Biochemical and functional consequences of dissociation of the platelet membrane glycoprotein IIb-IIIa complex

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

A simple technique for eliminating interference by detergents in the Lowry method of protein determination

1975 • 962 citations

A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa.

1983 • 780 citations

Platelet hypersensitivity induced by cholesterol incorporation.

1975 • 464 citations

Platelet plasma membrane glycoproteins. Evidence for the presence of nonequivalent disulfide bonds using nonreduced-reduced two-dimensional gel electrophoresis.

1977 • 451 citations

Identification of membrane proteins mediating the interaction of human platelets

1980 • 383 citations

Correlation between fibrinogen binding to human platelets and platelet aggregability

1980 • 365 citations

Purification of glycoproteins IIb and III from human platelet plasma membranes and characterization of a calcium-dependent glycoprotein IIb-III complex.

1982 • 337 citations

Inhibition of fibrinogen binding to stimulated human platelets by a monoclonal antibody.

1983 • 280 citations

Effect of trypsin on the exposed polypeptides and glycoproteins in the human platelet membrane

1972 • 269 citations

The formation of Ca++-dependent complexes of platelet membrane glycoproteins IIb and IIIa in solution as determined by crossed immunoelectrophoresis

1981 • 261 citations

Identification of two structurally and functionally distinct sites on human platelet membrane glycoprotein IIb-IIIa using monoclonal antibodies.

1983 • 241 citations

Calcium cation regulation of glycoprotein IIb-IIIa complex formation in platelet plasma membranes.

1983 • 144 citations

Nonreversible loss of platelet aggregability induced by calcium deprivation

1978 • 112 citations

Changes in surface-bound and exchangeable calcium during platelet activation.

1982 • 77 citations

Electrophoresis and electrofocusing on polyacrylamide gel in the study of native macromolecules

1980 • 73 citations

Crossed immunoelectrophoresis of human platelet membranes. The major antigen consists of a complex of glycoproteins, GPIIb and GPIIIa, held together by Ca2+ and missing in Glanzmann's thrombasthenia.

1982 • 61 citations

Involvement of divalent cations in the complex between the platelet glycoproteins IIb and IIIa

1982 • 52 citations

Characterization of the Insulin Receptor and Insulin-Degrading Activity from Human Lymphocytes by Quantitative Polyacrylamide Gel Electrophoresis*

1980 • 41 citations

The Combining Ability of Glycoproteins IIb, IIIa and Ca2+ in EDTA-Treated Nonaggregable Platelets

1983 • 20 citations

Identification of photoaffinity labeled insulin receptor proteins by linear polyacrylamide gradient gel electrophoresis under non‐denaturing conditions

1980 • 20 citations