Elevated serum interleukin-6 associated with a failur in B cell differentiation in common variable immunodeficiecy†

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

1986 • 2,137 citations

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

1988 • 1,698 citations

Identification of a T cell-derived b cell growth factor distinct from interleukin 2.

1982 • 1,095 citations

Excessive production of interleukin 6/B cell stimulatory factor‐2 in rheumatoid arthritis

1988 • 793 citations

The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells.

1988 • 791 citations

Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor.

1987 • 690 citations

Induction of β2-interferon by tumor necrosis factor: A homeostatic mechanism in the control of cell proliferation

1986 • 577 citations

Isolation and characterization of a mouse interleukin cDNA clone that expresses B-cell stimulatory factor 1 activities and T-cell- and mast-cell-stimulating activities.

1986 • 529 citations

Human interleukin-2 promotes proliferation of activated B cells via surface receptors similar to those of activated T cells

1984 • 375 citations

Idiopathic late-onset immunoglobulin deficiency

1976 • 365 citations

Human B-cell differentiation factor defined by an anti-peptide antibody and its possible role in autoantibody production.

1987 • 363 citations

Factors Affecting B-Cell Growth and Differentiation

1985 • 354 citations

Establishment of an interleukin 6 (IL 6)/B cell stimulatory factor 2‐dependent cell line and preparation of anti‐IL 6 monoclonal antibodies

1988 • 308 citations

Granulocyte colony-stimulating factor enhances interleukin 3-dependent proliferation of multipotential hemopoietic progenitors.

1988 • 296 citations

Atrial myxomas: a review of clinical experience in 40 patients.

1980 • 256 citations

Identification of alpha 2-macroglobulin as a carrier protein for IL-6.

1989 • 208 citations

Incidence of cancer in 98 patients with common varied immunodeficiency

1987 • 205 citations

Stimulation of immunoglobulin secretion in human B lymphocytes as a direct effect of high concentrations of IL 2.

1984 • 143 citations

The syndrome of immunoglobulin deficiency and pernicious anemia

1969 • 131 citations

Childhood common variable immunodeficiency with autoimmune disease

1986 • 127 citations

B-cell stimulatory factors (BSFs): Molecular structure, biological function, and regulation of expression

1987 • 100 citations

Production of B cell-stimulating factors by B cells in patients with systemic lupus erythematosus.

1988 • 92 citations

Production of a monoclonal antibody useful in the molecular characterization of murine T-cell-replacing factor/B-cell growth factor II.

1987 • 88 citations

Absence of antiviral activity in recombinant B cell stimulatory factor 2 (BSF-2)

1988 • 87 citations

Primary Acquired Agammaglobulinemia, with a Family History of Collagen Disease and Hematologic Disorders

1962 • 72 citations

Growth autonomy and tumorigenicity of interleukin 6-dependent B cells transfected with interleukin 6 cDNA.

1990 • 71 citations

Dysgammaglobulinemia in the Adult Manifested as Autoimmune Hemolytic Anemia

1963 • 66 citations

Stimulation of EBV-activated human B cells by monocytes and monocyte products. Role of IFN-beta 2/B cell stimulatory factor 2/IL-6.

1988 • 62 citations

Failure of B cells in common variable immunodeficiency to transit from proliferation to differentiation is associated with altered B cell surface-molecule display

1989 • 30 citations

Autoimmune blood dyscrasias in five patients with hypogammaglobulinemia: Response of neutropenia to vincristine

1981 • 29 citations

Factors Affecting B-Cell Growth and Differentiation

1985 • 25 citations

Idiopathic late-onset immunoglobulin deficiency. Clinical observations in 50 patients

1976 • 15 citations

Immunodeficiency, malabsorption and secretory diarrhea

1979 • 12 citations