Retroviral vector-producer cell-mediated in vivo gene transfer of TIMP-3 restricts angiogenesis and neuroblastoma growth in mice

Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma

1991 • 5,657 citations

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1991 • 2,774 citations

Metalloproteinases and their inhibitors in matrix remodeling

1990 • 1,627 citations

Tissue inhibitors of metalloproteinases: structure, regulation and biological functions.

1997 • 1,510 citations

Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

1994 • 1,249 citations

Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells

1997 • 694 citations

The Matrix Metalloproteinases and Their Inhibitors

1992 • 604 citations

Matrix metalloproteinases

2000 • 533 citations

Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues.

1994 • 485 citations

Flk-1 as a target for tumor growth inhibition.

1996 • 321 citations

Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP-3

1999 • 285 citations

Angiopoietin-2 is related to tumor angiogenesis in gastric carcinoma: possible in vivo regulation via induction of proteases.

2001 • 269 citations

Adenovirus-mediated gene delivery of tissue inhibitor of metalloproteinases-3 inhibits invasion and induces apoptosis in melanoma cells.

1998 • 268 citations

Inhibition of angiogenesis by tissue inhibitor of metalloproteinase-3.

1997 • 253 citations

Enforced Expression of the GATA-2 Transcription Factor Blocks Normal Hematopoiesis

1999 • 239 citations

Gene delivery to glioma cells in rat brain by grafting of a retrovirus packaging cell line

1990 • 195 citations

A review of tissue inhibitor of metalloproteinases-3 (TIMP-3) and experimental analysis of its effect on primary tumor growth

1996 • 149 citations

Inducible, High-Level Production of Infectious Murine Leukemia Retroviral Vector Particles Pseudotyped with Vesicular Stomatitis Virus G Envelope Protein

1995 • 136 citations

Enforced expression of tissue inhibitor of matrix metalloproteinase-3 affects functional capillary morphogenesis and inhibits tumor growth in a murine tumor model

2002 • 100 citations

INHIBITION OF MATRIX METALLOPROTEINASES THERAPEUTIC APPLICATIONS

1999 • 100 citations

An Improved Method for Generating Retroviral Producer Clones for Vectors Lacking a Selectable Marker Gene

1998 • 84 citations

Matrix metalloproteinases as emerging targets in anticancer therapy: status and prospects

2000 • 77 citations

Selection of transduced CD34+ progenitors and enzymatic correction of cells from Gaucher patients, with bicistronic vectors.

1995 • 61 citations

Retroviral vector-producer cell mediated angiogenesis inhibition restricts neuroblastoma growth in vivo

2000 • 18 citations