Mechanism of gene regulation by steroid hormones

Genomic sequencing.

1984 • 8,343 citations

Efficient isolation of genes by using antibody probes.

1983 • 2,065 citations

Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene

1984 • 955 citations

Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region

1983 • 700 citations

DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo

1983 • 692 citations

The glucocorticoid receptor binds to defined nucleotide sequences near the promoter of mouse mammary tumour virus

1983 • 619 citations

The hormone regulatory element of mouse mammary tumour virus mediates progesterone induction.

1986 • 406 citations

Glucocorticoid and progesterone receptors bind to the same sites in two hormonally regulated promoters

1985 • 366 citations

Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment whose transcription is regulated by glucocorticoids in vivo.

1981 • 341 citations

Sequences in the promoter region of the chicken lysozyme gene required for steroid regulation and receptor binding

1984 • 281 citations

Characterization of a steroid hormone receptor gene and mRNA in wild-type and mutant cells

1984 • 278 citations

Contacts between hormone receptor and DNA double helix within a glucocorticoid regulatory element of mouse mammary tumor virus.

1984 • 247 citations

Glucocorticoid receptor binding and activation of a heterologous promoter by dexamethasone by the first intron of the human growth hormone gene.

1985 • 235 citations

Hormonal response region in the mouse mammary tumor virus long terminal repeat can be dissociated from the proviral promoter and has enhancer properties.

1985 • 164 citations

Specific transcription of mouse ribosomal DNA in a cell-free system that mimics control in vivo.

1981 • 159 citations

Glucocorticoid receptors recognize DNA sequences in and around murine mammary tumour virus DNA.

1982 • 153 citations

Induction of ovalbumin mRNA sequences by estrogen and progesterone in chick oviduct as measured by hybridization to complementary DNA.

1975 • 150 citations

The nucleotide sequences recognized by the glucocorticoid receptor in the rabbit uteroglobin gene region are located far upstream from the initiation of transcription.

1984 • 125 citations

Molecular Model of the Interaction Between the Glucocorticoid Receptor and the Regulatory Elements of Inducible Genes

1986 • 117 citations

Monoclonal antibodies to the rat liver glucocorticoid receptor.

1982 • 113 citations

Determination of the promoter region of mouse ribosomal RNA gene by an in vitro transcription system.

1984 • 94 citations

Mechanisms of glucocorticoid hormone action

1984 • 77 citations

The uteroglobin gene region: hormonal regulation, repetitive elements and complete nucleotide sequence of the gene

1983 • 69 citations

Glucocorticoids directly affect the synthesis of ribosomal RNA in rat-liver cells

1982 • 17 citations

The hormonal regulation of uteroglobin gene expression.

1985 • 14 citations