Increased matrix metalloproteinases in the aqueous humor of patients and experimental animals with uveitis

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates

1980 • 1,991 citations

Metalloproteinases and their inhibitors in matrix remodeling

1990 • 1,627 citations

SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human Macrophages

1989 • 1,122 citations

Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage.

1989 • 604 citations

Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development.

1990 • 459 citations

Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP)

1991 • 454 citations

ACUTE ANTERIOR UVEITIS AND HL-A 27

1973 • 416 citations

Discoordinate expression of stromelysin, collagenase, and tissue inhibitor of metalloproteinases-1 in rheumatoid human synovial fibroblasts. Synergistic effects of interleukin-1 and tumor necrosis factor-alpha on stromelysin expression.

1990 • 408 citations

Acute anterior uveitis and HLA-B27

1991 • 357 citations

Differential roles for two gelatinolytic enzymes of the matrix metalloproteinase family in the remodelling cornea

1991 • 257 citations

Expression of a metalloproteinase that degrades native type V collagen and denatured collagens by cultured human alveolar macrophages.

1987 • 235 citations

Characterization of gelatinase from pig polymorphonuclear leucocytes. A metalloproteinase resembling tumour type IV collagenase

1989 • 233 citations

Human skin fibroblast collagenase inhibitor. Comparative studies in human connective tissues, serum, and amniotic fluid.

1983 • 231 citations

The role of cytokines in the pathogenesis of inflammatory eye disease

1992 • 218 citations

Cloning of the cDNA Encoding Human Tissue Inhibitor of Metalloproteinases-3 (TIMP-3) and Mapping of the TIMP3 Gene to Chromosome 22

1994 • 214 citations

Expression of collagenolytic/gelatinolytic metalloproteinases by normal cornea.

1990 • 200 citations

Expression of matrix metalloproteinases and inhibitor by human trabecular meshwork.

1991 • 181 citations

Direct contact between T lymphocytes and monocytes is a major pathway for induction of metalloproteinase expression.

1994 • 180 citations

[31] Quantification of matrix metalloproteinases in tissue samples

1995 • 171 citations

The purification of tissue inhibitor of metalloproteinases-2 from its 72 kDa progelatinase complex. Demonstration of the biochemical similarities of tissue inhibitor of metalloproteinases-2 and tissue inhibitor of metalloproteinases-1

1991 • 164 citations

Direct activation of human neutrophil procollagenase by recombinant stromelysin

1993 • 162 citations

Levels of circulating collagenase, stromelysin‐1, and tissue inhibitor of matrix metalloproteinases 1 in patients with rheumatoid arthritis: relationship to serum levels of antigenic keratan sulfate and systemic parameters of inflammation

1995 • 123 citations

Sequence specificity of human skin fibroblast collagenase. Evidence for the role of collagen structure in determining the collagenase cleavage site.

1987 • 120 citations

Tumor-promoting phorbol esters and cell proliferation stimulate secretion of basement membrane (type IV) collagen-degrading metalloproteinase by human fibroblasts.

1985 • 96 citations

Retinoids modulate endothelial cell production of matrix-degrading proteases and tissue inhibitors of metalloproteinases (TIMP).

1994 • 89 citations

UVEITIS: AETIOLOGY AND DISEASE ASSOCIATIONS IN AN AUSTRALIAN POPULATION

1986 • 89 citations

Production and regulation of gelatinase B by human T-cells

1993 • 80 citations

MMPs and proteinase inhibitors in the human aqueous humor.

1993 • 66 citations

Cytokines cause cultured retinal pigment epithelial cells to secrete metalloproteinases and to contract collagen gels.

1993 • 56 citations

Characterization of a human corneal metalloproteinase inhibitor (TIMP-1)

1993 • 32 citations

A latent collagenase in human aqueous humor.

1989 • 29 citations

Interleukin-1-beta changes the expression of metalloproteinases in the vitreous humor and induces membrane formation in eyes containing preexisting retinal holes.

1994 • 24 citations

Aqueous humor cytokine profile in patients with chronic uveitis

1995 • 14 citations

Stromelysin (matrix metalloproteinase-3) and tissue inhibitor of metalloproteinase (TIMP-1) mRNA expression in scleritis

1995 • 8 citations

Immunoelectron Microscopic Localization of Gelatinase A in Human Gastrointestinal and Skin Carcinomas: Difference between Cancer Cells and Fibroblasts

1995 • 7 citations

Polyamine and histopathological changes after unilateral endotoxin‐induced uveitis and its contralateral effects

1992 • 3 citations