Neurotoxic acylpolyamines from spider venoms

Biophilia

1984 • 2,603 citations

The Role of Glutamate Neurotoxicity in Hypoxic-Ischemic Neuronal Death

1990 • 2,204 citations

Diversity and ubiquity of K channels

1988 • 1,342 citations

Neurotoxins that Act on Voltage-Sensitive Sodium Channels in Excitable Membranes

1980 • 1,236 citations

P-type calcium channels blocked by the spider toxin ω-Aga-IVA

1992 • 877 citations

Selective vulnerability of the hippocampus in brain ischemia

1991 • 876 citations

Blocking and isolation of a calcium channel from neurons in mammals and cephalopods utilizing a toxin fraction (FTX) from funnel-web spider poison.

1989 • 631 citations

The Nicotinic Cholinergic Receptor: Correlation of Molecular Structure with Functional Properties

1982 • 456 citations

Excitatory amino acid transmission

1987 • 430 citations

Excitotoxic mechanisms of epileptic brain damage.

1986 • 389 citations

The role of NMDA receptors in learning and memory

1987 • 360 citations

Toxins: Animal, plant and microbial.

1978 • 274 citations

Purification from black widow spider venom of a protein factor causing the depletion of synaptic vesicles at neuromuscular junctions.

1976 • 236 citations

The neuroexcitotoxic amino acids glutamate and aspartate are altered in the spinal cord and brain in amyotrophic lateral sclerosis

1988 • 210 citations

Structure and synthesis of a potent glutamate receptor antagonist in wasp venom.

1988 • 201 citations

Metabolic factors during prolonged seizures and their relation to nerve cell death.

1983 • 192 citations

Glutamate transmission and toxicity in alzheimer's disease

1988 • 190 citations

Black Widow Spider Venom: Effect of Purified Toxin on Lipid Bilayer Membranes

1976 • 186 citations

Toxins of Animal and Plant Origin

1973 • 171 citations

Spider venom contains specific receptor blocker of glutaminergic synapses

1982 • 169 citations

Purification and Characterization of Two Classes of Neurotoxins from the Funnel Web Spider, Agelenopsis aperta

1989 • 167 citations

The biology of spiders.

1992 • 152 citations

Platelet aggregation and sphingomyelinase D activity of a purified toxin from the venom of loxosceles reclusa

1981 • 152 citations

Omega-agatoxins: novel calcium channel antagonists of two subtypes from funnel web spider (Agelenopsis aperta) venom.

1990 • 125 citations

The NMDA receptor: central role in pain inhibition in rat periaqueductal gray

1988 • 118 citations

Chemical characterization of spider toxin, JSTX and NSTX.

1986 • 111 citations

Two classes of channel-specific toxins from funnel web spider venom

1989 • 108 citations

Cloning and structure of cDNA encoding α‐latrotoxin from black widow spider venom

1990 • 108 citations

Isolation of neurotoxic peptides from the venom of the ‘armed’ spider Phoneutria nigriventer

1991 • 107 citations

Spider toxins affecting glutamate receptors: Polyamines in therapeutic neurochemistry

1991 • 103 citations

Inhibition of N- and L-type Ca2+ channels by the spider venom toxin omega-Aga-IIIA.

1991 • 98 citations

Structures and biological activities of three synaptic antagonists from orb weaver spider venom

1987 • 98 citations

Isolation, structure elucidation, and synthesis of novel hydroxylamine-containing polyamines from the venom of the Agelenopsis aperta spider

1990 • 96 citations

Hyaluronidase and esterase activities of the venom of the poisonous brown recluse spider

1973 • 92 citations

Preparation and properties of a neurotoxin purified from the venom of black widow spider (Latrodectus mactans tredecimguttatus)

1976 • 89 citations

Neurotoxins from Plectreurys spider venom are potent presynaptic blockers in Drosophila

1987 • 86 citations

Curtatoxins. Neurotoxic insecticidal polypeptides isolated from the funnel-web spider Hololena curta.

1990 • 86 citations

Postsynaptic block of a glutamatergic synapse by low molecular weight fractions of spider venom

1985 • 81 citations

Complete amino acid sequence of a new type of lethal neurotoxin from the venom of the funnel‐web spider Atrax robustus

1985 • 81 citations

Amino acid sequence of versutoxin, a lethal neurotoxin from the venom of the funnel-web spider Atrax versutus

1988 • 77 citations

Spider toxins selectively block calcium currents in drosophila

1989 • 77 citations

ω‐Aga‐I: A presynaptic calcium channel antagonist from venom of the funnel web spider, Agelenopsis aperta

1989 • 76 citations

Evidence for distinct sites coupled to high affinity ω-conotoxin receptors in rat brain synaptic plasma membrane vesicles

1988 • 76 citations

Antagonism of synaptosomal calcium channels by subtypes of omega-agatoxins.

