Participation of both intracellular free Ca2+ and protein kinase C in tonic vasoconstriction induced by prostaglandin F2α

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

1982 • 2,255 citations

Regulation and Kinetics of the Actin-Myosin-ATP Interaction

1980 • 1,077 citations

Calcium-mobilizing receptors, polyphosphoinositides, and the generation of second messengers.

1986 • 831 citations

Myosin Phosphorylation and the Cross-Bridge Cycle in Arterial Smooth Muscle

1981 • 705 citations

Calcium-dependent protein kinase: widespread occurrence in various tissues and phyla of the animal kingdom and comparison of effects of phospholipid, calmodulin, and trifluoperazine.

1980 • 568 citations

Metabolism of inositol 1,4,5-trisphosphate and inositol 1,3,4-trisphosphate in rat parotid glands

1985 • 450 citations

Inositol 1,4,5-trisphosphate releases Ca2+ from intracellular store sites in skinned single cells of porcine coronary artery

1984 • 389 citations

STUDIES ON THE MECHANISM OF ACTION OF A NEW Ca²⁺ ANTAGONIST, 8‐(N,N‐DIETHYLAMINO)OCTYL 3,4,5‐TRIMETHOXYBENZOATE HYDROCHLORIDE IN SMOOTH AND SKELETAL MUSCLES

1975 • 347 citations

Studies of the characterisation of prostanoid receptors: A proposed classification

1982 • 305 citations

TPA-induced contraction of isolated rabbit vascular smooth muscle

1984 • 266 citations

Phorbol ester and 1-oleoyl-2-acetylglycerol inhibit angiotensin activation of phospholipase C in cultured vascular smooth muscle cells.

1985 • 240 citations

Phorbol ester-induced contraction of arterial smooth muscle and inhibition of α-adrenergic response

1984 • 216 citations

Phosphatidylinositol-4,5-bisphosphate phosphodiesterase and phosphomonoesterase activities of rat brain. Some properties and possible control mechanisms

1984 • 194 citations

Angiotensin II rapidly increases phosphatidate-phosphoinositide synthesis and phosphoinositide hydrolysis and mobilizes intracellular calcium in cultured arterial muscle cells.

1984 • 159 citations

5-Hydroxytryptamine2 receptors coupled to phospholipase C in rat aorta: modulation of phosphoinositide turnover by phorbol ester.

1986 • 141 citations

Calcium and cardiovascular function

1984 • 129 citations

Carbachol causes rapid phosphodiesteratic cleavage of phosphatidylinositol 4,5-bisphosphate and accumulation of inositol phosphates in rabbit iris smooth muscle; prazosin inhibits noradrenaline- and ionophore A23187-stimulated accumulation of inositol phosphates

1984 • 97 citations

Phorbol ester contracts rabbit thoracic aorta by increasing intracellular calcium and by activating calcium influx

1986 • 91 citations

Effects of prostaglandins and oxytocin on calcium release from a uterine microsomal fraction.

1977 • 87 citations

Cerebrovascular actions of prostaglandins

1982 • 85 citations

Protein kinase C-activated calcium channel in the osteoblast-like clonal osteosarcoma cell line UMR-106.

1987 • 80 citations

Dissociation of myosin phosphorylation and active tension during muscarinic stimulation of tracheal smooth muscle.

1987 • 78 citations

Effects of prostaglandins on the cytosolic free calcium concentration in vascular smooth muscle cells

1986 • 69 citations

Ca++ utilization in the constriction of rat aorta to stimulation of protein kinase C by phorbol dibutyrate.

1987 • 44 citations

Effects of a phorbol ester on rat aortic contraction and calcium influx in the presence and absence of BAY k 8644

1987 • 41 citations

Prostaglandins activate phosphoinositide metabolism in rat aorta

1987 • 37 citations

1-oleoyl-2-acetyl-glycerol and phorbol diester stimulate Ca2+ influx through Ca2+ channels in neuroblastoma × glioma hybrid NG108-15 cells

1986 • 29 citations