Control of cell size through phosphorylation of upstream binding factor 1 by nuclear phosphatidylinositol 3-kinase

Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

2001 • 1,107 citations

Autonomous Control of Cell and Organ Size by CHICO, a Drosophila Homolog of Vertebrate IRS1–4

1999 • 838 citations

Systematic Identification of Pathways That Couple Cell Growth and Division in Yeast

2002 • 775 citations

Drosophila S6 Kinase: A Regulator of Cell Size

1999 • 710 citations

The IRS-signalling system: A network of docking proteins that mediate insulin action

1998 • 693 citations

Disruption of the p70s6k/p85s6k gene reveals a small mouse phenotype and a new functional S6 kinase

1998 • 636 citations

Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor.

1993 • 554 citations

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1998 • 523 citations

The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth.

1996 • 492 citations

Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1.

1993 • 452 citations

mTOR-Dependent Regulation of Ribosomal Gene Transcription Requires S6K1 and Is Mediated by Phosphorylation of the Carboxy-Terminal Activation Domain of the Nucleolar Transcription Factor UBF†

2003 • 434 citations

IRS-1: Essential for Insulin- and IL-4-Stimulated Mitogenesis in Hematopoietic Cells

1993 • 401 citations

Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB

1999 • 368 citations

Genetics of mouse growth.

1998 • 342 citations

Activity of RNA polymerase I transcription factor UBF blocked by Rb gene product

1995 • 324 citations

Tcl1 enhances Akt kinase activity and mediates its nuclear translocation

2000 • 300 citations

Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K

2002 • 293 citations

Insulin receptor substrate-1 mediates phosphatidylinositol 3'-kinase and p70S6k signaling during insulin, insulin-like growth factor-1, and interleukin-4 stimulation.

1994 • 257 citations

An Immediate Response of Ribosomal Transcription to Growth Factor Stimulation in Mammals Is Mediated by ERK Phosphorylation of UBF

2001 • 240 citations

Regulation of Mammalian Ribosomal Gene Transcription by RNA Polymerase I

1998 • 235 citations

Promotion and Regulation of Ribosomal Transcription in Eukaryotes by RNA Polymerase

1995 • 212 citations

The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system

2002 • 183 citations

Phosphorylation by G1-specific cdk-cyclin complexes activates the nucleolar transcription factor UBF

1999 • 179 citations

Cell division from a genetic perspective

1978 • 167 citations

Phosphorylation of UBF at serine 388 is required for interaction with RNA polymerase I and activation of rDNA transcription

2001 • 123 citations

Activation of mammalian ribosomal gene transcription requires phosphorylation of the nucleolar transcription requires phosphorylation of the nucleolar trasnscription factor UBF

1995 • 108 citations

Regulation of RNA Polymerase I Transcription in Yeast and Vertebrates

1998 • 108 citations

Pleiotropic Insulin Signals are Engaged by Multisite Phosphorylation of IRS-1

1993 • 107 citations

Insulin Receptor Substrate-1, p70S6K, and Cell Size in Transformation and Differentiation of Hemopoietic Cells

2000 • 105 citations

Lipid kinase and protein kinase activities of G-protein-coupled phosphoinositide 3-kinase γ: structure–activity analysis and interactions with wortmannin

1997 • 102 citations

Coactivator and Promoter-Selective Properties of RNA Polymerase I TAFs

1995 • 97 citations

Insulin-Like Growth Factor I Receptor Signaling and Nuclear Translocation of Insulin Receptor Substrates 1 and 2

2003 • 96 citations

Tcl1 enhances Akt kinase activity and mediates its nuclear translocation

2000 • 94 citations

Postnatal Growth Responses to Insulin-Like Growth Factor I in Insulin Receptor Substrate-1-Deficient Mice1

1999 • 80 citations

Nuclear Translocation of Insulin Receptor Substrate-1 by Oncogenes And Igf-I

2002 • 79 citations

The interferon-inducible nucleolar p204 protein binds the ribosomal RNA-specific UBF1 transcription factor and inhibits ribosomal RNA transcription

1999 • 75 citations

Novel cell cycle control of RNA synthesis in yeast

1978 • 72 citations

Dissociation between resistance to apoptosis and the transformed phenotype in IGF-I receptor signaling

1999 • 60 citations

Phosphorylation of the rRNA transcription factor upstream binding factor promotes its association with TATA binding protein

1998 • 43 citations

Intracellular redistribution of nuclear and nucleolar proteins during differentiation of 32D murine hemopoietic cells

2003 • 38 citations

Inhibition of RNA polymerase I transcription in differentiated myeloid leukemia cells by inactivation of selectivity factor 1.

2000 • 24 citations