Evidence for major alterations in the thymocyte subpopulations in murine models of autoimmune diseases

T cell tolerance by clonal elimination in the thymus

1987 • 2,248 citations

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

1988 • 1,711 citations

Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

1988 • 671 citations

A monoclonal antibody discriminating between subsets of T and B cells.

1981 • 565 citations

Etiopathogenesis of Murine SLE¹

1981 • 517 citations

T Cell Development in the Adult Murine Thymus: Changes in the Expression of the Surface Antigens Ly2, L3T4 and B2A2 during Development from Early Precursor Cells to Emigrants

1984 • 344 citations

Effects of thymectomy or androgen administration upon the autoimmune disease of MRL/Mp-lpr/lpr mice.

1980 • 331 citations

Early T lymphocytes. Differentiation in vivo of adult intrathymic precursor cells.

1985 • 305 citations

Abnormalities induced by the mutant gene Ipr: expansion of a unique lymphocyte subset.

1982 • 295 citations

Precursors of T cell growth factor producing cells in the thymus: ontogeny, frequency, and quantitative recovery in a subpopulation of phenotypically mature thymocytes defined by monoclonal antibody GK-1.5.

1983 • 237 citations

Phenotypic, functional, and molecular genetic comparisons of the abnormal lymphoid cells of C3H-lpr/lpr and C3H-gld/gld mice.

1986 • 224 citations

Expression and functional significance of the J11d marker on mouse thymocytes.

1987 • 218 citations

Developmental Status and Reconstitution Potential of Subpopulations of Murine Thymocytes

1988 • 211 citations

A single stem cell can recolonize an embryonic thymus, producing phenotypically distinct T-cell populations

1985 • 199 citations

Intrathymic deletion of self-reactive cells prevented by neonatal anti-CD4 antibody treatment

1988 • 197 citations

Cell Surface Antigen Expression on Thymocytes: Development and Phenotypic Differentiation of Intrathymic Subsets

1984 • 179 citations

Differentiation potential of subsets of CD4−8− thymocytes

1987 • 169 citations

Presence of anti-Sm reactivity in autoimmune mouse strains

1978 • 168 citations

Deletion of potentially self-reactive T cell receptor specificities in L3T4-, Lyt-2- T cells of lpr mice.

1988 • 142 citations

Phenotypic properties, interleukin 2 production, and developmental origin of a "mature" subpopulation of Lyt-2- L3T4- mouse thymocytes.

1987 • 76 citations

CD4+ murine T cells develop from CD8+ precursors in vivo

1987 • 71 citations

T cell lineages in the thymus of lpr/lpr mice. Evidence for parallel pathways of normal and abnormal T cell development.

1987 • 66 citations

Effects of Neonatal Thymectomy and Splenectomy on Survival and Regulation of Autoantibody Formation in NZB/NZW F1 Mice

1977 • 63 citations

Characterization and differentiation of CD4-, CD8- thymocytes sorted with the Ly-24 marker.

1988 • 47 citations

Consequences of neonatal thymectomy in New Zealand black mice.

1967 • 39 citations

Evidence for thymic regulation of autoimmunity in BXSB mice: acceleration of disease by neonatal thymectomy.

1983 • 37 citations

Normal Lyt-1+2- T cells have the unique capacity to respond to syngeneic autoreactive T cells. Demonstration of a T cell network.

1985 • 33 citations

Expression of the J11d marker on peripheral T lymphocytes of MRL-lpr/lpr mice.

1988 • 30 citations

Characterization of an endogenous Lyt 2+ T-suppressor-cell population regulating autoreactive T cells in vitro and in vivo

1988 • 21 citations

A single gene model for massive lymphoproliferation with autoimmunity in new mouse strain mrl. Abstr.

1977 • 16 citations

Chemotherapy of mice bearing syngeneic tumors with 1,3-bis (2-chloroethyl)-1-nitrosourea is effective only in normal, but not in irradiated or nude, mice: Role of L3T4+ (CD4+) and Lyt-2+ (CD8+) T cells

1988 • 15 citations

Genetic, Viral and Immunologic Aspects of Autoimmune Disease in NZB Mice

1978 • 12 citations