Is fatal pancreatitis a consequence of excessive leukocyte stimulation? The role of tumor necrosis factor α

Shock and Tissue Injury Induced by Recombinant Human Cachectin

1986 • 2,587 citations

Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

1987 • 2,492 citations

Detection of Circulating Tumor Necrosis Factor after Endotoxin Administration

1988 • 1,711 citations

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.

1986 • 1,501 citations

Neutrophil activation on biological surfaces. Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes.

1987 • 823 citations

Peptide Regulatory Factors

1989 • 498 citations

Tumor necrosis factor and interleukin-1 serum levels during severe sepsis in humans

1989 • 485 citations

Plasma tumor necrosis factor and mortality in critically ill septic patients

1989 • 324 citations

Fatal pancreatitis, a consequence of excessive leukocyte stimulation?

1988 • 212 citations

Pharmacological methods in the control of inflammation

1989 • 191 citations

Released granulocytic elastase: an indicator of pathobiochemical alterations in septicemia after abdominal surgery.

1985 • 176 citations

Granulocyte elastase in assessment of severity of acute pancreatitis

1990 • 156 citations

Neutral Proteases of Human Granulocytes III. Interaction between Human Granulocyte Elastase and Plasma Protease Inhibitors

1974 • 153 citations

Circulating human leucocyte elastase in patients with inflammatory bowel disease.

1985 • 76 citations

Inhibition of Neutrophil Elastase by Alpha-1-Proteinase Inhibitor Oxidized by Activated Neutrophils

1989 • 52 citations

Elastase-α1-proteinase inhibitor: An early indicator of septicemia and bacterial meningitis in children

1987 • 48 citations

Recombinant human tumor necrosis factor causes long-lasting and prostaglandin-mediated fever, with little tolerance, in rabbits.

1988 • 38 citations

Free radicals inactivate human neutrophil elastase and its inhibitors with comparable efficiency

1989 • 33 citations

Measurement of plasma concentrations of polymorphonuclear elastase-alpha 1 proteinase inhibitor (elastase-alpha 1 antitrypsin) in patients with rheumatoid arthritis: interference by rheumatoid factor.

1990 • 18 citations

Endotoxaemia in Patients with Crohn’s Disease: A Longitudinal Study of Elastase/α1-Proteinase Inhibitor and Limulus-Amoebocyte-Lysate Reactivity

1988 • 7 citations

Deleted Work

1955 • 0 citations