Down but not out? A novel protein isoform of the estrogen receptor alpha is expressed in the estrogen receptor alpha knockout mouse

Cloning of a novel receptor expressed in rat prostate and ovary.

1996 • 4,782 citations

Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

1999 • 1,965 citations

Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene.

1993 • 1,836 citations

Generation and reproductive phenotypes of mice lacking estrogen receptor β

1998 • 1,680 citations

Effect of single and compound knockouts of estrogen receptors α (ERα) and β (ERβ) on mouse reproductive phenotypes

2000 • 1,026 citations

A role for oestrogens in the male reproductive system

1997 • 872 citations

Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen.

1990 • 772 citations

Estrogens as a cause of human cancer: the Richard and Hinda Rosenthal Foundation award lecture.

1988 • 703 citations

A versatilein vivoandin vitroeukaryotic expression vector for protein engineering

1988 • 686 citations

TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice

1993 • 659 citations

Postnatal Sex Reversal of the Ovaries in Mice Lacking Estrogen Receptors α and β

1999 • 583 citations

Modifier genes in mice and humans

2001 • 569 citations

Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

1999 • 526 citations

Antiestrogen ICI 164,384 reduces cellular estrogen receptor content by increasing its turnover.

1992 • 468 citations

Cytokines and Estrogen in Bone: Anti-Osteoporotic Effects

1993 • 466 citations

Immunochemical studies of estrogen receptors

1984 • 439 citations

Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene.

1995 • 428 citations

The Human Estrogen Receptor-α Is a Ubiquitinated Protein Whose Stability Is Affected Differentially by Agonists, Antagonists, and Selective Estrogen Receptor Modulators

2001 • 422 citations

Identification of a new isoform of the human estrogen receptor-alpha (hER-alpha) that is encoded by distinct transcripts and that is able to repress hER-alpha activation function 1

2000 • 405 citations

Physiological coupling of growth factor and steroid receptor signaling pathways: estrogen receptor knockout mice lack estrogen-like response to epidermal growth factor.

1996 • 305 citations

Requirement of Estrogen Receptor-α in Insulin-like Growth Factor-1 (IGF-1)-induced Uterine Responses and in Vivo Evidence for IGF-1/Estrogen Receptor Cross-talk

2002 • 282 citations

Haploinsufficient Phenotypes inBmp4Heterozygous Null Mice and Modification by Mutations inGli3andAlx4

1997 • 282 citations

BMP7 Acts in Murine Lens Placode Development

1999 • 272 citations

Regulation of Estrogen Receptor Messenger Ribonucleic Acid and Protein Levels in Human Breast Cancer Cell Lines by Sex Steroid Hormones, Their Antagonists, and Growth Factors

1989 • 261 citations

Characterization of the Amino-terminal Transcriptional Activation Function of the Human Estrogen Receptor in Animal and Yeast Cells

1995 • 230 citations

The Mechanism of ICI 164,384 Antiestrogenieity Involves Rapid Loss of Estrogen Receptor in Uterine Tissue

1991 • 201 citations

Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene

1995 • 187 citations

The AF-1 activation-function of ERα may be dispensable to mediate the effect of estradiol on endothelial NO production in mice

2002 • 171 citations

Two Separate Mechanisms for Ligand-Independent Activation of the Estrogen Receptor

1997 • 153 citations

Telomere shortening in mTR-/- embryos is associated with failure to close the neural tube

1999 • 142 citations

Sex determination and sex differentiation

2002 • 69 citations

Minimal Phenotype of Mice Homozygous for a Null Mutation in the Forkhead/Winged Helix Gene, Mf2

2000 • 55 citations

Purification and Characterization of Mouse Uterine Estrogen Receptor under Conditions of Varying Hormonal Status

1987 • 48 citations

10 The oestrogen receptor

1994 • 29 citations

Estrogenic and Antiestrogenic Down-regulation of Estrogen Receptor Levels: Evidence for two Different Mechanisms

1990 • 24 citations

Estrogens and Progestins

2014 • 24 citations