Clozapine Preferentially Increases Dopamine Release in the Rhesus Monkey Prefrontal Cortex Compared with the Caudate Nucleus

Clozapine for the Treatment-Resistant Schizophrenic

1988 • 4,030 citations

Physiologic Dysfunction of Dorsolateral Prefrontal Cortex in Schizophrenia

1986 • 2,026 citations

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

1991 • 2,008 citations

Dopamine in schizophrenia: a review and reconceptualization

1991 • 1,963 citations

Antipsychotic drug doses and neuroleptic/dopamine receptors

1976 • 1,623 citations

Dopamine Receptor Binding Enhancement Accompanies Lesion-Induced Behavioral Supersensitivity

1977 • 716 citations

Dopaminergic innervation of the cerebral cortex: unexpected differences between rodents and primates

1991 • 584 citations

5-Hydroxytryptamine _2A serotonin receptors in the primate cerebral cortex: Possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites

1998 • 510 citations

Localization of dopamine D4 receptors in GABAergic neurons of the primate brain

1996 • 494 citations

Chapter 3 Qualitative and quantitative comparison of the prefrontal cortex in rat and in primates, including humans

1991 • 457 citations

Dopamine receptor sequences. Therapeutic levels of neuroleptics occupy D2 receptors, clozapine occupies D4.

1992 • 445 citations

Acute Effects of Typical and Atypical Antipsychotic Drugs on the Release of Dopamine from Prefrontal Cortex, Nucleus Accumbens, and Striatum of the Rat: An In Vivo Microdialysis Study

1990 • 407 citations

Enduring Cognitive Deficits and Cortical Dopamine Dysfunction in Monkeys After Long-Term Administration of Phencyclidine

1997 • 401 citations

The Prefrontal Cortex Regulates the Basal Release of Dopamine in the Limbic Striatum: An Effect Mediated by Ventral Tegmental Area

1996 • 365 citations

Characterization of the Dopaminergic Innervation of the Primate Frontal Cortex Using a Dopamine-specific Antibody

1993 • 283 citations

Cortical Regulation of Subcortical Dopamine Release: Mediation via the Ventral Tegmental Area

1995 • 260 citations

Differential effects of chronic antipsychotic drug treatment on extracellular glutamate and dopamine concentrations

1994 • 203 citations

Clozapine increases dopamine release in prefrontal cortex by 5-HT1A receptor activation

1997 • 201 citations

Effects of clozapine on cognitive function in schizophrenia.

1994 • 200 citations

Pharmacological actions of the atypical antipsychotic drug clozapine: A review

1996 • 181 citations

A common action of clozapine, haloperidol, and remoxipride on D1- and D2-dopaminergic receptors in the primate cerebral cortex.

1994 • 175 citations

Neonatal lesions of the medial temporal lobe disrupt prefrontal cortical regulation of striatal dopamine

1998 • 156 citations

Does clozapine cause tardive dyskinesia?

1993 • 140 citations

Down-regulation of the D1 and D5 dopamine receptors in the primate prefrontal cortex by chronic treatment with antipsychotic drugs.

1997 • 129 citations

Actions of clozapine and haloperidol on the extracellular levels of excitatory amino acids in the prefrontal cortex and striatum of conscious rats

1993 • 118 citations

The selective 5-HT2A receptor antagonist, MDL 100,907, increases dopamine efflux in the prefrontal cortex of the rat

1995 • 118 citations

Augmentation of prefrontal cortical monoaminergic activity inhibits dopamine release in the caudate nucleus: Anin vivo neurochemical assessment in the rhesus monkey

1995 • 93 citations

Ipsilateral cortical connections of granular frontal cortex in the strepsirhine primateGalago, with comparative comments on anthropoid primates

1991 • 89 citations

The Effects of Haloperidol and Clozapine on Extracellular GABA Levels in the Prefrontal Cortex of the Rat: An in vivo Microdialysis Study

1994 • 82 citations

5‐HT_1a agonist ±‐ 8‐OH‐DPAT modulates basal and stress‐induced changes in medial prefrontal cortical dopamine

1994 • 76 citations

Local infusion of the serotonin antagonists ritanserin or ICS 205,930 increases in vivo dopamine release in the rat medial prefrontal cortex

1996 • 66 citations

In vivo assessment of basal and drug‐induced dopamine release in cortical and subcortical regions of the anesthetized primate

1993 • 64 citations

A common action of clozapine, haloperidol, and remoxipride on D1- and D2-dopaminergic receptors in the primate cerebral cortex

1994 • 54 citations

Preferential activation of dopamine overflow in prefrontal cortex produced by chronic clozapine treatment

1994 • 49 citations

Molecular cloning and expression of the rhesus macaque D1 dopamine receptor gene.

1992 • 37 citations

The atypical antipsychotic drug amperozide enhances rat cortical and striatal dopamine efflux

1993 • 33 citations

Methodology of microdialysis of neostriatum in hemiparkinsonian nonhuman primates

1990 • 23 citations

An improved methodology for routine in vivo microdialysis in non-human primates

1994 • 21 citations