1992 • 74 citations

Isolation and structure analysis of components from venom of the spider Argiope lobata

1989 • 68 citations

Separation of three toxicologically different protein components from the venom of the spider Latrodectus tredecimguttatus

1964 • 64 citations

Synthesis of spider toxin (JSTX-3) and its analogs

1987 • 64 citations

Mode of action of Phoneutria nigriventer spider venom at the isolated phrenic nerve-diaphragm of the rat.

1985 • 62 citations

Selective presynaptic insectotoxin (α-latroinsectotoxin) isolated from black widow spider venom

1992 • 62 citations

Composition and properties of tarantula Dugesiella hentzi (Girard) venom

1973 • 62 citations

Funnel-web spider venom and a toxin fraction block calcium current expressed from rat brain mRNA in Xenopus oocytes.

1990 • 60 citations

Dermonecrotic and lethal components of Loxosceles gaucho spider venom

1992 • 60 citations

Isolation and characterization of toxins from brown recluse spider venom (Loxosceles reclusa)

1976 • 59 citations

Isolation and characterisation of glutamate receptor antagonists from venoms of orb-web spiders

1988 • 59 citations

Paralytic and insecticidal toxins from the funnel web spider, Hololena curta

1991 • 58 citations

The purification and amino acid sequence of the lethal neurotoxin Tx1 from the venom of the Brazilian ‘armed’ spider Phoneutria nigriventer

1990 • 58 citations

Properties of Calcium Channels Isolated with Spider Toxin, FTX

1991 • 58 citations

Tarantula(Eurypelma californicum)Venom, a Multicomponent System

1989 • 55 citations

Structure of paralytic acylpolyamines from the spider Agelenopsisaperta

1990 • 55 citations

Identification of insecticidal peptides from venom of the trap-door spider, Aptostichus schlingeri (Ctenizidae)

1992 • 55 citations

Comparative lethality of several Latrodectus venoms

1964 • 53 citations

Identification and purification of an irreversible presynaptic neurotoxin from the venom of the spider Hololena curta.

1987 • 50 citations

Adenosine triphosphate in tarantula spider venoms and its synergistic effect with the venom toxin

1975 • 50 citations

EFFECTS OF PHONEUTRIA NIGRIVENTER SPIDER VENOM ON MOUSE PERIPHERAL NERVE

1985 • 47 citations

Enzymatic and hemolytic properties of brown recluse spider (Loxosceles reclusa) toxin and extracts of venom apparatus, cephalothorax and abdomen

1983 • 47 citations

Inhibition of neuronal Ca2+ channel currents by the funnel web spider toxin omega-Aga-IA.

1990 • 46 citations

A Toxin Purified from the Venom of Black Widow Spider Affects the Uptake and Release of Radioactive γ‐Amino Butyrate and N‐Epinephrine from Rat Brain Synaptosomes

1979 • 46 citations

Chemical characterization of acylpolyamine toxins from venom of a trap-door spider and two tarantulas

1990 • 45 citations

<b>CHEMICAL STRUCTURE OF JORO SPIDER TOXIN </b><b>(JSTX) </b>

1987 • 44 citations

<b>A new type of spider toxin, Nephilatoxin, in the venom of the Joro spider, <i>Nephila </i></b><b><i>clavata </i></b>

1988 • 43 citations

The total synthesis of argiotoxins 636, 659 and 673

1988 • 43 citations

Synthesis of a new neurotoxin NSTX-3 of Papua New Guinean spider

1987 • 42 citations

<b>ISOLATION AND CHEMICAL CHARACTERIZATION OF A SERIES OF NEW SPIDER TOXIN (NEPHILATOXINS) IN THE VENOM OF JORO SPIDER, <i>NEPHILA </i></b><b><i>CLAVATA </i></b>

1988 • 40 citations

Novel quaternary ammonium salt-containing polyamines from the Agelenopsis aperta funnel-web spider

1992 • 39 citations

Serum amyloid P component: its role in platelet activation stimulated by sphingomyelinase D purified from the venom of the brown recluse spider (Loxosceles reclusa)

1990 • 39 citations

Characteristics of an alkaline phosphatase activity in brown recluse venom

1974 • 39 citations

Structure of the low molecular weight protein copurified with α-latrotoxin

1992 • 39 citations

<b>CHEMICAL CHARACTERIZATION OF SPIDER TOXIN, </b><b>NSTX </b>

1987 • 38 citations

[44] Overview of toxins and drugs as tools to study excitable membrane ion channels: II. Transmitter-activated channels

1992 • 37 citations

Die Giftsekrete der Vogelspinnen

1957 • 36 citations

The total synthesis of argiopine (argiotoxin-636)

1987 • 36 citations

Separation and characterization of venom components in Loxosceles reclusa—III. Hydrolytic enzyme activity

1979 • 33 citations

Purification and characterization of tarantula, Dugesiella hentzi (girard) venom Hyaluronidase

1973 • 33 citations

Phoneutria nigriventer Venom—Pharmacology and Biochemistry of Its Components

1971 • 33 citations

An Investigation of Certain Components of the Venom of the Female Sydney Funnel Web Spider, Atrax Robustus Cambr.

