Specific gene transfer mediated by lactosylated poly-L-lysine into hepatoma cells

Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides

1970 • 3,443 citations

Firefly luciferase gene: structure and expression in mammalian cells.

1987 • 3,088 citations

Human Hepatocellular Carcinoma Cell Lines Secrete the Major Plasma Proteins and Hepatitis B Surface Antigen

1980 • 2,034 citations

ACIDIFICATION OF THE ENDOCYTIC AND EXOCYTIC PATHWAYS

1986 • 1,977 citations

Carbohydrate-Specific Receptors of the Liver

1982 • 1,895 citations

Lectins as Cell Recognition Molecules

1989 • 1,204 citations

Firefly Luciferase Gene: Structure and Expression in Mammalian Cells

1987 • 924 citations

Receptor-mediated in vitro gene transformation by a soluble DNA carrier system.

1987 • 841 citations

Membrane fusion proteins of enveloped animal viruses

1983 • 670 citations

Transferrin-polycation conjugates as carriers for DNA uptake into cells.

1990 • 657 citations

Receptor-mediated gene delivery and expression in vivo.

1988 • 642 citations

Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts.

1982 • 569 citations

Viral and Cellular Membrane Fusion Proteins

1990 • 517 citations

Transferrin-polycation-DNA complexes: the effect of polycations on the structure of the complex and DNA delivery to cells.

1991 • 485 citations

Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes.

1992 • 483 citations

Adenovirus enhancement of transferrin-polylysine-mediated gene delivery.

1991 • 431 citations

Membrane Traffic in Endocytosis: Insights from Cell-Free Assays

1989 • 369 citations

Brominating Oxidants Generated by Human Eosinophils

1986 • 364 citations

Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats

1991 • 349 citations

Colorimetric determination of neutral sugars by a resorcinol sulfuric acid micromethod

1988 • 343 citations

Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels.

1990 • 340 citations

Carbohydrate ligands of the LEC cell adhesion molecules

1990 • 338 citations

High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles.

1992 • 317 citations

Targeting Genes: Delivery and Persistent Expression of a Foreign Gene Driven by Mammalian Regulatory Elements in Vivo

1989 • 292 citations

Receptor-mediated endocytosis of transferrin-polycation conjugates: an efficient way to introduce DNA into hematopoietic cells.

1990 • 275 citations

Characterization of the asialoglycoprotein receptor in a continuous hepatoma line.

1981 • 273 citations

Membrane binding and conformational properties of peptides representing the NH2 terminus of influenza HA-2.

1987 • 252 citations

Hepatocyte-directed gene transfer in vivo leads to transient improvement of hypercholesterolemia in low density lipoprotein receptor-deficient rabbits.

1992 • 242 citations

High-Efficiency Gene Transfer Mediated by Adenovirus Coupled to DNA–Polylysine Complexes

1992 • 234 citations

Uptake of neoglycoproteins via membrane lectin(s) of L1210 cells evidenced by quantitative flow cytofluorometry and drug targeting

1984 • 222 citations

Evidence for targeted gene delivery to Hep G2 hepatoma cells in vitro

1988 • 221 citations

The mechanism of receptor‐mediated endocytosis

1991 • 164 citations

DNA-binding transferrin conjugates as functional gene-delivery agents: synthesis by linkage of polylysine or ethidium homodimer to the transferrin carbohydrate moiety

1991 • 142 citations

pH-Dependent Membrane Fusion Activity of a Synthetic Twenty Amino Acid Peptide with the Same Sequence as That of the Hydrophobic Segment of Influenza Virus Hemagglutinin1

1987 • 119 citations

Sugar‐specific endocytosis of glycoproteins by Lewis lung carcinoma cells

1983 • 118 citations

Mechanisms of enveloped virus entry into cells.

1990 • 104 citations

Receptor-mediated endocytosis and nuclear transport of a transfecting DNA construct

1992 • 102 citations

Conformation of membrane fusion-active 20-residue peptides with or without lipid bilayers. Implication of .alpha.-helix formation for membrane fusion

1990 • 94 citations

Characterization and biological implications of membrane lectins in tumor, lymphoid and myeloid cells

1988 • 92 citations

pH-Dependent membrane fusion and vesiculation of phospholipid large unilamellar vesicles induced by amphiphilic anionic and cationic peptides

1992 • 91 citations

Drug targeting: synthesis and endocytosis of oligonucleotide-neoglycoprotein conjugates

1992 • 90 citations

Quantitation of the binding, uptake, and degradation of fluoresceinylated neoglycoproteins by flow cytometry

1987 • 78 citations

Muramyl dipeptide bound to poly-l-lysine substituted with mannose and gluconoyl residues as macrophage activators

1989 • 72 citations

Uptake by macrophages of a biotinylated oligo-.alpha.-deoxythymidylate by using mannosylated streptavidin

1992 • 34 citations

Membrane fusion induced by mutual interaction of the two charge-reversed amphiphilic peptides at neutral pH

1991 • 33 citations

Endocytosis mediated by monocyte and macrophage membrane lectins — application to antiviral drug targeting

1990 • 31 citations

Modification of the N-terminus of membrane fusion-active peptides blocks the fusion activity

1991 • 16 citations