Absence of seven human herpesviruses, including HHV-6, by polymerase chain reaction in CSF and blood from patients with multiple sclerosis and optic neuritis

Rating neurologic impairment in multiple sclerosis

1983 • 14,011 citations

New diagnostic criteria for multiple sclerosis: Guidelines for research protocols

1983 • 7,404 citations

IDENTIFICATION OF HUMAN HERPESVIRUS-6 AS A CAUSAL AGENT FOR EXANTHEM SUBITUM

1988 • 1,448 citations

Isolation of a New Virus, HBLV, in Patients with Lymphoproliferative Disorders

1986 • 1,442 citations

PROBLEMS OF EXPERIMENTAL TRIALS OF THERAPY IN MULTIPLE SCLEROSIS: REPORT BY THE PANEL ON THE EVALUATION OF EXPERIMENTAL TRIALS OF THERAPY IN MULTIPLE SCLEROSIS

1965 • 1,402 citations

Plaque-associated expression of human herpesvirus 6 in multiple sclerosis.

1995 • 611 citations

Rapid diagnosis of herpes simplex encephalitis by nested polymerase chain reaction assay of cerebrospinal fluid

1991 • 549 citations

Epidemiologic evidence for multiple sclerosis as an infection

1993 • 467 citations

Tumor necrosis factor‐α messenger RNA expression in patients with relapsing‐remitting multiple sclerosis is associated with disease activity

1995 • 336 citations

Epstein-Barr virus DNA in cerebrospinal fluid from patients with AIDS-related primary lymphoma of the central nervous system

1993 • 322 citations

Encephalitis in immunocompetent patients due to herpes simplex virus type 1 or 2 as determined by type‐specific polymerase chain reaction and antibody assays of cerebrospinal fluid

1993 • 247 citations

Neuroinvasion And Persistence Of Human Herpesvirus 6 In Children

1994 • 228 citations

Polymerase chain reaction on cerebrospinal fluid for diagnosis of virus-associated opportunistic diseases of the central nervous system in HIV-infected patients

1996 • 207 citations

Improved detection of oligoclonal IgG in cerebrospinal fluid by isoelectric focusing in agarose, double-antibody peroxidase labeling, and avidin-biotin amplification.

1984 • 199 citations

Lymphotropic herpesviruses in allogeneic bone marrow transplantation

1996 • 190 citations

Principles of albumin and IgG analyses in neurological disorders. II. Relation of the concentration of the proteins in serum and cerebrospinal fluid

1977 • 181 citations

Comparison of Antibodies Against Different Viruses in Cerebrospinal Fluid and Serum Samples from Patients with Multiple Sclerosis

1974 • 173 citations

Principles of albumin and IgG analyses in neurological disorders. II. Relation of the concentration of the proteins in serum and cerebrospinal fluid

1977 • 169 citations

The virology of demyelinating diseases

1994 • 149 citations

The diagnostic significance of antibody specificity indices in multiple sclerosis and herpes virus induced diseases of the nervous system

1992 • 140 citations

Cytomegalovirus Infection of the Central Nervous System in Patients with AIDS: Diagnosis by DNA Amplification from Cerebrospinal Fluid

1992 • 132 citations

A potential role for human herpesvirus type 6 in nervous system disease

1994 • 124 citations

Increased prevalence and titer of Epstein‐Barr virus antibodies in patients with multiple sclerosis

1985 • 120 citations

Acyclovir treatment of relapsing-remitting multiple sclerosis

1996 • 120 citations

Human herpesvirus 6 and multiple sclerosis: survey of anti-HHV-6 antibodies by immunofluorescence analysis and of viral sequences by polymerase chain reaction.

1993 • 112 citations

Active human herpesvirus (HHV-6) infection of the central nervous system in patients with AIDS.

1995 • 88 citations

Human herpesvirus 6 polymerase chain reaction findings in human immunodeficiency virus associated neurological disease and multiple sclerosis

1995 • 78 citations

Diagnosis of Epstein-Barr virus-induced central nervous system infections by DNA amplification from cerebrospinal fluid

1994 • 68 citations

Viral Etiology of Acute Childhood Encephalitis in Beijing Diagnosed by Analysis of Single Samples

1996 • 56 citations

Isolation of herpes simplex virus type 1 during first attack of multiple sclerosis

1989 • 52 citations

Polymerase chain reaction for diagnosis of varicella zoster virus central nervous system infections without skin manifestations.

1996 • 51 citations

Cytomegalovirus infection of the CNS in non-compromised patients

2009 • 47 citations

A Putative New Retrovirus Associated with Multiple Sclerosis and the Possible Involvement of Epstein‐Barr Virus in This Disease^a

1994 • 41 citations

Varicella zoster virus and multiple sclerosis in a hutterite population

1995 • 38 citations

Total, anti-viral, and anti-myelin IgG subclass reactivity in inflammatory diseases of the central nervous system

1989 • 33 citations

Herpes-simplex-related antigen in human demyelinative disease and encephalitis

1988 • 25 citations

Virus-induced demyelination in man: models for multiple sclerosis.

1992 • 16 citations

The clinical and paraclinical profile of optic neuritis: A prospective study

1995 • 15 citations