1964 • 33 citations

Purification and characterization of a toxin from brown recluse spider (Loxosceles reclusa) venom gland extracts

1981 • 32 citations

Isolation of a pure toxic polypeptide from the venom of the spider Phoneutria nigriventer and its neurophysiological activity on an insect femur preparation

1982 • 32 citations

OBSERVATIONS ON THE VENOM OF THE SYDNEY FUNNEL‐WEB SPIDER (ATRAX ROBUSTUS)

1961 • 31 citations

Venoms of Theridiidae, Genus Latrodectus

1978 • 30 citations

Composition and properties of extract of fiddleback (Loxosceles reclusa) spider venom apparatus

1973 • 30 citations

<b>COMPLETE AMINO ACID SEQUENCE OF A NEW TYPE OF NEUROTOXIN FROM THE VENOM OF THE SPIDER, <i>AGELENA</i> <i>OPULENT</i></b><b><i>A </i></b>

1990 • 30 citations

[43] Overview of toxins and drugs as tools to study excitable membrane ion channels: I. Voltage-activated channels

1992 • 30 citations

Antagonism of glutamate receptor channel complexes by spider venom polypeptides.

1985 • 29 citations

Polyamines in some tarantula venoms

1980 • 29 citations

The purification and characterization of a necrotoxin from tarantula, Dugesiella hentzi (Girard), venom

1974 • 28 citations

An immunological and electrophoretical comparison of the venoms of the North American Latrodectus spiders

1965 • 27 citations

Pharmacology of the polypeptides from the venom of the spider Phoneutria fera.

1966 • 27 citations

Separation and characterization of venom components in Loxosceles reclusa—II. Protease enzyme activity

1979 • 27 citations

ISOLATION AND CHARACTERIZATION OF A LETHAL COMPONENT FROM THE VENOM OF LATRODECTUS MACTANS MACTANS

1967 • 27 citations

Toxins that affect voltage-dependent calcium channels

1987 • 24 citations

Venoms of Dipluridae

1978 • 24 citations

Phosphodiesterase of some snake and arthropod venoms

1966 • 24 citations

Animal and plant toxins

2010 • 24 citations

Isolation of a neurotoxin with a presynaptic action from the venom of the black widow spider (Latrodectus mactans, Fabr.)

1976 • 23 citations

Venoms of Scytodidae. Genus Loxosceles

1978 • 23 citations

Spiders of the World

1984 • 23 citations

Studies of the necrotic actions of the venoms of several australian spiders

1991 • 23 citations

Characterization and some properties of the venom gland extract of a theridiid spider (Steatoda paykulliana) frequently mistaken for black widow spider (Latrodectus tredecimguttatus)

1987 • 23 citations

Analysis of the venom of the sydney funnel-web spider,Atrax robustus using gas chromatography mass spectrometry

1979 • 22 citations

Spider Venoms: Biochemical Aspects

1969 • 22 citations

Total synthesis of nstx-3, spider toxin of nephila maculata

1991 • 21 citations

Anticonvulsant action of an arylamine-containing fraction fromAgelenopsis spider venom

1990 • 21 citations

Total synthesis of clavamine, insecticidally active compound isolated from venom of joro spider (Nephila Clavata)

1990 • 20 citations

Postsynaptic blocking of glutamatergic and cholinergic synapses as a common property of Araneidae spider venoms

1985 • 20 citations

Partial characterization of the low molecular weight fractions of the extract of the venom apparatus of the brown recluse spider and of its hemolymph

1975 • 19 citations

Venoms of Ctenidae

1978 • 19 citations

Die Giftsekrete der brasilianischen TarantelLycosa erythrognathaund der WanderspinnePhoneutria fera

1957 • 19 citations

Synthesis of neurotoxic nephila spider venoms: NSTX-3 and JSTX-3

1989 • 19 citations

Action of black widow spider venom at insect neuromuscular junctions

1973 • 18 citations

The components of the venom of a spider Scodra griseipes. 1. Analysis of low molecular weight products using gas chromatography/mass spectrometry

1992 • 18 citations

Synthetic studies on spider neurotoxins (I): total synthesis of nephilatoxins (NPTX-9) and NPTX-11), new neurotoxins of Joro spider (Nephila clavata)

1992 • 18 citations

Structure-activity relationship of NSTX-3, spider toxin of nephila maculata

1990 • 18 citations

Biochemical analysis of tarantula venom (Eurypelma californicum)

