Highly lytic CD8+, alpha beta T-cell receptor cytotoxic T cells with major histocompatibility complex (MHC) class I antigen-directed cytotoxicity in beta 2-microglobulin, MHC class I-deficient mice.

Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS)

1989 • 2,480 citations

T cell tolerance by clonal elimination in the thymus

1987 • 2,248 citations

Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis

1978 • 1,954 citations

The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides

1986 • 1,723 citations

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

1987 • 1,644 citations

β2-Microglobulin deficient mice lack CD4−8+ cytolytic T cells

1990 • 997 citations

Association of class I major histocompatibility heavy and light chains induced by viral peptides

1989 • 995 citations

Classification of human colorectal adenocarcinoma cell lines.

1976 • 943 citations

Normal Development of Mice Deficient in β ₂ M, MCClass I Proteins, and CD8 ⁺ T Cells

1990 • 885 citations

Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cells

1990 • 775 citations

Monoclonal Antibodies for Analysis of the HLA System

1979 • 745 citations

Chromosome 5 allele loss in human colorectal carcinomas

1987 • 566 citations

Hybrid antibodies can target sites for attack by T cells

1985 • 479 citations

Human colonic adenocarcinoma cells

1976 • 375 citations

Markedly decreased expression of class I histocompatibility antigens, protein, and mRNA in human small-cell lung cancer.

1985 • 358 citations

Specific targeting of cytotoxic T cells by anti-T3 linked to anti-target cell antibody

1985 • 339 citations

Influenza nucleoprotein-specific cytotoxic T-cell clones are protective in vivo.

1986 • 261 citations

N,N-dimethylformamide-induced alteration of cell culture characteristics and loss of tumorigenicity in cultured human colon carcinoma cells.

1979 • 261 citations

CD8+ T cells specific for a single nonamer epitope of Listeria monocytogenes are protective in vivo.

1992 • 260 citations

Striking paucity of HLA-A, B, C and beta 2-microglobulin on human neuroblastoma cell lines.

1983 • 257 citations

The Genetic Control of HLA‐A and B Antigens in Somatic Cell Hybrids: Requirement for β₂ Microglobulin

1978 • 222 citations

Hormonal control of human colon carcinoma cell growth in serum-free medium.

1980 • 219 citations

Beta 2-microglobulin is not required for cell surface expression of the murine class I histocompatibility antigen H-2Db or of a truncated H-2Db.

1986 • 212 citations

Production of stable cytolytic T‐cell clones directed against autologous human melanoma

1987 • 209 citations

Tumor and lymphoid cell lines from a patient with carcinoma of the colon for a cytotoxicity model.

1978 • 185 citations

Characterization of WiDr: A human colon carcinoma cell line

1979 • 171 citations

LCMV-Specific, Class II-Restricted Cytotoxic T Cells in β2-Microglobulin-Deficient Mice

1992 • 164 citations

Distribution of HLA class 1 antigens in normal human tissue and in mammary cancer.

1981 • 153 citations

Most gamma delta T cells develop normally in beta 2-microglobulin-deficient mice.

1992 • 147 citations

Functionally conformed free class I heavy chains exist on the surface of beta 2 microglobulin negative cells.

1992 • 146 citations

Skin graft rejection by beta 2-microglobulin-deficient mice.

1992 • 142 citations

The isolation and characterization of colorectal epithelial cell lines at different stages in malignant transformation from familial polyposis coli patients

1984 • 139 citations

The HLA system: structure and function.

1987 • 131 citations

A new colon carcinoma cell line (LIM1863) that grows as organoids with spontaneous differentiation into crypt-like structures in vitro.

1987 • 121 citations

Loss of HLA-A,B,C allele products and lymphocyte function-associated antigen 3 in colorectal neoplasia.

1989 • 119 citations

Establishment and characterization of human colorectal cancer cell lines.

1984 • 96 citations

Expression of major histocompatibility antigens and nature of inflammatory cellular infiltrate in ovarian neoplasms

1983 • 81 citations

Interleukin 2 abrogates the nonresponsive state of T cells expressing a forbidden T cell receptor repertoire and induces autoimmune disease in neonatally thymectomized mice.

1991 • 81 citations

Rescue of Daudi cell HLA expression by transfection of the mouse beta 2-microglobulin gene.

1988 • 79 citations

Protection against two spontaneous mouse leukemias conferred by immunogenic variants obtained by mutagenesis.

1983 • 79 citations

MHC antigens and cancer: implications for T-cell surveillance

1992 • 68 citations

REJECTION OF ASCITES TUMOR ALLOGRAFTS

1972 • 65 citations

EVIDENCE THAT RAT RENAL ALLOGRAFTS ARE REJECTED BY CYTOTOXIC T CELLS AND NOT BY NONSPECIFIC EFFECTORS

1985 • 62 citations

Cytotoxic Lymphocytes in the Absence of Detectable Antibody

1973 • 61 citations

Genetic Characteristics of the HeLa Cell

1976 • 59 citations

HLA CLASS I NUCLEOTIDE SEQUENCES, 1991

1991 • 57 citations

Responsiveness of three newly established human colorectal cancer cell lines to transforming growth factors beta 1 and beta 2.

1992 • 57 citations

Establishment and characterisation of six human colorectal adenocarcinoma cell lines

1986 • 52 citations

Beta 2-microglobulin gene is mutated in a human colon cancer cell line (HCT) deficient in the expression of HLA class I antigens on the cell surface.

1992 • 50 citations

The conformation of Ld induced by beta 2-microglobulin is fixed during de novo synthesis and irreversible by exchange or dissociation.

1989 • 47 citations

A sensitive micro-immunoassay using β-galactosidase/ anti-β-galactosidase complexes

1987 • 29 citations

Variation in HLA Expression on Tumors: An Escape from Immune Response

1989 • 22 citations

Expression of MHC-class-I antigens in human carcinomas and sarcomas analyzed by isoelectric focusing

1991 • 20 citations

c-Ha-ras not c-Ki-ras activation in three colon tumour cell lines

1985 • 9 citations