Nopaline causes a conformational change in the NocR regulatory protein-nocR promoter complex of Agrobacterium tumefaciens Ti plasmid pTiT37

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes.

1987 • 5,066 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

Experiments With Gene Fusions

1984 • 2,487 citations

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

Supercoiling of the DNA template during transcription.

1987 • 1,909 citations

Experiments with gene fusions

1985 • 1,210 citations

XL1-Blue: a high efficiency plasmid transforming recA Escherichia coli strain with beta-galactosidase selection.

1987 • 1,190 citations

THE CHEMISTRY AND BIOLOGY OF LEFT-HANDED Z-DNA

1984 • 1,149 citations

DNA Topoisomerases

1981 • 977 citations

Transcriptional Regulator of Oxidative Stress-Inducible Genes: Direct Activation by Oxidation

1990 • 869 citations

Large plasmid in Agrobacterium tumefaciens essential for crown gall-inducing ability

1974 • 736 citations

A structural taxonomy of DNA-binding domains

1991 • 615 citations

A large family of bacterial activator proteins.

1988 • 559 citations

The three operators of the lac operon cooperate in repression.

1990 • 487 citations

Regulation of ribosomal RNA promoters with a synthetic lac operator.

1984 • 451 citations

The functional organization of the nopaline A. tumefaciens plasmid pTiC58

1980 • 447 citations

A Tn3 lacZ transposon for the random generation of beta-galactosidase gene fusions: application to the analysis of gene expression in Agrobacterium.

1985 • 421 citations

OxyR, a positive regulator of hydrogen peroxide-inducible genes in Escherichia coli and Salmonella typhimurium, is homologous to a family of bacterial regulatory proteins.

1989 • 415 citations

lac repressor forms loops with linear DNA carrying two suitably spaced lac operators.

1987 • 353 citations

Octopine and nopaline synthesis and breakdown genetically controlled by a plasmid of Agrobacterium tumefaciens

1976 • 320 citations

Unusual DNA structures.

1988 • 309 citations

Molecular Biology of Plant Tumors

1982 • 286 citations

The MerR heavy metal receptor mediates positive activation in a topologically novel transcription complex

1989 • 286 citations

Unusual DNA Structures

2011 • 277 citations

T-DNA from Agrobacterium Ti plasmid is in the nuclear DNA fraction of crown gall tumor cells

1980 • 259 citations

Action at a Distance Along a DNA

1988 • 220 citations

Divergent promoters, a common form of gene organization

1988 • 195 citations

Allosteric underwinding of DNA is a critical step in positive control of transcription by Hg-MerR

1992 • 187 citations

Isolation of Agrobacterium Ti-plasmid regulatory mutants

1978 • 149 citations

The functional organization of the octopine Agrobacterium tumefaciens plasmid pTiB6S3

1981 • 148 citations

The A. tumefaciens transcriptional activator OccR causes a bend at a target promoter, which is partially relaxed by a plant tumor metabolite

1992 • 136 citations

Interaction of the plasmid R6K-encoded replication initiator protein with its binding sites on DNA

1983 • 136 citations

Sites of reaction of Escherichia coli DNA gyrase on pBR322 in vivo as revealed by oxolinic acid-induced plasmid linearization

1985 • 117 citations

DNA distortion accompanies transcriptional activation by the metal-responsive gene-regulatory protein MerR

1990 • 116 citations

Conformational changes in a replication origin induced by an initiator protein

1985 • 115 citations

Regulation of diaminopimelate decarboxylase synthesis in Escherichia coli

1983 • 95 citations

Homologous metalloregulatory proteins from both gram-positive and gram-negative bacteria control transcription of mercury resistance operons

1989 • 82 citations

Demonstration, characterization, and mutational analysis of NahR protein binding to nah and sal promoters

1989 • 81 citations

Identification of the nahR gene product and nucleotide sequences required for its activation of the sal operon

1986 • 80 citations

Divergent promoters, a common form of gene organization.

1988 • 79 citations

The cysP promoter of Salmonella typhimurium: characterization of two binding sites for CysB protein, studies of in vivo transcription initiation, and demonstration of the anti-inducer effects of thiosulfate

1991 • 78 citations

Transcription of the Octopine Catabolism Operon of theAgrobacteriumTumor-Inducing Plasmid pTiA6 Is Activated by a LysR-Type Regulatory Protein

1991 • 75 citations

The roles of indoleglycerol phosphate and the Trpl protein in the expression oftrpBA fromPseudomonas aeruginosa

1990 • 65 citations

Opine Utilization by Agrobacterium

1982 • 57 citations

Occurrence and Biosynthesis of Opines

1982 • 57 citations

Transcription-induced conformational change in a topologically closed DNA domain

1991 • 49 citations

Inducible Permease Involved in the Uptake of Octopine, Lysopine and Octopinic Acid by Agrobacterium tumefaciens Strains Carrying Virulence-associated Plasmids

1977 • 49 citations

RNA polymerase and gal repressor bind simultaneously and with DNA bending to the control region of the Escherichia coli galactose operon.

1989 • 44 citations

Characterization of a putative periplasmic transport system for octopine accumulation encoded by Agrobacterium tumefaciens Ti plasmid pTiA6

1991 • 39 citations

Positive Regulators of Opine-Inducible Promoters in the Nopaline and Octopine Catabolism Regions of Ti Plasmids

1991 • 37 citations

In vitro determination of the effect of indoleglycerol phosphate on the interaction of purified TrpI protein with its DNA-binding sites

1991 • 35 citations

Transport of nonmetabolizable opines by Agrobacterium tumefaciens

1991 • 17 citations

Ti plasmid and chromosomal ornithine catabolism genes of Agrobacterium tumefaciens C58

1983 • 17 citations