Methylenetetrahydrofolate Reductase Gene Polymorphism and Ischemic Stroke in Japanese

Hyperhomocysteinemia: An Independent Risk Factor for Vascular Disease

1991 • 2,191 citations

A Prospective Study of Plasma Homocyst(e)ine and Risk of Myocardial Infarction in US Physicians

1992 • 1,686 citations

Relation Between Folate Status, a Common Mutation in Methylenetetrahydrofolate Reductase, and Plasma Homocysteine Concentrations

1996 • 1,423 citations

The natural history of homocystinuria due to cystathionine beta-synthase deficiency.

1985 • 1,251 citations

Association between Plasma Homocysteine Concentrations and Extracranial Carotid-Artery Stenosis

1995 • 1,244 citations

Special report from the National Institute of Neurological Disorders and Stroke. Classification of cerebrovascular diseases III.

1990 • 1,206 citations

Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection

1987 • 1,072 citations

Hyperhomocysteinemia as a Risk Factor for Deep-Vein Thrombosis

1996 • 1,034 citations

Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men

1995 • 899 citations

Heterozygosity for Homocystinuria in Premature Peripheral and Cerebral Occlusive Arterial Disease

1985 • 739 citations

Homocysteine and vascular disease

1996 • 694 citations

Homocysteine and coronary atherosclerosis

1996 • 544 citations

Prevalence of hyperhomocyst(e)inemia in patients with peripheral arterial occlusive disease.

1989 • 510 citations

Methylenetetrahydrofolate Reductase Polymorphism, Plasma Folate, Homocysteine, and Risk of Myocardial Infarction in US Physicians

1996 • 496 citations

Plasma homocyst(e)ine, folate, and vitamin B-12 concentrations and risk for early-onset coronary artery disease

1994 • 386 citations

Analysis of Risk Factors for Stroke in a Cohort of Men Born in 1913

1987 • 343 citations

Elevated plasma homocyst(e)ine concentration as a possible independent risk factor for stroke.

1990 • 311 citations

Effects of vitamin B12, folate, and vitamin B6 supplements in elderly people with normal serum vitamin concentrations

1995 • 296 citations

The Effects of Folic Acid Supplementation on Plasma Total Homocysteine Are Modulated by Multivitamin Use and Methylenetetrahydrofolate Reductase Genotypes

1997 • 277 citations

Genetic Polymorphism of 5,10-Methylenetetrahydrofolate Reductase (MTHFR) as a Risk Factor for Coronary Artery Disease

1997 • 264 citations

Determinants and vitamin responsiveness of intermediate hyperhomocysteinemia (> or = 40 micromol/liter). The Hordaland Homocysteine Study.

1996 • 263 citations

Hyperhomocysteinaemia in stroke: prevalence, cause, and relationships to type of stroke and stroke risk factors

1992 • 261 citations

Diabetes and Cardiovascular Disease in a Prospective Population Survey in Japan: The Hisayama Study

1996 • 257 citations

Homocysteine and Risk of Premature Coronary Heart Disease

1996 • 242 citations

Common Mutation in Methylenetetrahydrofolate Reductase

1996 • 226 citations

Plasma homocysteine in acute myocardial infarction: homocysteine‐lowering effect of folic acid

1995 • 212 citations

Plasma homocyst(e)ine as a risk factor for early familial coronary artery disease

1994 • 180 citations

A Common Polymorphism in the Methylenetetrahydrofolate Reductase Gene, Homocysteine, and Ischemic Cerebrovascular Disease

1997 • 178 citations

Distribution in Healthy and Coronary Populations of the Methylenetetrahydrofolate Reductase (MTHFR) C ₆₇₇ T Mutation

1996 • 173 citations

Cigarette Smoking and Stroke in a Cohort of U.S. Male Physicians

1994 • 150 citations

Genetic Polymorphism of Methylenetetrahydrofolate Reductase and Myocardial Infarction

1996 • 145 citations

Stroke trends in Japan

1993 • 44 citations

Genes for ischaemic stroke: strategies for their detection

1996 • 41 citations

Cerebrovascular disorder of Japanese.

1996 • 9 citations

[Classification of ischemic stroke and frequency distribution].

1993 • 4 citations