Both donor and recipient NOD2/CARD15 mutations associate with transplant-related mortality and GvHD following allogeneic stem cell transplantation

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

2001 • 5,526 citations

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

2001 • 4,997 citations

CLINICAL MANIFESTATIONS OF GRAFT-VERSUS-HOST DISEASE IN HUMAN RECIPIENTS OF MARROW FROM HL-A-MATCHED SIBLING DONOR,S

1974 • 3,686 citations

Host Recognition of Bacterial Muramyl Dipeptide Mediated through NOD2

2003 • 1,651 citations

The primacy of the gastrointestinal tract as a target organ of acute graft-versus-host disease: rationale for the use of cytokine shields in allogeneic bone marrow transplantation

2000 • 702 citations

CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells

2003 • 632 citations

The Genetics of Inflammatory Bowel Disease

2007 • 572 citations

Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis

2003 • 421 citations

Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: a cohort study

2002 • 413 citations

Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan

2003 • 403 citations

The genetics of inflammatory bowel disease

2003 • 363 citations

Tumor necrosis factor- alpha production to lipopolysaccharide stimulation by donor cells predicts the severity of experimental acute graft-versus-host disease.

1998 • 342 citations

Peyer's patch is the essential site in initiating murine acute and lethal graft-versus-host reaction

2003 • 289 citations

LPS antagonism reduces graft-versus-host disease and preserves graft-versus-leukemia activity after experimental bone marrow transplantation

2001 • 288 citations

Nods: a family of cytosolic proteins that regulate the host response to pathogens

2002 • 250 citations

CARD15: a Pleiotropic Autoimmune Gene That Confers Susceptibility to Psoriatic Arthritis

2003 • 170 citations

Card15 gene overexpression in mononuclear and epithelial cells of the inflamed Crohn's disease colon

2003 • 150 citations

Role of Bacterial Microflora in Development of Intestinal Lesions From Graft-Versus-Host Reaction

1977 • 132 citations

The role of endotoxin and the innate immune response in the pathophysiology of acute graft versus host disease

2002 • 99 citations

Role of NOD2 variants in spondylarthritis

2002 • 84 citations

Rapid achievement of complete donor chimerism and low regimen-related toxicity after reduced conditioning with fludarabine, carmustine, melphalan and allogeneic transplantation

2000 • 70 citations

Cytokines, viruses, and graft-versus-host disease

2002 • 62 citations

Fulminant Crohn's colitis after allogeneic stem cell transplantation

2003 • 59 citations

Familial and genetic aspects of spondyloarthropathy

2003 • 42 citations

The three most common CARD15 mutations associated with Crohn's disease and the chromosome 16 susceptibility locus for systemic lupus erythematosus

2003 • 37 citations

Observations on the role of endotoxin in graft-versus-host disease.

1988 • 14 citations