Stress-evoked opioid release inhibits pain in major depressive disorder

The prevalence and distribution of major depression in a national community sample: the National Comorbidity Survey

1994 • 1,417 citations

Chronic Pain-Associated Depression: Antecedent or Consequence of Chronic Pain? A Review

1997 • 1,052 citations

Regional Mu Opioid Receptor Regulation of Sensory and Affective Dimensions of Pain

2001 • 832 citations

Chronic pain and depression: Does the evidence support a relationship?

1985 • 743 citations

Explaining high rates of depression in chronic pain: A diathesis-stress framework.

1996 • 713 citations

Sex differences in pain perception

2005 • 580 citations

Parallel circuits mediating distinct emotional coping reactions to different types of stress

2001 • 491 citations

Gender differences in the responses to noxious stimuli

1995 • 475 citations

Regulation of Human Affective Responses by Anterior Cingulate and Limbic µ-Opioid Neurotransmission

2003 • 378 citations

Stress-induced analgesia: adaptive pain suppression

1986 • 370 citations

Pronociceptive and Antinociceptive Effects of Estradiol through Endogenous Opioid Neurotransmission in Women

2006 • 352 citations

First onset of common pain symptoms: a prospective study of depression as a risk factor

1993 • 345 citations

Stress-Induced Analgesia in Humans: Endogenous Opioids and Naloxone-Reversible Depression of Pain Reflexes

1981 • 329 citations

Perceived self-efficacy and pain control: Opioid and nonopioid mechanisms.

1987 • 317 citations

Naltrexone

1988 • 314 citations

Perceived self-efficacy and pain control: Opioid and nonopioid mechanisms.

1987 • 294 citations

Naloxone-Reversible Analgesic Response to Combat-Related Stimuli in Posttraumatic Stress Disorder

1990 • 292 citations

Perceived self-efficacy in coping with cognitive stressors and opioid activation.

1988 • 290 citations

Naloxone alters pain perception and somatosensory evoked potentials in normal subjects

1977 • 287 citations

Dysregulation of Endogenous Opioid Emotion Regulation Circuitry in Major Depression in Women

2006 • 277 citations

Perceived self-efficacy in coping with cognitive stressors and opioid activation.

1988 • 237 citations

Stress-induced hyperalgesia: animal models and putative mechanisms

2006 • 232 citations

Impact of Depression on Experimental Pain Perception: A Systematic Review of the Literature with Meta-Analysis

2003 • 221 citations

Lack of effect of naloxone on pain perception in humans

1976 • 191 citations

Endorphins: Naloxone Fails to Alter Experimental Pain or Mood in Humans

1978 • 184 citations

Relationship Between Clinical Pain Complaints and Pain Sensitivity in Patients With Depression and Panic Disorder

1999 • 184 citations

Interface of physical and emotional stress regulation through the endogenous opioid system and μ-opioid receptors

2005 • 146 citations

Pain activation of human supraspinal opioid pathways as demonstrated by [11C]-carfentanil and positron emission tomography (PET)

2002 • 132 citations

Negative affect and sensitization to pain

2002 • 120 citations

Analgesia to painful stimuli in affective illness

1979 • 113 citations

Theoretical review: altered pain regulatory systems in chronic pain

1999 • 109 citations

Review of naltrexone, a long-acting opiate antagonist.

1984 • 107 citations

Pain perception in depression: relationships to symptomatology and naloxone-sensitive mechanisms.

1994 • 103 citations

Cognitive-behavioural theories of helplessness/hopelessness: Valid models of depression?

2002 • 95 citations

μ-Opioid receptors and limbic responses to aversive emotional stimuli

2002 • 83 citations

Association of beta-endorphin with specific clinical symptoms of depression

1992 • 82 citations

Endorphins, opiates, and behavioural processes

1988 • 82 citations

Pain responsivity in major depression and bipolar disorder

1995 • 61 citations

Psychiatric Morbidity in Patients With Chronic Whiplash-Associated Disorder

2004 • 47 citations

Negative affect, pain and sex: The role of endogenous opioids

2007 • 46 citations

Endogenous opiates increase pain tolerance after stress in humans

1983 • 43 citations

Pain threshold is reduced in depression

1998 • 43 citations

Somatovegetative Changes in Stress‐Induced Analgesia in Man: An Electrophysiological and Pharmacological Study

1986 • 42 citations

The elevation of plasma β-endorphin levels in major depression

1993 • 41 citations

Opioid Regulation of Hypothalamic-Pituitary-Adrenal Function in Depression

1985 • 33 citations

Increased postoperative pain scores in chronic depression patients who take antidepressants

2002 • 30 citations

Real-Life Stress and Opioid-Mediated Analgesia in Novice Parachute Jumpers

2001 • 17 citations

The Effect of Subcutaneous Naloxone on Experimentally Induced Pain

2007 • 17 citations

The relationship between basal plasma B-endorphin levels and the severity of major depressive episode

2000 • 3 citations