Synthesis and Pharmacological Characterization of All Sixteen Stereoisomers of 2-(2‘-Carboxy-3‘-phenylcyclopropyl)glycine. Focus on (2S,1‘S,2‘S,3‘R)-2-(2‘-Carboxy-3‘-phenylcyclopropyl)glycine, a Novel and Selective Group II Metabotropic Glutamate Receptors Antagonist

On enantiomorph-polarity estimation

1983 • 10,286 citations

Molecular Diversity of Glutamate Receptors and Implications for Brain Function

1992 • 2,535 citations

Excitatory amino acid neurotoxicity and neurodegenerative disease

1990 • 1,781 citations

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a Neuroprotectant for Cerebral Ischemia

1990 • 1,125 citations

Signal transduction, pharmacological properties, and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4

1993 • 585 citations

A molecular switch activated by metabotropic glutamate receptors regulates induction of long-term potentiation

1994 • 405 citations

Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes

1994 • 323 citations

Phenylglycine derivatives as antagonists of metabotropic glutamate receptors

1994 • 303 citations

A novel metabotropic glutamate receptor agonist: marked depression of monosynaptic excitation in the newborn rat isolated spinal cord

1993 • 197 citations

1-Aminoindan-1,5-dicarboxylic Acid: A Novel Antagonist at Phospholipase C-Linked Metabotropic Glutamate Receptors

1995 • 173 citations

On the use of least-squares restraints for origin fixing in polar space groups

1988 • 148 citations

Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system

1993 • 144 citations

Actions of phenylglycine analogs at subtypes of the metabotropic glutamate receptor family

1994 • 139 citations

Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death

1994 • 122 citations

Metabotropic Glutamate Receptor Activation Produces Extrapyramidal Motor System Activation That Is Mediated by Striatal Dopamine

1992 • 117 citations

Syntheses and Conformational Analyses of Glutamate Analogs: 2-(2-Carboxy-3-substituted-cyclopropyl)glycines as Useful Probes for Excitatory Amino Acid Receptors

1996 • 111 citations

A pharmacological characterization of the mGluR1α subtype of the metabotropic glutamate receptor expressed in a cloned baby hamster kidney cell line

1993 • 96 citations

Inhibition of exocytosis in bovine adrenal medullary cells by botulinum toxin type D

1985 • 96 citations

A potent metabotropic glutamate receptor agonist: electrophysiological actions of a conformationally restricted glutamate analogue in the rat spinal cord and Xenopus oocytes

1990 • 79 citations

(R,S)-α-Methyl-4-carboxyphenylglycine (MCPG) blocks spatial learning in rats and long-term potentiation in the dentate gyrus in vivo

1994 • 78 citations

Potent NMDA‐like actions and potentiation of glutamate responses by conformational variants of a glutamate analogue in the rat spinal cord

1989 • 77 citations

Synthesis of L-2-(2,3-dicarboxyclopropyl)glycines. Novel conformationally restricted glutamate analogues.

1993 • 76 citations

Trends in receptor research

1992 • 74 citations

Regional Heterogeneity of L‐Glutamate and L‐Aspartate High‐Affinity Uptake Systems in the Rat CNS

1991 • 69 citations

Characterization of the binding of <scp>dl</scp>‐[³H]‐2‐amino‐4‐phosphonobutyrate to <scp>l</scp>‐glutamate‐sensitive sites on rat brain synaptic membranes

1983 • 62 citations

Copper (II) and Nickel (II) N-(n-alkyl)salicylaldimine Chelates

1957 • 52 citations

A novel metabotropic glutamate receptor agonist: (2S, 1′S,2′R,3′R)-2-(2-carboxy-3-methoxymethylcyclopropyl)glycine (cis-MCG-I)

1994 • 34 citations

Novel agonists for metabotropic glutamate receptors: trans- and cis-2-(2-carboxy-3-methoxymethylcyclopropyl)glycine (trans- and cis-MCG-I)

1995 • 28 citations

Definition of a pharmacophore for the metabotropic glutamate receptors negatively linked to adenylyl cyclase

1993 • 18 citations

Inside-outside stereoisomerism. 4. An unusual rearrangement of the trans-bicyclo[5.3.1]undecan-11-yl radical

1989 • 16 citations