Pedigree disequilibrium test (PDT) replicates association and linkage between DRD4 and ADHD in multigenerational and extended pedigrees from a genetic isolate

Performing the Exact Test of Hardy-Weinberg Proportion for Multiple Alleles

1992 • 4,934 citations

Wechsler Abbreviated Scale of Intelligence

1999 • 4,478 citations

Genetic Dissection of Complex Traits

1994 • 3,497 citations

The Composite International Diagnostic Interview

1988 • 2,832 citations

Strategies for multilocus linkage analysis in humans.

1984 • 2,600 citations

A continuous performance test of brain damage.

1956 • 2,206 citations

PedCheck: A Program for Identification of Genotype Incompatibilities in Linkage Analysis

1998 • 2,089 citations

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

1991 • 2,008 citations

Diagnostic Interview for Genetic Studies

1994 • 2,004 citations

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

2003 • 1,925 citations

Neuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes

2002 • 1,795 citations

Comorbidity of attention deficit hyperactivity disorder with conduct, depressive, anxiety, and other disorders

1991 • 1,739 citations

Developmental Trajectories of Brain Volume Abnormalities in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder

2002 • 1,610 citations

Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of Novelty Seeking

1996 • 1,498 citations

Faster sequential genetic linkage computations.

1993 • 1,378 citations

The Wender Utah Rating Scale: an aid in the retrospective diagnosis of childhood attention deficit hyperactivity disorder [published erratum appears in Am J Psychiatry 1993 Aug;150(8):1280]

1993 • 1,365 citations

Population and familial association between the D4 dopamine receptor gene and measures of Novelty Seeking

1996 • 1,207 citations

Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics.

1996 • 1,201 citations

Attention-Deficit Hyperactivity Disorder: A Category or a Continuum? Genetic Analysis of a Large-Scale Twin Study

1997 • 973 citations

Handbook of Human Genetic Linkage.

1996 • 878 citations

Psychopharmacology: The Fourth Generation of Progress

1995 • 842 citations

Diagnostic Interview for Children and Adolescents (DICA)

2000 • 821 citations

Cross-cultural Feasibility, Reliability and Sources of Variance of the Composite International Diagnostic Interview (CIDI)

1991 • 816 citations

Further Evidence for Family-Genetic Risk Factors in Attention Deficit Hyperactivity Disorder

1992 • 772 citations

Meta-Analysis of the Association Between the 7-Repeat Allele of the Dopamine D₄ Receptor Gene and Attention Deficit Hyperactivity Disorder

2001 • 754 citations

Dopamine D4 receptor gene polymorphism is associated with attention deficit hyperactivity disorder.

1996 • 684 citations

A hypervariable segment in the human dopamine receptor D₄ (DRD4) gene

1993 • 536 citations

A Test for Linkage and Association in General Pedigrees: The Pedigree Disequilibrium Test

2000 • 532 citations

ADHD Is Associated With Early Initiation of Cigarette Smoking in Children and Adolescents

1997 • 515 citations

Wisconsin card sorting test performance as a measure of frontal lobe damage

1991 • 506 citations

The E280A presenilin 1 Alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology

1996 • 478 citations

Dopamine genes and ADHD

2000 • 454 citations

The world-wide distribution of allele frequencies at the human dopamine D4 receptor locus

1996 • 432 citations

A family study of the hyperactive child syndrome.

1971 • 409 citations

Linkage disequilibrium in growing and stable populations.

1994 • 360 citations

Behavior Assessment System for Children (BASC)

1999 • 322 citations

A Genomewide Scan for Loci Involved in Attention-Deficit/Hyperactivity Disorder

2002 • 299 citations

Strong Amerind/White Sex Bias and a Possible Sephardic Contribution among the Founders of a Population in Northwest Colombia

2000 • 296 citations

Statistical Methods in Genetic Epidemiology

2004 • 286 citations

Attention deficit/hyperactivity disorder children with a 7-repeat allele of the dopamine receptor D4 gene have extreme behavior but normal performance on critical neuropsychological tests of attention

2000 • 272 citations

Family-Based Tests of Association in the Presence of Linkage

2000 • 271 citations

Genetics of population isolates

2002 • 262 citations

Clinical features of early-onset Alzheimer disease in a large kindred with an E280A presenilin-1 mutation

1997 • 254 citations

Evidence of Familial Association Between Attention Deficit Disorder and Major Affective Disorders

1991 • 233 citations

Dopamine system genes and attention deficit hyperactivity disorder: a meta-analysis

2002 • 229 citations

Psychosocial and Clinical Correlates of ADHD in a Community Sample of School-Age Children

1999 • 225 citations

The Genetic Dissection of Complex Traits in a Founder Population

2001 • 197 citations

Evidence for linkage of a tandem duplication polymorphism upstream of the dopamine D4 receptor gene (DRD4) with attention deficit hyperactivity disorder (ADHD)

2000 • 190 citations

Familial association between attention deficit disorder and anxiety disorders

1991 • 187 citations

Prevalence of attention-deficit/hyperactivity disorder symptoms in 4- to 17-year-old children in the general population.

