Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses

Epstein-Barr Virus

1986 • 2,255 citations

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2000 • 546 citations

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2003 • 388 citations

Recombinant gp350 Vaccine for Infectious Mononucleosis: A Phase 2, Randomized, Double‐Blind, Placebo‐Controlled Trial to Evaluate the Safety, Immunogenicity, and Efficacy of an Epstein‐Barr Virus Vaccine in Healthy Young Adults

2007 • 372 citations

Human Cd4+ T Lymphocytes Consistently Respond to the Latent Epstein-Barr Virus Nuclear Antigen Ebna1

2000 • 340 citations

Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses

2006 • 264 citations

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2007 • 238 citations

Disseminated and sustained HIV infection in CD34⁺cord blood cell-transplanted Rag2^−/−γ_c^−/−mice

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2002 • 215 citations

Human-Hemato-Lymphoid-System Mice: Opportunities and Challenges

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Epstein-Barr Nuclear Antigen 1-Specific CD4+ Th1 Cells Kill Burkitt’s Lymphoma Cells

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2003 • 165 citations

Endogenous Presentation of CD8+ T Cell Epitopes from Epstein-Barr Virus–encoded Nuclear Antigen 1

2004 • 156 citations

Phase I/II studies to evaluate safety and immunogenicity of a recombinant gp350 Epstein–Barr virus vaccine in healthy adults

2007 • 154 citations

CD8 T Cell Recognition of Endogenously Expressed Epstein-Barr Virus Nuclear Antigen 1

2004 • 152 citations

Evidence for the Presentation of Major Histocompatibility Complex Class I–restricted Epstein-Barr Virus Nuclear Antigen 1 Peptides to CD8+ T Lymphocytes

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2007 • 137 citations

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Down-regulation of class I HLA antigens and of the Epstein-Barr virus-encoded latent membrane protein in Burkitt lymphoma lines.

1987 • 133 citations

Human Immunodeficiency Virus Type 1 Pathobiology Studied in Humanized BALB/c-Rag2 ^−/− γ _c ^−/− Mice

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Compartmentalization and Transmission of Multiple Epstein-Barr Virus Strains in Asymptomatic Carriers

2003 • 130 citations

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2001 • 126 citations

A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells

2000 • 125 citations

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2003 • 124 citations

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Therapeutic LMP1 polyepitope vaccine for EBV-associated Hodgkin disease and nasopharyngeal carcinoma

2003 • 118 citations

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Multiple Epstein-Barr Virus Infections in Healthy Individuals

2003 • 111 citations

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2003 • 101 citations

Differentiation-dependent sensitivity of human B-cell-derived lines to major histocompatibility complex-restricted T-cell cytotoxicity.

1986 • 96 citations

Functional Inactivation of EBV-Specific T-Lymphocytes in Nasopharyngeal Carcinoma: Implications for Tumor Immunotherapy

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2001 • 87 citations

Loss of EBNA1-specific memory CD4+ and CD8+ T cells in HIV-infected patients progressing to AIDS-related non-Hodgkin lymphoma

2005 • 82 citations

Induction of Therapeutic T-Cell Responses to Subdominant Tumor-associated Viral Oncogene after Immunization with Replication-incompetent Polyepitope Adenovirus Vaccine

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2003 • 62 citations

Humanized NOD/LtSz‐scid IL2 Receptor Common Gamma Chain Knockout Mice in Diabetes Research

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Functional Reversion of Antigen-Specific CD8+ T Cells from Patients with Hodgkin Lymphoma following In Vitro Stimulation with Recombinant Polyepitope

2006 • 58 citations

Distinct memory CD4+ T-cell subsets mediate immune recognition of Epstein Barr virus nuclear antigen 1 in healthy virus carriers

2006 • 58 citations

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2007 • 54 citations

Pharmacologic effects of polyinosinic• polycytidylic acid in man

1977 • 48 citations

CD4 and CD8 T cell responses to tumour-associated Epstein–Barr virus antigens in nasopharyngeal carcinoma patients

2007 • 42 citations

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2005 • 26 citations

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2006 • 20 citations

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2007 • 17 citations