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Role of isosafrole as complexing agent and inducer of P-450LM4 in rabbit liver microsomes

Data up to Jan 2025

Published1982
Citations13
References19

Total Citations Per Year

Abstract

References (19)

An improved assay of 7-ethoxycoumarin O-deethylase activity: induction of hepatic enzyme activity in C57BL/6J and DBA/2J mice by phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin.

1978 • 618 citations

Properties of electrophoretically homogeneous phenobarbital-inducible and beta-naphthoflavone-inducible forms of liver microsomal cytochrome P-450

1976 • 536 citations

Preparation and Properties of Partially Purified Cytochrome P-450 and Reduced Nicotinamide Adenine Dinucleotide Phosphate-Cytochrome P-450 Reductase from Rabbit Liver Microsomes

1974 • 518 citations

Microsomes, Drug Oxidations and Chemical Carcinogenesis

1980 • 498 citations

Mixed-function oxidase involvement in the biochemistry of insecticide synergists

1970 • 377 citations

Hepatic microsomal cytochrome P-450 from rats treated with isosafrole. Purification and characterization of four enzymic forms.

1980 • 286 citations

Properties of NADPH-cytochrome P-450 reductase purified from rabbit liver microsomes

1979 • 181 citations

[10] Two forms of liver microsomal cytochrome P-450, P-450lm2 and P-450lm4 (rabbit liver)

1978 • 151 citations

The Enzymic Formation of a Methylenedioxyphenyl Derivative Exhibiting an Isocyanide-like Spectrum with Reduced Cytochrome P-450 in Hepatic Microsomes

1971 • 134 citations

A cytochrome P-450-piperonyl butoxide spectrum similar to that produced by ethyl isocyanide

1971 • 108 citations

Biochemistry, Biophysics and Regulation of Cytochrome P-450

1981 • 88 citations

Isolation, purification, and properties of a unique form of cytochrome P-450 in microsomes of isosafrole-treated rats.

1981 • 85 citations

Studies on the interaction of safrole with rat hepatic microsomes

1975 • 82 citations

Properties of housefly microsomal cytochromes in relation to sex, strain, substrate specificity, and apparent inhibition and induction by synergist and insecticide chemicals

1970 • 59 citations

Generation of carbon monoxide during the microsomal metabolism of methylenedioxyphenyl compounds

1980 • 48 citations

Insecticide synergist interactions with cytochrome P-450 in mouse liver microsomes

1970 • 48 citations

Induction of a new hepatic microsomal haemoprotein by safrole and isosafrole

1971 • 42 citations

Substrate-elicited dissociation of a complex of cytochrome P-450 with a methylenedioxyphenyl metabolite

1976 • 23 citations

Interaction of safrole and isosafrole with hepatic microsomal haemoproteins

1972 • 21 citations

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Role of isosafrole as complexing agent and inducer of P-450LM4 in rabbit liver microsomes (1982) – Biochemical and Biophysical Research Communications | Metascience Observatory Explorer