Buthionine sulfoximine-induced glutathione depletion

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Role of Superoxide Anion in the Autoxidation of Epinephrine and a Simple Assay for Superoxide Dismutase

1972 • 8,501 citations

Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent

1968 • 7,671 citations

Selenium: Biochemical Role as a Component of Glutathione Peroxidase

1973 • 7,616 citations

A SPECTROPHOTOMETRIC METHOD FOR MEASURING THE BREAKDOWN OF HYDROGEN PEROXIDE BY CATALASE

1952 • 6,430 citations

Hydroperoxide metabolism in mammalian organs.

1979 • 5,821 citations

GLUTATHIONE

1983 • 5,487 citations

Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver

1979 • 4,067 citations

THE COLORIMETRIC DETERMINATION OF LACTIC ACID IN BIOLOGICAL MATERIAL

1941 • 3,446 citations

Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung

1971 • 2,569 citations

[1] Selected methods for the determination of ascorbic acid in animal cells, tissues, and fluids

1979 • 1,853 citations

Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine).

1979 • 1,680 citations

BIOCHEMISTRY OF OXYGEN TOXICITY

1989 • 1,046 citations

Oxy-Radicals and Related Species: Their Formation, Lifetimes, and Reactions

1986 • 958 citations

Glutathione deficiency produced by inhibition of its synthesis, and its reversal; Applications in research and therapy

1991 • 906 citations

The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells.

1982 • 893 citations

[16] Vitamin E analysis methods for animal tissues

1984 • 857 citations

Metalloenzymes and myocardial infarction. II. Malic and lactic dehydrogenase activities and zinc concentrations in serum.

1956 • 669 citations

Inhibition of oxidation of methyl linoleate in solution by vitamin E and vitamin C.

1984 • 580 citations

Bleb Formation in Hepatocytes During Drug Metabolism Is Caused by Disturbances in Thiol and Calcium Ion Homeostasis

1982 • 553 citations

Effect of sulfhydryl reagents on peroxidation in microsomes

1967 • 435 citations

The detection of oxidation in liposome preparations

1970 • 408 citations

Regulation of intracellular calcium compartmentation: studies with isolated hepatocytes and t-butyl hydroperoxide.

1982 • 303 citations

Glutathione is required for intestinal function.

1990 • 279 citations

Glutathione depletion and susceptibility.

1984 • 249 citations

Glutathione export by human lymphoid cells: depletion of glutathione by inhibition of its synthesis decreases export and increases sensitivity to irradiation.

1981 • 230 citations

Regulation of reductive processes by glutathione

1986 • 213 citations

Mitochondrial damage in muscle occurs after marked depletion of glutathione and is prevented by giving glutathione monoester.

1989 • 206 citations

Inhibition of glutathione synthesis in the newborn rat: a model for endogenously produced oxidative stress.

1991 • 194 citations

Inactivation of the human CuZn superoxide dismutase during exposure to O2− and H2O2

1981 • 176 citations

Critical role of sulfhydryl group(s) in ATP‐dependent Ca²⁺ sequestration by the plasma membrane fraction from rat liver

1983 • 172 citations

The metabolism of menadione impairs the ability of rat liver mitochondria to take up and retain calcium.

1982 • 159 citations

Dechlorination of l-phenylalanine mustard by sensitive and resistant tumor cells and its relationship to intracellular glutathione content

1983 • 154 citations

Glutathione metabolism in the lung: inhibition of its synthesis leads to lamellar body and mitochondrial defects.

1989 • 153 citations

Oxygen radicals in biology and medicine

1989 • 112 citations

Glutathione ester prevents buthionine sulfoximine-induced cataracts and lens epithelial cell damage.

1989 • 111 citations

Proximate Composition, Mineral Content, and Fatty Acids of Catfish (Ictalurus punctatus, Rafinesque) for Different Seasons and Cooking Methods

1985 • 85 citations

Chemosensitization of L-phenylalanine mustard by the thiol-modulating agent buthionine sulfoximine.

1987 • 84 citations

Glutathione Centennial : molecular perspectives and clinical implications

1989 • 74 citations

The interaction of reduced glutathione with active oxygen species generated by xanthine-oxidase-catalyzed metabolism of xanthine

1985 • 72 citations

Lipid peroxidation, protein thiols and calcium homeostasis in bromobenzene-induced liver damage

1987 • 69 citations

Effects of methionine sulfoximine analogs on the synthesis of glutamine and glutathione: possible chemotherapeutic implications.

1979 • 64 citations

Production of thiol groups and retention of calcium ions by cardiac mitochondria

1980 • 44 citations

Effect of paraquat on serum angiotensin converting enzyme.

1980 • 39 citations

Increased Melphalan Activity in Intracranial Human Medulloblastoma and Glioma Xenografts Following Buthionine Sulfoximine-Mediated Glutathione Depletion

1989 • 34 citations

Lung damage induced by butylated hydroxytoluene in mice. Biochemical, cellular, and morphologic characterization.

1984 • 32 citations

Effect of systemic glutathione depletion by buthionine sulfoximine on sensitivity of murine bladder cancer to cytotoxic agents

1989 • 31 citations

A ‘dehydroascorbic acid reductase’ factor in guinea-pig tissues

1967 • 31 citations

ACQUIRED RESISTANCE OF TUMOR CELLS TO L-PHENYLALANINE MUSTARD: IMPLICATIONS FOR THE DESIGN OF A CLINICAL TRIAL INVOLVING GLUTATHIONE DEPLETION

1989 • 12 citations