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Cannabinoid receptor localization in brain.

1990 • 2,248 citations

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

1998 • 1,931 citations

SR141716A, a potent and selective antagonist of the brain cannabinoid receptor

1994 • 1,743 citations

Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system

1998 • 1,549 citations

A Family of cAMP-Binding Proteins That Directly Activate Rap1

1998 • 1,351 citations

Molecular and Cellular Basis of Addiction

1997 • 1,324 citations

Localization of cannabinoid receptor mRNA in rat brain

1993 • 623 citations

Cannabis: pharmacology and toxicology in animals and humans

1996 • 490 citations

A review of differences between basal ganglia and cerebellar control of movements as revealed by functional imaging studies

1998 • 454 citations

Cyclic AMP Mediates a Presynaptic Form of LTP at Cerebellar Parallel Fiber Synapses

1996 • 444 citations

Opiate withdrawal and the rat locus coeruleus: behavioral, electrophysiological, and biochemical correlates

1990 • 442 citations

Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs

1991 • 403 citations

Isolation and structure of .DELTA.+- tetrahydrocannabinol and other neutral cannabinoids from hashish

1971 • 356 citations

Involvement of cAMP-Dependent Protein Kinase in the Nucleus Accumbens in Cocaine Self-Administration and Relapse of Cocaine-Seeking Behavior

1998 • 325 citations

CREB (cAMP Response Element-Binding Protein) in the Locus Coeruleus: Biochemical, Physiological, and Behavioral Evidence for a Role in Opiate Dependence

1997 • 298 citations

Melatonin Production: Proteasomal Proteolysis in Serotonin N -Acetyltransferase Regulation

1998 • 284 citations

Acute and chronic opiate-regulation of adenylate cyclase in brain: specific effects in locus coeruleus.

1988 • 280 citations

Cellular mechanisms of cerebellar LTD

1998 • 265 citations

Novel (Rp)-cAMPS Analogs as Tools for Inhibition of cAMP-kinase in Cell Culture

1995 • 236 citations

Cannabinoids decrease excitatory synaptic transmission and impair long‐term depression in rat cerebellar Purkinje cells

1998 • 227 citations

Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3',5'-cyclic phosphorothioates.

1990 • 220 citations

Behavioural and biochemical evidence for signs of abstinence in mice chronically treated with Δ‐9‐tetrahydrocannabinol

1998 • 191 citations

Physical withdrawal in rats tolerant to Δ9-tetrahydrocannabinol precipitated by a cannabinoid receptor antagonist

1995 • 170 citations

Impaired Cerebellar Long-Term Potentiation in Type I Adenylyl Cyclase Mutant Mice

1998 • 161 citations

Dependence on delta 9-tetrahydrocannabinol: studies on precipitated and abrupt withdrawal.

1996 • 158 citations

Calmodulin-regulated adenylyl cyclases and neuromodulation

1997 • 138 citations

Opposite Modulation of Opiate Withdrawal Behaviors on Microinfusion of a Protein Kinase A Inhibitor Versus Activator into the Locus Coeruleus or Periaqueductal Gray

1997 • 129 citations

CB1 receptor antagonist precipitates withdrawal in mice exposed to Delta9-tetrahydrocannabinol.

1998 • 123 citations

Visualization of Cyclic AMP–Regulated Presynaptic Activity at Cerebellar Granule Cells

1998 • 112 citations

Neuronal localization of cannabinoid receptors and second messengers in mutant mouse cerebellum

1991 • 106 citations

The cerebellum: an overview

1998 • 106 citations

Discrete expression of Ca²⁺/calmodulin‐sensitive and Ca²⁺ ‐insensitive adenylyl cyclases in the rat brain

1993 • 86 citations

A role for the cerebellum in the control of limb movement velocity

1998 • 76 citations

Regulation of Adenylyl Cyclase Isozymes on Acute and Chronic Activation of Inhibitory Receptors

1998 • 72 citations

(R_P)‐cAMPS inhibits the cAMP‐dependent protein kinase by blocking the cAMP‐induced conformational transition

1995 • 72 citations

Effects of SR 141716A after acute or chronic cannabinoid administration in dogs

1998 • 71 citations

The cerebellum and motor learning

1992 • 70 citations

Cannabinoid receptors: G-protein-mediated signal transduction mechanisms.

1993 • 54 citations

Angiotensin and salt appetite of BALB/c mice

1990 • 42 citations

Regulation of adenylate cyclase by cannabinoid drugs

1989 • 36 citations

Regulation of cAMP-dependent protein kinase subunit expression in CATH.a and SH-SY5Y cells.

1998 • 30 citations

Stimulation of anandamide biosynthesis in N-18TG2 neuroblastoma cells by δ9-tetrahydrocannabinol (THC)

1995 • 22 citations

Quantitation of rodent catalepsy by a computer-imaging technique

1992 • 22 citations