Lack of tumorigenicity of interleukin 4 autocrine growing cells seems related to the anti-tumor function of interleukin 4

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

1988 • 1,698 citations

Autocrine growth factors and cancer

1985 • 1,462 citations

DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

1979 • 1,339 citations

Murine interleukin-4 displays potent anti-tumor activity in vivo

1989 • 790 citations

Monoclonal cytolytic T-cell lines.

1979 • 364 citations

Constitutive synthesis of interleukin-3 by leukaemia cell line WEHI-3B is due to retroviral insertion near the gene

1985 • 333 citations

Derivation of a T cell line that is highly responsive to IL-4 and IL-2 (CT.4R) and of an IL-2 hyporesponsive mutant of that line (CT.4S).

1989 • 289 citations

Expression of a hemopoietic growth factor cDNA in a factor-dependent cell line results in autonomous growth and tumorigenicity

1985 • 273 citations

Autocrine stimulation after transfer of the granulocyte/macrophage colony-stimulating factor gene and autonomous growth are distinct but interdependent steps in the oncogenic pathway.

1987 • 161 citations

Autocrine growth and tumorigenicity of interleukin 2-dependent helper T cells transfected with IL-2 gene.

1989 • 141 citations

Retroviral expression of the human IL-2 gene in a murine T cell line results in cell growth autonomy and tumorigenicity.

1987 • 103 citations

Retroviral transfer and expression of the interleukin-3 gene in hemopoietic cells.

1987 • 64 citations

DNA rearrangement and constitutive expression of the interleukin 6 gene in a mouse plasmacytoma.

1990 • 64 citations

Retroviral interleukin 4 gene transfer into an interleukin 4‐dependent cell line results in autocrine growth but not in tumorigenicity

1990 • 32 citations

A retroviral expression vector containing murine immunoglobullin heavy chain promoter/enhancer

1988 • 19 citations