Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans

A protein related to extracellular matrix proteins deleted in the mouse mutant reeler

1995 • 1,720 citations

Interneuron Migration from Basal Forebrain to Neocortex: Dependence on Dlx Genes

1997 • 1,421 citations

Glutamine Repeats and Neurodegeneration

2000 • 1,309 citations

Doublecortin Is a Microtubule-Associated Protein and Is Expressed Widely by Migrating Neurons

1999 • 1,297 citations

Isolation of a Miller–Dicker lissencephaly gene containing G protein β-subunit-like repeats

1993 • 1,067 citations

doublecortin, a Brain-Specific Gene Mutated in Human X-Linked Lissencephaly and Double Cortex Syndrome, Encodes a Putative Signaling Protein

1998 • 1,019 citations

Doublecortin Is a Developmentally Regulated, Microtubule-Associated Protein Expressed in Migrating and Differentiating Neurons

1999 • 974 citations

Central Nervous System

1981 • 920 citations

Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations

2000 • 867 citations

Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum

1999 • 857 citations

CENTRAL NERVOUS SYSTEM NEURONAL MIGRATION

1999 • 808 citations

Short GCG expansions in the PABP2 gene cause oculopharyngeal muscular dystrophy

1998 • 764 citations

A Novel CNS Gene Required for Neuronal Migration and Involved in X-Linked Subcortical Laminar Heterotopia and Lissencephaly Syndrome

1998 • 740 citations

In utero fate mapping reveals distinct migratory pathways and fates of neurons born in the mammalian basal forebrain

2001 • 702 citations

Origin of GABAergic neurons in the human neocortex

2002 • 682 citations

Distinct cortical migrations from the medial and lateral ganglionic eminences

2001 • 651 citations

Origin and Molecular Specification of Striatal Interneurons

2000 • 600 citations

Testosterone Formation and Metabolism During Male Sexual Differentiation in the Human Embryo

1974 • 592 citations

Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality

1998 • 571 citations

Mutations of the Homeobox Genes Dlx-1 and Dlx-2 Disrupt the Striatal Subventricular Zone and Differentiation of Late Born Striatal Neurons

1997 • 535 citations

Mouse Pitx2 deficiency leads to anomalies of the ventral body wall, heart, extra- and periocular mesoderm and right pulmonary isomerism

1999 • 458 citations

Mutations in the human ortholog of Aristaless cause X-linked mental retardation and epilepsy

2002 • 425 citations

Sorting of Striatal and Cortical Interneurons Regulated by Semaphorin-Neuropilin Interactions

2001 • 418 citations

The origin and migration of cortical neurones: new vistas

2000 • 392 citations

LIS1 and XLIS (DCX) mutations cause most classical lissencephaly, but different patterns of malformation

1998 • 352 citations

Differential Origins of Neocortical Projection and Local Circuit Neurons: Role of Dlx Genes in Neocortical Interneuronogenesis

1999 • 328 citations

Induction and Dorsoventral Patterning of the Telencephalon

2000 • 314 citations

LIS1 Regulates CNS Lamination by Interacting with mNudE, a Central Component of the Centrosome

2000 • 296 citations

ARX, a novel Prd-class-homeobox gene highly expressed in the telencephalon, is mutated in X-linked mental retardation

2002 • 279 citations

The battle of the sexes

2000 • 271 citations

Differences in the gyral pattern distinguish chromosome 17–linked and X-linked lissencephaly

1999 • 224 citations

Activation of CYP11A and CYP11B gene promoters by the steroidogenic cell-specific transcription factor, Ad4BP.

1993 • 209 citations

The adhesion molecule TAG-1 mediates the migration of cortical interneurons from the ganglionic eminence along the corticofugal fiber system

2001 • 196 citations

Expression of a novel aristaless related homeobox gene ‘Arx’ in the vertebrate telencephalon, diencephalon and floor plate

1997 • 177 citations

Holoprosencephaly due to mutations in ZIC2: alanine tract expansion mutations may be caused by parental somatic recombination

2001 • 177 citations

Neuronal migration

2001 • 168 citations

X‐linked lissencephaly with absent corpus callosum and ambiguous genitalia (XLAG): Clinical, magnetic resonance imaging, and neuropathological findings

2002 • 167 citations

Targeted mutagenesis of Lis1 disrupts cortical development and LIS1 homodimerization

2001 • 145 citations

Expression patterns of Brx1 (Rieg gene), Sonic hedgehog, Nkx2.2, Dlx1 and Arx during zona limitans intrathalamica and embryonic ventral lateral geniculate nuclear formation

1997 • 138 citations

X-linked lissencephaly with absent corpus callosum and ambiguous genitalia

1999 • 130 citations

New directions for neuronal migration

1998 • 126 citations

Dax-1 as One of the Target Genes of Ad4BP/SF-1

1999 • 119 citations

Bilateral opercular polymicrogyria

1989 • 89 citations

X‐linked pachygyria and agenesis of the corpus callosum: Evidence for an X chromosome lissencephaly locus

1994 • 67 citations

Adrenocortical and Gonadal Expression of the Mammalian Ftz-F1 Gene Encoding Ad4BP/SF-1 Is Independent of Pituitary Control

1998 • 42 citations

X-linked malformations of cortical development

2000 • 26 citations