The properties of the secretagogue-evoked chloride current in mouse pancreatic acinar cells

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Cytosolic Ca2+ gradients triggering unidirectional fluid secretion from exocrine pancreas

1990 • 393 citations

Subcellular distribution of Ca2+ release channels underlying Ca2+ waves and oscillations in exocrine pancreas

1993 • 357 citations

Anion selectivity in biological systems

1977 • 297 citations

Cytoplasmic Ca2+ oscillations evoked by receptor stimulation, G-protein activation, internal application of inositol trisphosphate or Ca2+: simultaneous microfluorimetry and Ca2+ dependent Cl- current recording in single pancreatic acinar cells.

1990 • 291 citations

Calcium‐dependent chloride currents in isolated cells from rat lacrimal glands.

1986 • 253 citations

Genomic Cloning, Molecular Characterization, and Functional Analysis of Human CLCA1, the First Human Member of the Family of Ca2+-Activated Cl−Channel Proteins

1998 • 245 citations

Molecular cloning and transmembrane structure of hCLCA2 from human lung, trachea, and mammary gland

1999 • 159 citations

Activation of calcium-dependent chloride channels in rat parotid acinar cells.

1996 • 154 citations

Molecular and Functional Characterization of a Calcium-sensitive Chloride Channel from Mouse Lung

1998 • 142 citations

Acetylcholine stimulates a Ca2+-dependent Cl? conductance in mouse lacrimal acinar cells

1985 • 107 citations

Activation of nonselective cation channels by physiological cholecystokinin concentrations in mouse pancreatic acinar cells.

1992 • 90 citations

Single calcium-dependent cation channels in mouse pancreatic acinar cells

1984 • 88 citations

The murine calcium-sensitive chloride channel (mCaCC) is widely expressed in secretory epithelia and in other select tissues

1998 • 84 citations

Secretion of fluid and amylase in the perfused rat pancreas.

1977 • 73 citations

Pancreatic acinar cells: localization of acetylcholine receptors and the importance of chloride and calcium for acetylcholine‐evoked depolarization

1977 • 70 citations

Activation of nonselective cation channels in the basolateral membrane of rat distal colon crypt cells by prostaglandin E2

1992 • 68 citations

Pancreatic acinar cells: the acetylcholine equilibrium potential and its ionic dependency

1977 • 64 citations

Calcium-activated chloride conductance in a pancreatic adenocarcinoma cell line of ductal origin (HPAF) and in freshly isolated human pancreatic duct cells

1998 • 56 citations

Short pulses of acetylcholine stimulation induce cytosolic Ca2+ signals that are excluded from the nuclear region in pancreatic acinar cells

1996 • 56 citations

A Ca2+-activated Cl? current in sheep parotid secretory cells

1993 • 52 citations

Ca²⁺ and cAMP‐activated Cl⁻ conductances mediate Cl⁻ secretion in a mouse renal inner medullary collecting duct cell line

2000 • 50 citations

Differences in regulation of Ca²⁺-activated Cl⁻channels in colonic and parotid secretory cells

1998 • 49 citations

Chloride channels in the luminal membrane of rat pancreatic acini

1997 • 36 citations

Mouse pancreatic acinar cells: the anion selectivity of the acetylcholine‐opened chloride pathway.

1980 • 35 citations

A Bicarbonate- and Weak Acid-permeable Chloride Conductance Controlled by Cytosolic Ca 2+ and ATP in Rat Submandibular Acinar Cells

1996 • 29 citations

Relationship between intracellular calcium and its muffling measured by calcium iontophoresis in snail neurones.

1996 • 29 citations

The relationship between acetylcholine-evoked Ca2+-dependent current and the Ca2+ concentrations in the cytosol and the lumen of the endoplasmic reticulum in pancreatic acinar cells

1999 • 17 citations

A Bimodal Pattern of InsP3-Evoked Elementary Ca2+ Signals in Pancreatic Acinar Cells

2000 • 16 citations

A voltage-sensitive transient potassium current in mouse pancreatic acinar cells

1994 • 12 citations

Ca²⁺-activated Cl⁻channels Focus on “Molecular cloning and transmembrane structure of hCLCA2 from human lung, trachea, and mammary gland”

1999 • 11 citations