Impaired Osteoclast Formation in Bone Marrow Cultures of Fgf2 Null Mice in Response to Parathyroid Hormone

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation

1998 • 5,369 citations

Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density

1997 • 5,058 citations

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

1998 • 4,184 citations

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

1997 • 2,257 citations

Modulation of Osteoclast Differentiation and Function by the New Members of the Tumor Necrosis Factor Receptor and Ligand Families

1999 • 2,238 citations

Therapeutic Approaches to Bone Diseases

2000 • 1,732 citations

Principles of Bone Biology

1997 • 1,367 citations

TRANCE Is a Novel Ligand of the Tumor Necrosis Factor Receptor Family That Activates c-Jun N-terminal Kinase in T Cells

1997 • 1,054 citations

Modulation of Osteoclast Differentiation

1992 • 1,014 citations

Growth factors in bone matrix. Isolation of multiple types by affinity chromatography on heparin-Sepharose.

1986 • 870 citations

TRANCE (Tumor Necrosis Factor [TNF]-related Activation-induced Cytokine), a New TNF Family Member Predominantly Expressed in T cells, Is a Dendritic Cell–specific Survival Factor

1997 • 869 citations

Osteoclast-Like Cell Formation and its Regulation by Osteotropic Hormones in Mouse Bone Marrow Cultures*

1988 • 745 citations

Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2

1998 • 593 citations

Role of receptor activator of nuclear factor-κB ligand and osteoprotegerin in bone cell biology

2001 • 574 citations

IL-6 stimulates osteoclast-like multinucleated cell formation in long term human marrow cultures by inducing IL-1 release.

1990 • 493 citations

Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation

2000 • 467 citations

Interleukin-1 and tumor necrosis factor stimulate the formation of human osteoclastlike cells in vitro

1989 • 467 citations

Parathyroid Hormone Stimulates TRANCE and Inhibits Osteoprotegerin Messenger Ribonucleic Acid Expression in Murine Bone Marrow Cultures: Correlation with Osteoclast-Like Cell Formation*

1999 • 443 citations

Impaired cerebral cortex development and blood pressure regulation in FGF-2-deficient mice

1998 • 437 citations

Interleukin-11: a new cytokine critical for osteoclast development.

1994 • 408 citations

Immunological Characterization of Circulating Osteoprotegerin/Osteoclastogenesis Inhibitory Factor: Increased Serum Concentrations in Postmenopausal Women with Osteoporosis

1999 • 378 citations

Fibroblast growth factor 2 control of vascular tone

1998 • 376 citations

Target cells in bone for parathormone and calcitonin are different: enrichment for each cell type by sequential digestion of mouse calvaria and selective adhesion to polymeric surfaces.

1975 • 357 citations

Cultured Bovine Bone Cells Synthesize Basic Fibroblast Growth Factor and Store It in Their Extracellular Matrix

1989 • 297 citations

Resorption of dentine by isolated osteoclasts in vitro

1984 • 296 citations

1,25-Dihydroxyvitamin D3 causes formation of multinucleated cells with several osteoclast characteristics in cultures of primate marrow.

1985 • 280 citations

Regulation of Bovine Bone Cell Proliferation by Fibroblast Growth Factor and Transforming Growth Factorβ

1988 • 264 citations

"Pure" Human Hematopoietic Progenitors: Permissive Action of Basic Fibroblast Growth Factor

1990 • 248 citations

Effects of human recombinant CSF-GM and highly purified CSF-1 on the formation of multinucleated cells with osteoclast characteristics in long-term bone marrow cultures

1986 • 215 citations

Basic fibroblast growth factor expression in human bone marrow and peripheral blood cells

1993 • 187 citations

Formation of Multinucleated Cells that Respond to Osteotropic Hormones in Long Term Human Bone Marrow Cultures*

1987 • 164 citations

Transcriptional induction of prostaglandin G/H synthase-2 by basic fibroblast growth factor.

1995 • 144 citations

Basic Fibroblast Growth Factor Induces Osteoclast Formation in Murine Bone Marrow Cultures

1998 • 132 citations

Expression and regulation of basic fibroblast growth factor mRNA levels in mouse osteoblastic MC3T3-E1 cells.

1994 • 126 citations

Basic fibroblast growth factor stimulates myelopoiesis in long-term human bone marrow cultures

1991 • 112 citations

Parathyroid Hormone Regulates the Expression of Fibroblast Growth Factor-2 mRNA and Fibroblast Growth Factor Receptor mRNA in Osteoblastic Cells

1999 • 106 citations

Fibroblast Growth Factor (FGF)-2 Directly Stimulates Mature Osteoclast Function through Activation of FGF Receptor 1 and p42/p44 MAP Kinase

2000 • 102 citations

Comparison of bone formation responses to parathyroid hormone(1-34), (1-31), and (2-34) in mice

2000 • 100 citations

Bone and Cytokines: Beyond IL-1, IL-6 and TNF-α

1999 • 88 citations

Long-Term Culture of Human Bone Marrow Stromal Cells in the Presence of Basic Fibroblast Growth Factor

1990 • 83 citations

Effects of interleukin 3 and of granulocyte‐macrophage and macrophage colony stimulating factors on osteoclast differentiation from mouse hemopoietic tissue

1990 • 83 citations

Direct and Indirect Actions of Fibroblast Growth Factor 2 on Osteoclastic Bone Resorption in Cultures

2000 • 82 citations

Reduced Expression of Interleukin-11 in Bone Marrow Stromal Cells of Senescence-Accelerated Mice (SAMP6): Relationship to Osteopenia with Enhanced Adipogenesis

1998 • 79 citations

Stem cell factor and basic fibroblast growth factor are synergistic in augmenting committed myeloid progenitor cell growth

1994 • 72 citations

Osteoporosis and osteopenia

1990 • 72 citations

Bone resorption by isolated human osteoclasts in vitro: Effects of calcitonin

1989 • 71 citations

Establishment and Characterization of an Immortal Macrophage-like Cell Line Inducible to Differentiate to Osteoclasts

1998 • 68 citations

Basic Fibroblast Growth Factor Induces Osteoclast Formation by Reciprocally Regulating the Production of Osteoclast Differentiation Factor and Osteoclastogenesis Inhibitory Factor in Mouse Osteoblastic Cells

1999 • 65 citations

Development and characterization of a human marrow stromal cell line that enhances osteoclast-like cell formation.

1995 • 37 citations

New reagent for colorimetric assay of calcium in serum

1993 • 22 citations

Application of Bone Marrow Cultures to the Study of Osteoclast Formation and Osteoclast Precursors in Man

1995 • 14 citations

Protein Kinase C Is a Mediator of the Synthesis and Secretion of Osteoprotegerin in Osteoblast-like Cells

2002 • 12 citations

Parathyroid Hormone

2001 • 5 citations