1999 • 186 citations

Attention deficit disorder in reading-disabled twins: Evidence for a genetic etiology

1992 • 180 citations

Lack of an association between a dopamine-4 receptor polymorphism and attention-deficit/hyperactivity disorder: genetic and brain morphometric analyses

1998 • 170 citations

Family-Based Tests of Association and Linkage That Use Unaffected Sibs, Covariates, and Interactions

2000 • 154 citations

Hyperactivity and Spelling Disability: Testing for Shared Genetic Aetiology

1993 • 153 citations

Behavior Assessment System for Children (BASC)

2010 • 150 citations

Power and Design Considerations for a General Class of Family-Based Association Tests: Quantitative Traits

2002 • 142 citations

Further Evidence for Family-Genetic Risk Factors in Attention Deficit Hyperactivity Disorder

2001 • 139 citations

Examining for association between candidate gene polymorphisms in the dopamine pathway and attention‐deficit hyperactivity disorder: A family‐based study

2001 • 132 citations

Genotype‐based association test for general pedigrees: The genotype‐PDT

2003 • 123 citations

The short DRD4 repeats confer risk to attention deficit hyperactivity disorder in a family-based design and impair performance on a continuous performance test (TOVA)

2002 • 121 citations

Power Calculations for a General Class of Family-Based Association Tests: Dichotomous Traits

2002 • 119 citations

Associations Between ADHD and Psychoactive Substance use Disorders:Findings from a Longitudinal Study of High-Risk Siblings of ADHD Children

1997 • 118 citations

Advances in Protaglandin, Thromboxane, and Leukotriene Research, Ninth International Conference on Prostaglandins and Related Compounds

1996 • 112 citations

On a general class of conditional tests for family‐based association studies in genetics: the asymptotic distribution, the conditional power, and optimality considerations

2002 • 109 citations

New versions of World Health Organization instruments for the assessment of mental disorders

1994 • 107 citations

Tandem duplication polymorphism upstream of the dopamine D4 receptor gene (DRD4)

1999 • 104 citations

Further Evidence of an Association Between Attention-Deficit/Hyperactivity Disorder and Cigarette Smoking:Findings from a High-Risk Sample of Siblings

1997 • 98 citations

No association of the dopamine DRD4 receptor (DRD4) gene polymorphism with attention deficit hyperactivity disorder (ADHD) in the Irish population

2000 • 97 citations

E280A PS-1 mutation causes Alzheimer's disease but age of onset is not modified by ApoE alleles

1997 • 90 citations

A haplotype relative risk study of the dopamine D4 receptor (DRD4) exon III repeat polymorphism and attention deficit hyperactivity disorder (ADHD)

2000 • 90 citations

Confirmación de la alta prevalencia del trastorno por déficit de atención en una comunidad colombiana

2001 • 84 citations

Failure to replicate an excess of the long dopamine D4 exon III repeat polymorphism in ADHD in a family-based study

2000 • 83 citations

No association of the dopamine DRD4 receptor (DRD4) gene polymorphism with attention deficit hyperactivity disorder (ADHD) in the Irish population

2000 • 81 citations

Attention deficit hyperactivity disorder (ADHD) and the dopamine D4 receptor gene: evidence of association but no linkage in a UK sample

2001 • 77 citations

Probability of Gene Identity by Descent: Computation and Applications

1994 • 65 citations

Genes and attention deficit hyperactivity disorder

2001 • 63 citations

C455R notch3 mutation in a Colombian CADASIL kindred with early onset of stroke

2002 • 63 citations

Linkage studies between attention‐deficit hyperactivity disorder and the monoamine oxidase genes

2001 • 62 citations

Polymorphisms and phyletic relationships of the Paisa community from Antioquia (Colombia).

1996 • 60 citations

Preferential transmission of interleukin-1 receptor antagonist alleles in attention deficit hyperactivity disorder

2002 • 59 citations

A novel Cys212Tyr founder mutation in parkin and allelic heterogeneity of juvenile Parkinsonism in a population from North West Colombia

2001 • 57 citations

QTL association analysis of the DRD4 exon 3 VNTR polymorphism in a population sample of children screened with a parent rating scale for ADHD symptoms

2001 • 53 citations

Attention Deficit Hyperactivity Disorder and the Gene for Dopamine Beta-Hydroxylase

2002 • 53 citations

Associations Between ADHD and Psychoactive Substance Use Disorders

1997 • 52 citations

Dopa decarboxylase gene polymorphisms and attention deficit hyperactivity disorder (ADHD): no evidence for association in the Irish population

2001 • 40 citations

Further Evidence of an Association Between Attention‐Deficit/Hyperactivity Disorder and Cigarette Smoking

1997 • 37 citations

Segregation analysis of attention deficit hyperactivity disorder

1999 • 35 citations

Attention‐deficit/hyperactivity disorder (ADHD): feasibility of linkage analysis in a genetic isolate using extended and multigenerational pedigrees

2002 • 34 citations

Introduction and overview

2000 • 32 citations

No association between CHRNA7 microsatellite markers and attention‐deficit hyperactivity disorder

2001 • 29 citations

Familial Risk Analysis of the Association Between Attention-Deficit/Hyperactivity Disorder and Psychoactive Substance Use Disorders

1998 • 28 citations

Idiopathic epilepsy with generalized tonic clonic seizures in Antioquia, Colombia: is the joint Amerindian and Negroid racial admixture the cause of its high prevalence?

1996 • 25 citations

Mutation screening of the dopamine D2 receptor gene in attention‐deficit hyperactivity disorder subtypes: Preliminary report of a research strategy

2002 • 22 citations

Evolution of exon 1 of the dopamine D4 receptor (DRD4) gene in primates

2000 • 19 citations

The dopamine D4 receptor.

1996 • 18 citations

Uso de una escala multidimensional para padres de niños de 6 a 11 años en el diagnóstico de deficiencia atencional con hiperactividad

1999 • 15 citations

Behavioral effects of D-Ala2-β-endorphin in squirrel monkeys

1978 • 14 citations

Demencia vascular hereditaria tipo CADASIL en Colombia. III. Análisis de ligamiento a Notch3

2001 • 4 citations

[Determination of psychometric properties of the Geriatric Depression Scale (Yesavage & Brink, 1983) in a sample of aged Puerto Ricans].

2000 • 2 citations