1989 • 17 citations

Effects of Different Spider Venoms on Artificial and Biological Membranes

1983 • 15 citations

A study of the necrotic actions of the venom of the wolf spider, Lycosa godeffroyi, on mouse skin

1990 • 15 citations

Inactivation of Complement by Loxosceles Reclusa Spider Venom

1979 • 15 citations

Immunological Studies of Brown Recluse Spider Venom

1974 • 14 citations

5-hydroxytryptamine content of Latrodectus mactans tredecimguttatus venom from gland extracts

1972 • 14 citations

The isolation and N-terminal sequence of the lethal neurotoxin from the venom of the male Sydney funnel web spider,

1983 • 14 citations

Partial characterization of lethal and neuroactive components of the brown recluse spider (Loxosceles reclusa) venom

1979 • 14 citations

Molecular structures of spider toxins (JSTX-1, 2, 3 and 4) in the venom of Nephila clavata L. Koch

1990 • 13 citations

The components of the venom of a spider Scodra griseipes. 2. Structural information on biogenic amines using tandem mass spectrometry

1992 • 13 citations

Loxosceles laeta venom—Partial purification

1971 • 13 citations

THE SYDNEY FUNNEL–WEB SPIDER (ATRAX ROBUSTUS) 2. FRACTIONATION OF THE FEMALE VENOM INTO FIVE DISTINCT COMPONENTS

1972 • 12 citations

Isolation and characterization of a protein neurotoxin from the venom glands of the funnel-web spider (Atrax robustus)

1983 • 11 citations

Glutamatergic postsynaptic block by Pamphobeteus spider venoms in crayfish

1992 • 11 citations

THE SYDNEY FUNNEL–WEB SPIDER ( ATRAX ROBUSTUS ): 1: A REVIEW OF PUBLISHED STUDIES ON THE CRUDE VENOM

1972 • 11 citations

[A crustacean-specific neurotoxin from the venom of the black widow spider Latrodectus mactans tredecimguttatus].

1990 • 11 citations

APHONOPELMA TARANTULA VENOM

1967 • 10 citations

A new insecticide, clavamine, from venom of a spider, Nephila clavata - I. Purification and identification of the structure.

1990 • 10 citations

Synthetic studies on spider neurotoxins (II): Total synthesis of nephilatoxins (NPTX-10 and NPTX-12), new neurotoxins of Joro spider (Nephila clavata)

1992 • 10 citations

Gel electrophoresis: a tool in systematics. Studies with Latrodectus mactans venom

1970 • 10 citations

Separation and characterization of venom components in the brown recluse spider (Loxosceles reclusa) — I. Preparative disc electrophoresis

1979 • 10 citations

Spastic action of the venom of the spider Phoneutria fera.

1955 • 8 citations

[Identification and isolation of the protein insect toxin (alpha-latroinsectotoxin from venom of the spider Latrodectus mactans tredecimguttatus].

1990 • 7 citations

[Toxic components of the venom of the cellar spider Segestria florentina].

1987 • 6 citations

Electrophoresis And Electrofocusing of Venom of Loxosceles Reclusa Gertsch & Mulaik (Araneida: Scytodidae)1

1976 • 6 citations

Determination of biogenic amines in spider venom glands of nine typical Japanese species and chromatographic elution pattern analysis of venomous components

1991 • 6 citations

Isolation and partial characterization of a toxin from the venom of the East African orthognath spider Pterinochilus spec.

1982 • 6 citations

[Kininase isolation from the venom of spider Latrodectus tredecimguttatus].

1981 • 6 citations

Neurotoxic Action of the Venom of the Common American House Spider

1984 • 5 citations

[Isolation and characteristics of the neurotoxin from the spider Segestria florentina].

1985 • 5 citations

[Isolation and quaternary structure of the neurotoxin from the venom of the spider Latrodectus tredecimguttatus].

1982 • 5 citations

Beitrag zur Kenntnis des Spinnengiftes vonLatrodectus tredecimguttatusRossi

1956 • 4 citations

Protein Components of Loxosceles reclusa Venom

1967 • 4 citations

Venomous and poisonous animals and noxious plants of the pacific region

1965 • 3 citations

Isolation and Study of the Properties of Kininase from the Venom of Spider Latrodectus Tredecimguttatus

1989 • 3 citations

[Isolation of cholinesterase from the venom of the spider Latrodectus tredecimguttatus and the study of its properties].

1983 • 2 citations

Loxosceles reclusa venom component toxicity and interaction in Musca domestica

1980 • 1 citations

[Channel-forming action--a general property of venoms of spiders in the family Theridiidae (Aranei)].

1985 • 1 citations

Bradykinin-potentiating peptide from venom of the spider Latrodectus tredecimguttatus

1989 • 1 citations

Deleted Work

1955 • 0 citations