Failure of clonal deletion in neonatally thymectomized mice: tolerance is preserved through clonal anergy.

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo.

1987 • 1,166 citations

Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition

1981 • 1,048 citations

Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen

1989 • 1,010 citations

Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens.

1980 • 850 citations

Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor.

1985 • 676 citations

The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens

1988 • 491 citations

The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype.

1984 • 389 citations

Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis.

1982 • 321 citations

Deletion of self-reactive thymocytes occurs at a CD4+8+ precursor stage

1988 • 265 citations

Study on cellular events in postthymectomy autoimmune oophoritis in mice. I. Requirement of Lyt-1 effector cells for oocytes damage after adoptive transfer.

1982 • 217 citations

Intrathymic deletion of self-reactive cells prevented by neonatal anti-CD4 antibody treatment

1988 • 197 citations

Self tolerance and localized autoimmunity. Mouse models of autoimmune disease that suggest tissue-specific suppressor T cells are involved in self tolerance.

1987 • 166 citations

Phenotypic differences between αβ versus β T-cell receptor transgenic mice undergoing negative selection

1989 • 147 citations

Positive selection determines T cell receptor V beta 14 gene usage by CD8+ T cells.

1989 • 146 citations

The T cell receptor Vβ6 domain imparts reactivity to the Mls-1a antigen

1989 • 114 citations

Postnatal disappearance of self-reactive (V beta 6+) cells from the thymus of Mlsa mice. Implications for T cell development and autoimmunity.

1989 • 108 citations

Expression of a murine polyclonal T cell receptor marker correlates with the use of specific members of the V beta 8 gene segment subfamily.

1987 • 73 citations

Capacity of unprimed CD4+ and CD8+ T cells expressing V beta 11 receptors to respond to I-E alloantigens in vivo.

1989 • 53 citations

Selective activation of Lyt 2+ precursor T cells by ligation of the antigen receptor

1985 • 51 citations

Circulating cellfree Fc gamma 2b/gamma 1 receptor in normal mouse serum: its detection and specificity.

1984 • 50 citations

Response of mature unprimed CD8+ T cells to Mlsa determinants.

1990 • 47 citations

CD8+ T cells respond clonally to Mls-1a-encoded determinants.

1990 • 41 citations

Both TCR/MHC and Accessory Molecule/MHC Interactions Are Required for Positive and Negative Selection of Mature T Cells in the Thymus

1989 • 11 citations