinal ganglion cells

1995 • 46 citations

Allosteric Modulation of N-Methyl-D-Aspartate Receptors

1990 • 43 citations

The convulsant and anticonvulsant effects of phencyclidine (PCP) and PCP analogues in the rat

1986 • 40 citations

Hyperglycemia Suppresses c-FosmRNA Expression following Transient Cerebral Ischemia in Gerbils

1992 • 32 citations

FOS expression in the brainstem and cerebellum following phencyclidine and MK801

1996 • 32 citations

A rat model of phencyclidine psychosis

1994 • 29 citations

Apoptosis in the nervous system: new revelations.

1995 • 23 citations

Opposite effects of axon damage on heat shock proteins (hsp 70) and ubiquitin contents in motor neurons of neuropathic rats

1993 • 13 citations

Antagonism of phencyclidine-induced hyperactivity in mice by elevated brain GABA concentrations

1992 • 10 citations